β-Carotene-9′,10′-Oxygenase Status Modulates the Impact of Dietary Tomato and Lycopene on Hepatic Nuclear Receptor–, Stress-, and Metabolism-Related Gene Expression in Mice

Complex interactions between dietary and genetic factors impact lycopene metabolism and distribution

(2013) Nancy E. Moran et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Evaluating the effect of lycopene from Lycopersicum esculentum on apoptosis during NDEA induced hepatocarcinogenesis

(2013) Prachi Gupta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lycopene Metabolite, Apo-10'-Lycopenoic Acid, Inhibits Diethylnitrosamine-Initiated, High Fat Diet-Promoted Hepatic Inflammation and Tumorigenesis in Mice

(2013) B. C. Ip et al.   Cancer Prevention Research

The Interactions of Dietary Tomato Powder and Soy Germ on Prostate Carcinogenesis in the TRAMP Model

(2013) K. E. Zuniga et al.   Cancer Prevention Research

Substrate Specificity of Purified Recombinant Human β-Carotene 15,15′-Oxygenase (BCO1)

(2013) Carlo dela Seña et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vitamin A and retinoid signaling: genomic and nongenomic effects

(2013) Ziad Al Tanoury et al.   JOURNAL OF LIPID RESEARCH

Differential Bioavailability, Clearance, and Tissue Distribution of the Acyclic Tomato Carotenoids Lycopene and Phytoene in Mongolian Gerbils

(2013) Nancy Engelmann Moran et al.   JOURNAL OF NUTRITION

Lycopene modulates growth and survival associated genes in prostate cancer

(2013) Mohamed M. Rafi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Strong and weak plasma response to dietary carotenoids identified by cluster analysis and linked to beta-carotene 15,15'-monooxygenase 1 single nucleotide polymorphisms

(2013) Thomas T.Y. Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Genetic ablation of carotene oxygenases and consumption of lycopene or tomato powder diets modulate carotenoid and lipid metabolism in mice

(2013) Nikki A. Ford et al.   NUTRITION RESEARCH

Lycopene supplementation suppresses oxidative stress induced by a high fat diet in gerbils

(2013) Soo-Kyong Choi et al.   Nutrition Research and Practice

Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma: Implications for Lycopene Intervention

(2013) Blanche Ip et al.   Nutrients

The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention

(2012) Yoav Sharoni et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Association between CSN3 and BCO2 gene polymorphisms and milk performance traits in the Czech Fleckvieh cattle breed

(2012) P. Bartonova et al.   GENETICS AND MOLECULAR RESEARCH

Naturally Occurring Eccentric Cleavage Products of Provitamin A β-Carotene Function as Antagonists of Retinoic Acid Receptors

(2012) Abdulkerim Eroglu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apo-10'-Lycopenoic Acid, a Lycopene Metabolite, Increases Sirtuin 1 mRNA and Protein Levels and Decreases Hepatic Fat Accumulation in ob/ob Mice

(2012) Jayong Chung et al.   JOURNAL OF NUTRITION

Nuclear receptors in regenerating liver and hepatocellular carcinoma

(2012) Michele Vacca et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet

(2012) Jiyun Ahn et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Lycopene counteracts the hepatic response to 7,12-dimethylbenz[a]anthracene by altering the expression of Bax, Bcl-2, caspases, and oxidative stress biomarkers

(2012) Can Ali Agca et al.   PHARMACEUTICAL BIOLOGY

The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer

(2011) Ching-yi Chang et al.   CANCER CELL

Lycopene inhibits the proliferation of androgen-dependent human prostate tumor cells through activation of PPARγ-LXRα-ABCA1 pathway

(2011) Chih-Min Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Lycopene and Apo-12'-Lycopenal Reduce Cell Proliferation and Alter Cell Cycle Progression in Human Prostate Cancer Cells

(2011) Nikki Ford et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Genomic Convergence among ERRα, PROX1, and BMAL1 in the Control of Metabolic Clock Outputs

(2011) Catherine R. Dufour et al.   PLoS Genetics

Genome-Wide Association Study Identifies Variants at the IL18 -BCO2 Locus Associated With Interleukin-18 Levels

(2010) Meian He et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A mitochondrial enzyme degrades carotenoids and protects against oxidative stress

(2010) Jaume Amengual et al.   FASEB JOURNAL

Nrf2/HO-1 signaling pathway may be the prime target for chemoprevention of cisplatin-induced nephrotoxicity by lycopene

(2010) Kazim Sahin et al.   FOOD AND CHEMICAL TOXICOLOGY

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

Identification and Quantification of Apo-lycopenals in Fruits, Vegetables, and Human Plasma

(2010) Rachel E. Kopec et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

β,β-Carotene Decreases Peroxisome Proliferator Receptor γ Activity and Reduces Lipid Storage Capacity of Adipocytes in a β,β-Carotene Oxygenase 1-dependent Manner

(2010) Glenn P. Lobo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Carotene-9′,10'-Monooxygenase Expression Increases Serum and Tissue Lycopene Concentrations in Lycopene-Fed Mice

(2010) Nikki A. Ford et al.   JOURNAL OF NUTRITION

Lycopene Epoxides and Apo-Lycopenals Formed by Chemical Reactions and Autoxidation in Model Systems and Processed Foods

(2009) Evelyn B. Rodriguez et al.   JOURNAL OF FOOD SCIENCE

Enzymatic metabolites of lycopene induce Nrf2‐mediated expression of phase II detoxifying/antioxidant enzymes in human bronchial epithelial cells

(2008) Fuzhi Lian et al.   INTERNATIONAL JOURNAL OF CANCER

Lycopene Biodistribution Is Altered in 15,15′-Carotenoid Monooxygenase Knockout Mice

(2008) Brian L. Lindshield et al.   JOURNAL OF NUTRITION

Nuclear Hormone Receptors for Heme: REV-ERBα and REV-ERBβ Are Ligand-Regulated Components of the Mammalian Clock

(2008) Thomas P. Burris   MOLECULAR ENDOCRINOLOGY