Sequential activation of heterogeneous macrophage phenotypes is essential for biomaterials-induced bone regeneration
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Sequential activation of heterogeneous macrophage phenotypes is essential for biomaterials-induced bone regeneration
Authors
Keywords
Macrophage, Bone regeneration, Osteogenesis, Angiogenesis, Immunomodulation
Journal
BIOMATERIALS
Volume 276, Issue -, Pages 121038
Publisher
Elsevier BV
Online
2021-07-28
DOI
10.1016/j.biomaterials.2021.121038
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Macrophages of diverse phenotypes drive vascularization of engineered tissues
- (2020) P. L. Graney et al. Science Advances
- Engineered biomaterials for in situ tissue regeneration
- (2020) Akhilesh K. Gaharwar et al. Nature Reviews Materials
- Multinucleated Giant Cell Formation as a Portal to Chronic Bacterial Infections
- (2020) Jacob L. Stockton et al. Microorganisms
- Interaction between the integrin Mac-1 and signal regulatory protein α (SIRPα) mediates fusion in heterologous cells
- (2019) Nataly P. Podolnikova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration
- (2019) Bo Gao et al. JOURNAL OF CLINICAL INVESTIGATION
- The macrophage checkpoint CD47 : SIRPα for recognition of ‘self’ cells: from clinical trials of blocking antibodies to mechanobiological fundamentals
- (2019) Jason C. Andrechak et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Molecular determinants for the polarization of macrophage and osteoclast
- (2019) Dengbao Yang et al. Seminars in Immunopathology
- 3D-printed nanocomposite scaffolds with tunable magnesium ionic microenvironment induce in situ bone tissue regeneration
- (2019) Jie Shen et al. Applied Materials Today
- Identification of Functionally Distinct Mx1+αSMA+ Periosteal Skeletal Stem Cells
- (2019) Laura C. Ortinau et al. Cell Stem Cell
- Design of biodegradable, implantable devices towards clinical translation
- (2019) Chunmei Li et al. Nature Reviews Materials
- Macrophages in bone fracture healing: Their essential role in endochondral ossification
- (2018) Claudia Schlundt et al. BONE
- Common signalling pathways in macrophage and osteoclast multinucleation
- (2018) Marie Pereira et al. JOURNAL OF CELL SCIENCE
- IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis
- (2018) Charlie Bridgewood et al. Frontiers in Immunology
- Contribution of the in situ release of endogenous cations from xenograft bone driven by fluoride incorporation toward enhanced bone regeneration
- (2018) Wei Qiao et al. Biomaterials Science
- Interleukin-22 promotes tumor angiogenesis
- (2018) Nicholas J. Protopsaltis et al. ANGIOGENESIS
- IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge
- (2017) Olga Spadaro et al. Cell Reports
- RANKL-induced M1 macrophages are involved in bone formation
- (2017) Rong Huang et al. Bone Research
- Giant cells around bone biomaterials: Osteoclasts or multi-nucleated giant cells?
- (2016) Richard J. Miron et al. Acta Biomaterialia
- OsteoMacs: Key players around bone biomaterials
- (2016) Richard J. Miron et al. BIOMATERIALS
- Osteoimmunomodulation for the development of advanced bone biomaterials
- (2016) Zetao Chen et al. Materials Today
- Oncostatin M, an Inflammatory Cytokine Produced by Macrophages, Supports Intramembranous Bone Healing in a Mouse Model of Tibia Injury
- (2015) Pierre Guihard et al. AMERICAN JOURNAL OF PATHOLOGY
- Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds
- (2015) Kara L. Spiller et al. BIOMATERIALS
- Macrophages Promote Osteoblastic Differentiation In Vivo: Implications in Fracture Repair and Bone Homeostasis
- (2015) Linda Vi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- High-Temperature Sintering of Xenogeneic Bone Substitutes Leads to Increased Multinucleated Giant Cell Formation: In Vivo and Preliminary Clinical Results
- (2015) Mike Barbeck et al. Journal of Oral Implantology
- TRAP-Positive Multinucleated Giant Cells Are Foreign Body Giant Cells Rather Than Osteoclasts: Results From a Split-Mouth Study in Humans
- (2015) Jonas Lorenz et al. Journal of Oral Implantology
- Multinucleated Giant Cells Are Specialized for Complement-Mediated Phagocytosis and Large Target Destruction
- (2015) Ronny Milde et al. Cell Reports
- The Foreign Body Giant Cell Cannot Resorb Bone, But Dissolves Hydroxyapatite Like Osteoclasts
- (2015) Bas ten Harkel et al. PLoS One
- Mesenchymal stroma cells trigger early attraction of M1 macrophages and endothelial cells into fibrin hydrogels, stimulating long bone healing without long-term engraftment
- (2014) Elisabeth Seebach et al. Acta Biomaterialia
- Fracture Healing via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Early Endochondral Ossification
