Molecular aspects of β, β-carotene-9′, 10′-oxygenase 2 in carotenoid metabolism and diseases

Lycopene Attenuated Hepatic Tumorigenesis via Differential Mechanisms Depending on Carotenoid Cleavage Enzyme in Mice

(2014) B. C. Ip et al.   Cancer Prevention Research

Evidence for compartmentalization of mammalian carotenoid metabolism

(2014) Grzegorz Palczewski et al.   FASEB JOURNAL

β-Carotene-9′,10′-Oxygenase Status Modulates the Impact of Dietary Tomato and Lycopene on Hepatic Nuclear Receptor–, Stress-, and Metabolism-Related Gene Expression in Mice

(2014) Hsueh-Li Tan et al.   JOURNAL OF NUTRITION

Lycopene and Apo-10′-lycopenoic Acid Have Differential Mechanisms of Protection against Hepatic Steatosis in β-Carotene-9′,10′-oxygenase Knockout Male Mice

(2014) Blanche C Ip et al.   JOURNAL OF NUTRITION

Wolfberries potentiate mitophagy and enhance mitochondrial biogenesis leading to prevention of hepatic steatosis in obese mice: The role of AMP-activated protein kinase α2 subunit

(2014) Dingbo Lin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mitochondrial Respiratory Supercomplex Association Limits Production of Reactive Oxygen Species from Complex I

(2013) Evelina Maranzana et al.   ANTIOXIDANTS & REDOX SIGNALING

Functional role of mitochondrial respiratory supercomplexes

(2013) Maria Luisa Genova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A critical appraisal of the role of respiratory supercomplexes in mitochondria

(2013) Maria Luisa Genova et al.   BIOLOGICAL CHEMISTRY

Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism

(2013) Jaume Amengual et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carotenoid metabolism in mammals, including man: formation, occurrence, and function of apocarotenoids

(2013) Abdulkerim Eroglu et al.   JOURNAL OF LIPID RESEARCH

Genetic ablation of carotene oxygenases and consumption of lycopene or tomato powder diets modulate carotenoid and lipid metabolism in mice

(2013) Nikki A. Ford et al.   NUTRITION RESEARCH

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver

(2013) C Chang et al.   ONCOGENE

A global clinical view on vitamin A and carotenoids

(2012) Alfred Sommer et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Lycopene metabolism and its biological significance

(2012) Xiang-Dong Wang   AMERICAN JOURNAL OF CLINICAL NUTRITION

Provitamin A metabolism and functions in mammalian biology

(2012) Johannes von Lintig   AMERICAN JOURNAL OF CLINICAL NUTRITION

Mitochondrial Complex I Plays an Essential Role in Human Respirasome Assembly

(2012) David Moreno-Lastres et al.   Cell Metabolism

BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway

(2012) G. P. Lobo et al.   DEVELOPMENT

In vivoandin vitrostudies on the carotenoid cleavage oxygenases fromSphingopyxis alaskensis  RB2256 andPlesiocystis pacifica SIR-1 revealed their substrate specificities and non-retinal-forming cleavage activities

(2012) Jana Hoffmann et al.   FEBS Journal

The inflammation highway: metabolism accelerates inflammatory traffic in obesity

(2012) Amy R. Johnson et al.   IMMUNOLOGICAL REVIEWS

Naturally Occurring Eccentric Cleavage Products of Provitamin A β-Carotene Function as Antagonists of Retinoic Acid Receptors

(2012) Abdulkerim Eroglu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Editorial: Effect of Atorvastatin, Vitamin E and C on Nonalcoholic Fatty Liver Disease: Is the Combination Required?

(2011) Bianca M Arendt et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Absorption and metabolism of dietary carotenoids

(2011) Akihiko Nagao   BIOFACTORS

The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer

(2011) Ching-yi Chang et al.   CANCER CELL

Metabolism of Carotenoids and Retinoids Related to Vision

(2011) Johannes von Lintig   JOURNAL OF BIOLOGICAL CHEMISTRY

Importance of β,β-carotene 15,15′-monooxygenase 1 (BCMO1) and β,β-carotene 9′,10′-dioxygenase 2 (BCDO2) in nutrition and health

(2011) Georg Lietz et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Genomic Convergence among ERRα, PROX1, and BMAL1 in the Control of Metabolic Clock Outputs

(2011) Catherine R. Dufour et al.   PLoS Genetics

Colors with Functions: Elucidating the Biochemical and Molecular Basis of Carotenoid Metabolism

(2010) Johannes von Lintig   Annual Review of Nutrition

Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoid

(2010) Igor Shmarakov et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Molecular and dietary regulation of β,β-carotene 15,15′-monooxygenase 1 (BCMO1)

(2010) Georg Lietz et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Enzymatic formation of apo-carotenoids from the xanthophyll carotenoids lutein, zeaxanthin and β-cryptoxanthin by ferret carotene-9′,10′-monooxygenase

(2010) Jonathan R. Mein et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Genome-Wide Association Study Identifies Variants at the IL18 -BCO2 Locus Associated With Interleukin-18 Levels

(2010) Meian He et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumulation of carotenoids in adipose tissue in sheep (Ovis aries)

(2010) Dag I Våge et al.   BMC GENETICS

A mitochondrial enzyme degrades carotenoids and protects against oxidative stress

(2010) Jaume Amengual et al.   FASEB JOURNAL

β-Carotene Is an Important Vitamin A Source for Humans

(2010) Tilman Grune et al.   JOURNAL OF NUTRITION

An Update on the Health Effects of Tomato Lycopene

(2010) Erica N. Story et al.   Annual Review of Food Science and Technology

The conformation of end-groups is one determinant of carotenoid topology suitable for high fidelity molecular recognition: A study of β- and ε-end-groups

(2009) John T. Landrum et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse β-carotene 15, 15'-monooxygenase

(2009) Eugenia Poliakov et al.   BMC BIOCHEMISTRY

Mutation in Bovine  -Carotene Oxygenase 2 Affects Milk Color

(2009) S. D. Berry et al.   GENETICS

RPE65: Role in the Visual Cycle, Human Retinal Disease, and Gene Therapy

(2009) Xue Cai et al.   OPHTHALMIC GENETICS

Xanthophylls are preferentially taken up compared with β-carotene by retinal cells via a SRBI-dependent mechanism,

(2008) Alexandrine During et al.   JOURNAL OF LIPID RESEARCH

Nuclear Hormone Receptors for Heme: REV-ERBα and REV-ERBβ Are Ligand-Regulated Components of the Mammalian Clock

(2008) Thomas P. Burris   MOLECULAR ENDOCRINOLOGY

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)

(2008) David Melzer et al.   PLoS Genetics

Identification of the Yellow Skin Gene Reveals a Hybrid Origin of the Domestic Chicken

(2008) Jonas Eriksson et al.   PLoS Genetics