Engineering potassium activation into biosynthetic thiolase

Mutation update on ACAT1 variants associated with mitochondrial acetoacetyl‐CoA thiolase (T2) deficiency

(2019) Elsayed Abdelkreem et al.   HUMAN MUTATION

Why Nature Chose Potassium

(2019) Antoine Danchin et al.   JOURNAL OF MOLECULAR EVOLUTION

Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action

(2019) Matthew E. Bergman et al.   MOLECULES

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations

(2018) Andrew C. Marshall et al.   ACS Catalysis

MX2: a high-flux undulator microfocus beamline serving both the chemical and macromolecular crystallography communities at the Australian Synchrotron

(2018) David Aragão et al.   JOURNAL OF SYNCHROTRON RADIATION

Structural Insights into Polyhydroxyalkanoates Biosynthesis

(2018) Hye-Young Sagong et al.   TRENDS IN BIOCHEMICAL SCIENCES

Recent advances in understanding beta-ketothiolase (mitochondrial acetoacetyl-CoA thiolase, T2) deficiency

(2018) Toshiyuki Fukao et al.   JOURNAL OF HUMAN GENETICS

Evolution of cation binding in the active sites of P-loop nucleoside triphosphatases in relation to the basic catalytic mechanism

(2018) Daria N Shalaeva et al.   eLife

Mitochondrial acetoacetyl-CoA thiolase deficiency: basal ganglia impairment may occur independently of ketoacidosis

(2017) Stéphanie Paquay et al.   JOURNAL OF INHERITED METABOLIC DISEASE

CheckMyMetal: a macromolecular metal-binding validation tool

(2017) Heping Zheng et al.   Acta Crystallographica Section D-Structural Biology

Molecular Mechanisms of Enzyme Activation by Monovalent Cations

(2016) David W. Gohara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Why Ser and Not Thr Brokers Catalysis in the Trypsin Fold

(2015) Leslie A. Pelc et al.   BIOCHEMISTRY

Assessing and maximizing data quality in macromolecular crystallography

(2015) P Andrew Karplus et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

MX1: a bending-magnet crystallography beamline serving both chemical and macromolecular crystallography communities at the Australian Synchrotron

(2015) Nathan Philip Cowieson et al.   JOURNAL OF SYNCHROTRON RADIATION

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cation−π Interaction: Its Role and Relevance in Chemistry, Biology, and Material Science

(2012) A. Subha Mahadevi et al.   CHEMICAL REVIEWS

Expression, Identification and Purification of Dictyostelium Acetoacetyl-CoA Thiolase Expressed in Escherichia coli

(2012) Takeshi Tanaka et al.   International Journal of Biological Sciences

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

CD-HIT Suite: a web server for clustering and comparing biological sequences

(2010) Ying Huang et al.   BIOINFORMATICS

Metals in protein structures: a review of their principal features

(2010) Marjorie M. Harding et al.   Crystallography Reviews

The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation

(2009) Gitte Meriläinen et al.   BIOCHEMISTRY

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

Mutant N143P Reveals How Na+Activates Thrombin

(2009) Weiling Niu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering Protein Allostery: 1.05 Å Resolution Structure and Enzymatic Properties of a Na+-activated Trypsin

(2008) Michael J. Page et al.   JOURNAL OF MOLECULAR BIOLOGY