- (2014) Liza J. Raggatt et al. AMERICAN JOURNAL OF PATHOLOGY
- Bone tissue formation with human mesenchymal stem cells and biphasic calcium phosphate ceramics: The local implication of osteoclasts and macrophages
- (2014) Anne-Laure Gamblin et al. BIOMATERIALS
- The role of macrophage phenotype in vascularization of tissue engineering scaffolds
- (2014) Kara L. Spiller et al. BIOMATERIALS
- Identification of differentiation-stage specific markers that define the ex vivo osteoblastic phenotype
- (2014) Natalie A. Twine et al. BONE
- Interleukin-1 Receptor-associated Kinase-4 (IRAK4) Promotes Inflammatory Osteolysis by Activating Osteoclasts and Inhibiting Formation of Foreign Body Giant Cells
- (2014) Eri Katsuyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential Expression of Chemokines, Chemokine Receptors and Proteinases by Foreign Body Giant Cells (FBGCs) and Osteoclasts
- (2014) Usman A. Khan et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo
- (2014) M. K. Chang et al. JOURNAL OF IMMUNOLOGY
- Long-Term Stability of Contour Augmentation in the Esthetic Zone: Histologic and Histomorphometric Evaluation of 12 Human Biopsies 14 to 80 Months After Augmentation
- (2014) Simon S. Jensen et al. JOURNAL OF PERIODONTOLOGY
- PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis
- (2014) Hui Xie et al. NATURE MEDICINE
- Fracture healing: mechanisms and interventions
- (2014) Thomas A. Einhorn et al. Nature Reviews Rheumatology
- MCP/CCR2 Signaling Is Essential for Recruitment of Mesenchymal Progenitor Cells during the Early Phase of Fracture Healing
- (2014) Masahiro Ishikawa et al. PLoS One
- Kcnn4 Is a Regulator of Macrophage Multinucleation in Bone Homeostasis and Inflammatory Disease
- (2014) Heeseog Kang et al. Cell Reports
- From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation
- (2014) Paola Italiani et al. Frontiers in Immunology
- Low-modulus Mg/PCL hybrid bone substitute for osteoporotic fracture fixation
- (2013) Hoi Man Wong et al. BIOMATERIALS
- An Essential Role for STAT6-STAT1 Protein Signaling in Promoting Macrophage Cell-Cell Fusion
- (2012) Hiroya Miyamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endoplasmic Reticulum Stress Controls M2 Macrophage Differentiation and Foam Cell Formation
- (2012) Jisu Oh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fracture healing under healthy and inflammatory conditions
- (2012) Lutz Claes et al. Nature Reviews Rheumatology
- Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling
- (2012) Pierre Guihard et al. STEM CELLS
- Scaffold vascularization in vivo driven by primary human osteoblasts in concert with host inflammatory cells
- (2011) Shahram Ghanaati et al. BIOMATERIALS
- The stimulation of an osteogenic response by classical monocyte activation
- (2011) Omar M. Omar et al. BIOMATERIALS
- Foreign body-type multinucleated giant cells induced by interleukin-4 express select lymphocyte co-stimulatory molecules and are phenotypically distinct from osteoclasts and dendritic cells
- (2011) Amy K. McNally et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model
- (2011) Kylie A Alexander et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Targeting osteoclast-osteoblast communication
- (2011) Xu Cao NATURE MEDICINE
- Genetic Ablation of CD68 Results in Mice with Increased Bone and Dysfunctional Osteoclasts
- (2011) Jason W. Ashley et al. PLoS One
- Signaling networks in RUNX2-dependent bone development
- (2010) Toshihisa Komori JOURNAL OF CELLULAR BIOCHEMISTRY
- A biodegradable polymer-based coating to control the performance of magnesium alloy orthopaedic implants
- (2009) Hoi Man Wong et al. BIOMATERIALS
- Osteoclasts are important for bone angiogenesis
- (2009) F. C. Cackowski et al. BLOOD
- Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation
- (2009) Takako Negishi-Koga et al. IMMUNOLOGICAL REVIEWS
- Tartrate-resistant acid phosphatase (TRAP) and the osteoclast/immune cell dichotomy
- (2008) Alison R. Hayman AUTOIMMUNITY
- Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling
- (2008) Michelle M. McDonald et al. BONE
- Osteoimmunology: Interactions of the Bone and Immune System
- (2008) Joseph Lorenzo et al. ENDOCRINE REVIEWS
- Comparison of Effects of the Bisphosphonate Alendronate Versus the RANKL Inhibitor Denosumab on Murine Fracture Healing
- (2008) Louis C Gerstenfeld et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The impact of colony-stimulating factor-1 on fracture healing: An experimental study
- (2008) Kambiz Sarahrudi et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Foreign body reaction to biomaterials
- (2008) James M. Anderson et al. SEMINARS IN IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started