Current State of Targeted Radiometal-Based Constructs for the Detection and Treatment of Disease in the Brain

Synthesis and preclinical evaluation of the 99mTc-/177Lu-CXCR4-L theranostic pair for in vivo chemokine-4 receptor-specific targeting

(2020) Marcela Ávila-Sánchez et al.   JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY

A Proof-of-Concept Study on the Therapeutic Potential of Au Nanoparticles Radiolabeled with the Alpha-Emitter Actinium-225

(2020) Evangelia-Alexandra Salvanou et al.   Pharmaceutics

99mTc-CXCR4-L for Imaging of the Chemokine-4 Receptor Associated with Brain Tumor Invasiveness: Biokinetics, Radiation Dosimetry, and Proof of Concept in Humans

(2020) Paola Vallejo-Armenta et al.   Contrast Media & Molecular Imaging

225Ac- and 213Bi-Substance P Analogues for Glioma Therapy

(2020) Leszek Królicki et al.   SEMINARS IN NUCLEAR MEDICINE

Advancements in PARP1 Targeted Nuclear Imaging and Theranostic Probes

(2020) Ramya Ambur Sankaranarayanan et al.   Journal of Clinical Medicine

Development of a CD19 PET tracer for detecting B cells in a mouse model of multiple sclerosis

(2020) Marc Y. Stevens et al.   Journal of Neuroinflammation

Chlorotoxin peptide-functionalized polyethylenimine-entrapped gold nanoparticles for glioma SPECT/CT imaging and radionuclide therapy

(2019) Lingzhou Zhao et al.   JOURNAL OF NANOBIOTECHNOLOGY

Human Brain Endothelial CXCR2 is Inflammation-Inducible and Mediates CXCL5- and CXCL8-Triggered Paraendothelial Barrier Breakdown

(2019) Axel Haarmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Differential Uptake of 68Ga-PSMA-HBED-CC (PSMA-11) in Low-Grade Versus High-Grade Gliomas in Treatment-Naive Patients

(2019) Priyanka Verma et al.   CLINICAL NUCLEAR MEDICINE

68Ga-labeled dimeric and trimeric cyclic RGD peptides as potential PET radiotracers for imaging gliomas

(2019) Zuo-Quan Zhao et al.   APPLIED RADIATION AND ISOTOPES

Impaired brain dopamine transporter in chemobrain patients submitted to brain SPECT imaging using the technetium-99m labeled tracer TRODAT-1

(2019) Taise Vitor et al.   ANNALS OF NUCLEAR MEDICINE

Targeting PARP-1 with alpha-particles is potently cytotoxic to human neuroblastoma in pre-clinical models

(2019) Mehran Makvandi et al.   MOLECULAR CANCER THERAPEUTICS

Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival

(2019) Sandrine Dufort et al.   JOURNAL OF CLINICAL NEUROSCIENCE

A Picture of Modern Tc-99m Radiopharmaceuticals: Production, Chemistry, and Applications in Molecular Imaging

(2019) Alessandra Boschi et al.   Applied Sciences-Basel

Current and Future Trends on Diagnosis and Prognosis of Glioblastoma: From Molecular Biology to Proteomics

(2019) Silantyev et al.   Cells

The Significance of NK1 Receptor Ligands and Their Application in Targeted Radionuclide Tumour Therapy

(2019) Agnieszka Majkowska-Pilip et al.   Pharmaceutics

First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound

(2019) Agessandro Abrahao et al.   Nature Communications

68Ga–Prostate-Specific Membrane Antigen-11 PET/CT

(2019) Jolanta Kunikowska et al.   CLINICAL NUCLEAR MEDICINE

Prolonged survival in secondary glioblastoma following local injection of targeted alpha therapy with 213Bi-substance P analogue

(2018) Leszek Krolicki et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Evaluation of 177 Lu[Lu]-CHX-A″-DTPA-6A10 Fab as a radioimmunotherapy agent targeting carbonic anhydrase XII

(2018) L. Fiedler et al.   NUCLEAR MEDICINE AND BIOLOGY

Current Strategies for Brain Drug Delivery

(2018) Xiaowei Dong   Theranostics

Biodistribution and Internal Radiation Dosimetry of 99mTc-IDA-D-[c(RGDfK)]2 (BIK-505), a Novel SPECT Radiotracer for the Imaging of Integrin αvβ3 Expression

(2018) Yoo Sung Song et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Efficacy and Safety of High-Specific-Activity I-131 MIBG Therapy in Patients with Advanced Pheochromocytoma or Paraganglioma

(2018) Daniel A. Pryma et al.   JOURNAL OF NUCLEAR MEDICINE

PET imaging of intra-arterial 89Zr bevacizumab in mice with and without osmotic opening of the blood-brain barrier: distinct advantage of intra-arterial delivery

(2018) Wojciech G. Lesniak et al.   JOURNAL OF NUCLEAR MEDICINE

68Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy

(2017) Penelope Bouziotis et al.   Nanomedicine

Rationally Designed Peptides and Peptidomimetics as Inhibitors of Amyloid-β (Aβ) Aggregation: Potential Therapeutics of Alzheimer’s Disease

