An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy

Detecting and Quantifying Changing Selection Intensities from Time-Sampled Polymorphism Data

(2016) Hyunjin Shim et al.   G3-Genes Genomes Genetics

Phosphorylation Controls the Nuclear-Cytoplasmic Shuttling of Influenza A Virus Nucleoprotein

(2015) Weinan Zheng et al.   JOURNAL OF VIROLOGY

Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin α Isoforms 3 and 7

(2015) Ruth A. Pumroy et al.   STRUCTURE

Evolutionary rescue: linking theory for conservation and medicine

(2014) Helen K. Alexander et al.   Evolutionary Applications

Influenza A Virus Polymerase Is a Site for Adaptive Changes during Experimental Evolution in Bat Cells

(2014) D. S. Poole et al.   JOURNAL OF VIROLOGY

WFABC: a Wright-Fisher ABC-based approach for inferring effective population sizes and selection coefficients from time-sampled data

(2014) Matthieu Foll et al.   Molecular Ecology Resources

Thinking too positive? Revisiting current methods of population genetic selection inference

(2014) Claudia Bank et al.   TRENDS IN GENETICS

Generation and characterization of influenza A viruses with altered polymerase fidelity

(2014) Peter P. H. Cheung et al.   Nature Communications

Influenza Virus Drug Resistance: A Time-Sampled Population Genetics Perspective

(2014) Matthieu Foll et al.   PLoS Genetics

Favipiravir elicits antiviral mutagenesis during virus replication in vivo

(2014) Armando Arias et al.   eLife

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Sialylneolacto-N-tetraose c (LSTc)-bearing Liposomal Decoys Capture Influenza A Virus

(2013) Gabriel L. Hendricks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of the Influenza A Virus Genome during Development of Oseltamivir Resistance In Vitro

(2013) N. Renzette et al.   JOURNAL OF VIROLOGY

T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro

(2013) T. Baranovich et al.   JOURNAL OF VIROLOGY

The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase

(2013) Zhinan Jin et al.   PLoS One

Approximate Bayesian Computation

(2013) Mikael Sunnåker et al.   PLoS Computational Biology

THE EVOLUTION OF STRESS-INDUCED HYPERMUTATION IN ASEXUAL POPULATIONS

(2012) Yoav Ram et al.   EVOLUTION

The Effects of Deleterious Mutations on Evolution at Linked Sites

(2012) Brian Charlesworth   GENETICS

Presence of Oseltamivir-Resistant Pandemic A/H1N1 Minor Variants Before Drug Therapy With Subsequent Selection and Transmission

(2012) Elodie Ghedin et al.   JOURNAL OF INFECTIOUS DISEASES

Enhanced Mammalian Transmissibility of Seasonal Influenza A/H1N1 Viruses Encoding an Oseltamivir-Resistant Neuraminidase

(2012) N. M. Bouvier et al.   JOURNAL OF VIROLOGY

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response

(2012) B. W. Jagger et al.   SCIENCE

Mutation Induced Extinction in Finite Populations: Lethal Mutagenesis and Lethal Isolation

(2012) C. Scott Wylie et al.   PLoS Computational Biology

Mapping the Phosphoproteome of Influenza A and B Viruses by Mass Spectrometry

(2012) Edward C. Hutchinson et al.   PLoS Pathogens

Amino Acid Changes in Hemagglutinin Contribute to the Replication of Oseltamivir-Resistant H1N1 Influenza Viruses

(2011) T. E. Ginting et al.   JOURNAL OF VIROLOGY

In Vitro Antiviral Activity of Favipiravir (T-705) against Drug-Resistant Influenza and 2009 A(H1N1) Viruses

(2010) K. Sleeman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

On measuring selection in experimental evolution

(2010) L.-M. Chevin   Biology Letters

Lethal mutagenesis and evolutionary epidemiology

(2010) G. Martin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

(2010) J. D. Bloom et al.   SCIENCE

Amino acid sequence analysis and identification of mutations under positive selection in hemagglutinin of 2009 influenza A (H1N1) isolates

(2010) Xiaofan Ding et al.   VIRUS GENES

Evolution at a High Imposed Mutation Rate: Adaptation Obscures the Load in Phage T7

(2009) R. Springman et al.   GENETICS

Global Transmission of Oseltamivir-Resistant Influenza

(2009) Anne Moscona   NEW ENGLAND JOURNAL OF MEDICINE

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

(2008) Patrick J. Collins et al.   NATURE