Molecular determinants for the polarization of macrophage and osteoclast

Peroxisome Proliferator-Activated Receptor-γ Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids

(2018) Michael Heming et al.   Frontiers in Immunology

MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα

(2017) Seyeon Bae et al.   JOURNAL OF CLINICAL INVESTIGATION

Milk lipid regulation at the maternal-offspring interface

(2017) Dengbao Yang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

(2017) Kyung Cheul Shin et al.   Nature Communications

mTOR Inhibition Subdues Milk Disorder Caused by Maternal VLDLR Loss

(2017) HoangDinh Huynh et al.   Cell Reports

ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction

(2017) Xiang He et al.   PLoS Pathogens

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

Ligand Activation of ERRα by Cholesterol Mediates Statin and Bisphosphonate Effects

(2016) Wei Wei et al.   Cell Metabolism

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

(2016) Stanley Ching-Cheng Huang et al.   IMMUNITY

PGC-1β suppresses saturated fatty acid-induced macrophage inflammation by inhibiting TAK1 activation

(2016) Hongen Chen et al.   IUBMB LIFE

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

(2016) Jan Van den Bossche et al.   Cell Reports

PPARG Post-translational Modifications Regulate Bone Formation and Bone Resorption

(2016) L.A. Stechschulte et al.   EBioMedicine

Macrophages: Development and Tissue Specialization

(2015) Chen Varol et al.   Annual Review of Immunology

The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo

(2015) Petra Sabine Eisele et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation

(2015) Jae-Min Yuk et al.   IMMUNITY

Macrophages: Their Emerging Roles in Bone

(2015) Benjamin P Sinder et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles

(2015) Thanuja Gali Ramamoorthy et al.   Nature Communications

The multiple universes of estrogen-related receptor α and γ in metabolic control and related diseases

(2014) Étienne Audet-walsh et al.   ACTA PHARMACOLOGICA SINICA

Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency

(2014) Jinhu Xiong et al.   BONE

Thiazolidinediones and the Promise of Insulin Sensitization in Type 2 Diabetes

(2014) Raymond E. Soccio et al.   Cell Metabolism

Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization

(2014) Zixue Jin et al.   Cell Metabolism

Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo

(2014) M. K. Chang et al.   JOURNAL OF IMMUNOLOGY

Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages

(2014) Christoph Schneider et al.   NATURE IMMUNOLOGY

Hepatic-specific activation of peroxisome proliferator-activated receptor γ coactivator-1β protects against steatohepatitis

(2013) Elena Bellafante et al.   HEPATOLOGY

Very Low Density Lipoprotein Receptor (VLDLR) Expression Is a Determinant Factor in Adipose Tissue Inflammation and Adipocyte-Macrophage Interaction

(2013) Andrew Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The TSC-mTOR pathway regulates macrophage polarization

(2013) Vanessa Byles et al.   Nature Communications

Mice lacking PGC-1β in adipose tissues reveal a dissociation between mitochondrial dysfunction and insulin resistance

(2013) Natàlia Enguix et al.   Molecular Metabolism

Monocytes Induce STAT3 Activation in Human Mesenchymal Stem Cells to Promote Osteoblast Formation

(2012) Vicky Nicolaidou et al.   PLoS One

Liver-Specific PGC-1beta Deficiency Leads to Impaired Mitochondrial Function and Lipogenic Response to Fasting-Refeeding

(2012) Kari T. Chambers et al.   PLoS One

New insights into osteoclastogenic signaling mechanisms

(2012) Tomoki Nakashima et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates

(2012) Yang Du et al.   Nature Communications

Understanding mitochondrial complex I assembly in health and disease

(2011) Masakazu Mimaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A mitochondrial etiology of Alzheimer and Parkinson disease

(2011) Pinar Coskun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibition of PPAR  in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis

(2011) L. Wu et al.   BLOOD

Osteoclast Progenitors Reside in the Peroxisome Proliferator-Activated Receptor  -Expressing Bone Marrow Cell Population

(2011) W. Wei et al.   MOLECULAR AND CELLULAR BIOLOGY

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss

(2010) Wei Wei et al.   Cell Metabolism

Involvement of the orphan nuclear estrogen receptor-related receptor α in osteoclast adhesion and transmigration

(2010) Edith Bonnelye et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Breast Milk as the Gold Standard for Protective Nutrients

(2010) Allan Walker   JOURNAL OF PEDIATRICS

Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome

(2010) A. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARγ in bone homeostasis

(2010) Yihong Wan   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Absence of Estrogen Receptor-Related-α Increases Osteoblastic Differentiation and Cancellous Bone Mineral Density

(2009) I. Delhon et al.   ENDOCRINOLOGY

Rosiglitazone activation of PPARγ suppresses fractalkine signaling

(2009) Yihong Wan et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

(2009) Kiyo-aki Ishii et al.   NATURE MEDICINE

Absence of ERRα in Female Mice Confers Resistance to Bone Loss Induced by Age or Estrogen-Deficiency

(2009) Catherine Teyssier et al.   PLoS One

Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy

(2008) Shane E. Kruse et al.   Cell Metabolism

Normal Bone Anatomy and Physiology

(2008) B. Clarke   Clinical Journal of the American Society of Nephrology

Rosiglitazone-Associated Fractures in Type 2 Diabetes: An analysis from A Diabetes Outcome Progression Trial (ADOPT)

(2008) S. E. Kahn et al.   DIABETES CARE

Osteoimmunology: Interactions of the Bone and Immune System

(2008) Joseph Lorenzo et al.   ENDOCRINE REVIEWS

Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors

(2008) Vincent Giguère   ENDOCRINE REVIEWS

Transcriptional coactivators PGC-1  and PGC-l  control overlapping programs required for perinatal maturation of the heart

(2008) L. Lai et al.   GENES & DEVELOPMENT