(2017) Deepti Goyal et al.   ACS Combinatorial Science

Peptide-based PET imaging of the tumor restricted IL13RA2 biomarker

(2017) Kiran Kumar Solingapuram Sai et al.   Oncotarget

IL13RA2 targeted alpha particle therapy against glioblastomas

(2017) Anirudh Sattiraju et al.   Oncotarget

Extracellular Vesicles As Modulators of Tumor Microenvironment and Disease Progression in Glioma

(2017) Abir Mondal et al.   Frontiers in Oncology

Gallium and its competing roles with iron in biological systems

(2016) Christopher R. Chitambar   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Noninvasive Measurement of mTORC1 Signaling with 89 Zr-Transferrin

(2016) Charles Truillet et al.   CLINICAL CANCER RESEARCH

Vascular Targeted Radioimmunotherapy for the Treatment of Glioblastoma

(2016) K. Behling et al.   JOURNAL OF NUCLEAR MEDICINE

Molecular Drug Imaging:89Zr-Bevacizumab PET in Children with Diffuse Intrinsic Pontine Glioma

(2016) Marc H. Jansen et al.   JOURNAL OF NUCLEAR MEDICINE

Synthesis and Characterization of 89Zr-Labeled Ultrasmall Nanoparticles

(2016) Charles Truillet et al.   MOLECULAR PHARMACEUTICS

Gadolinium-Based Nanoparticles and Radiation Therapy for Multiple Brain Melanoma Metastases: Proof of Concept before Phase I Trial

(2016) Shady Kotb et al.   Theranostics

68Ga-Labeled 3PRGD2 for Dual PET and Cerenkov Luminescence Imaging of Orthotopic Human Glioblastoma

(2015) Di Fan et al.   BIOCONJUGATE CHEMISTRY

TGF-  Antibody Uptake in Recurrent High-Grade Glioma Imaged with 89Zr-Fresolimumab PET

(2015) M. W. den Hollander et al.   JOURNAL OF NUCLEAR MEDICINE

Peptides and the blood–brain barrier

(2015) William A. Banks   PEPTIDES

Noninvasive brain cancer imaging with a bispecific antibody fragment, generated via click chemistry

(2015) Haiming Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted delivery of protein and gene medicines through the blood-brain barrier

(2015) WM Pardridge   CLINICAL PHARMACOLOGY & THERAPEUTICS

Presenting symptoms of glioma in adults

(2014) J. P. Posti et al.   ACTA NEUROLOGICA SCANDINAVICA

Matching the Decay Half-Life with the Biological Half-Life: ImmunoPET Imaging with 44Sc-Labeled Cetuximab Fab Fragment

(2014) Rubel Chakravarty et al.   BIOCONJUGATE CHEMISTRY

Targeted delivery of silver nanoparticles and alisertib: in vitro and in vivo synergistic effect against glioblastoma

(2014) Erica Locatelli et al.   Nanomedicine

Intrathecal delivery of protein therapeutics to the brain: A critical reassessment

(2014) Pericles Calias et al.   PHARMACOLOGY & THERAPEUTICS

Review Glioblastoma multiforme – an overview

(2014) Kaja Urbańska et al.   Wspolczesna Onkologia-Contemporary Oncology

Choline-containing phospholipids: relevance to brain functional pathways

(2013) Seyed Khosrow Tayebati et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Ultrasound-mediated strategies in opening brain barriers for drug brain delivery

(2013) Ying-Zheng Zhao et al.   Expert Opinion on Drug Delivery

CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma

(2012) Stuart J. Smith et al.   ACTA NEUROPATHOLOGICA

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Imaging Tumor Burden in the Brain with 89Zr-Transferrin

(2012) M. J. Evans et al.   JOURNAL OF NUCLEAR MEDICINE

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2005-2009

(2012) T. A. Dolecek et al.   NEURO-ONCOLOGY

Synthesis and biological evaluation of RGD peptides with the99mTc/188Re chelated iminodiacetate core: highly enhanced uptake and excretion kinetics of theranostics against tumor angiogenesis

(2012) Byung Chul Lee et al.   RSC Advances

Current concepts and management of glioblastoma

(2011) Matthias Preusser et al.   ANNALS OF NEUROLOGY

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

(2011) Cris S Constantinescu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Phase I single-dose study of intracavitary-administered Nimotuzumab labeled with 188-Re in adult recurrent high-grade glioma

(2010) Angel Casaco et al.   CANCER BIOLOGY & THERAPY

Targeted alpha-radionuclide therapy of functionally critically located gliomas with 213Bi-DOTA-[Thi8,Met(O2)11]-substance P: a pilot trial

(2010) D. Cordier et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Strategy for effective brain drug delivery

(2010) M. Intakhab Alam et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Characteristics of compounds that cross the blood-brain barrier

(2009) William A Banks   BMC Neurology

The Austrian Brain Tumour Registry: a cooperative way to establish a population-based brain tumour registry

(2009) Adelheid Wöhrer et al.   JOURNAL OF NEURO-ONCOLOGY

Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS

(2008) Gabriel A Silva   BMC NEUROSCIENCE