Gene duplications circumvent trade-offs in enzyme function: Insect adaptation to toxic host plants

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

(2016) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

How herbivores coopt plant defenses: natural selection, specialization, and sequestration

(2016) Georg Petschenka et al.   Current Opinion in Insect Science

Convergent adaptive evolution - how insects master the challenge of cardiac glycoside-containing host plants

(2015) Susanne Dobler et al.   ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA

Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex

(2015) Mette Laursen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Na+/K+-ATPase resistance and cardenolide sequestration: basal adaptations to host plant toxins in the milkweed bugs (Hemiptera: Lygaeidae: Lygaeinae)

(2015) C. Bramer et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Rapid incorporation of glucosinolates as a strategy used by a herbivore to prevent activation by myrosinases

(2014) Mohamed K. Abdalsamee et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Integrating Evolutionary and Functional Tests of Adaptive Hypotheses: A Case Study of Altitudinal Differentiation in Hemoglobin Function in an Andean Sparrow, Zonotrichia capensis

(2014) Zachary A. Cheviron et al.   MOLECULAR BIOLOGY AND EVOLUTION

STEPWISE EVOLUTION OF RESISTANCE TO TOXIC CARDENOLIDES VIA GENETIC SUBSTITUTIONS IN THE NA+/K+-ATPASE OF MILKWEED BUTTERFLIES (LEPIDOPTERA: DANAINI)

(2013) Georg Petschenka et al.   EVOLUTION

Amino acid substitutions of Na,K-ATPase conferring decreased sensitivity to cardenolides in insects compared to mammals

(2013) Safaa Dalla et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Repeated elevational transitions in hemoglobin function during the evolution of Andean hummingbirds

(2013) J. Projecto-Garcia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological screening for target site insensitivity and localization of Na+/K+-ATPase in cardenolide-adapted Lepidoptera

(2012) Georg Petschenka et al.   JOURNAL OF INSECT PHYSIOLOGY

Toxic cardenolides: chemical ecology and coevolution of specialized plant-herbivore interactions

(2012) Anurag A. Agrawal et al.   NEW PHYTOLOGIST

Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes

(2012) C. R. Feldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Community-wide convergent evolution in insect adaptation to toxic cardenolides by substitutions in the Na,K-ATPase

(2012) S. Dobler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene duplication as a mechanism of genomic adaptation to a changing environment

(2012) F. A. Kondrashov   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Parallel Molecular Evolution in an Herbivore Community

(2012) Y. Zhen et al.   SCIENCE

Evidence for a deterrent effect of cardenolides on Nephila spiders

(2011) Georg Petschenka et al.   BASIC AND APPLIED ECOLOGY

Coping with toxic plant compounds – The insect’s perspective on iridoid glycosides and cardenolides

(2011) Susanne Dobler et al.   PHYTOCHEMISTRY

Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase

(2010) Laure Yatime et al.   JOURNAL OF STRUCTURAL BIOLOGY

Flavin-Dependent Monooxygenases as a Detoxification Mechanism in Insects: New Insights from the Arctiids (Lepidoptera)

(2010) Sven Sehlmeyer et al.   PLoS One

Target-site sensitivity in a specialized herbivore towards major toxic compounds of its host plant: the Na+K+-ATPase of the oleander hawk moth (Daphnis nerii) is highly susceptible to cardenolides

(2009) Georg Petschenka et al.   CHEMOECOLOGY

Adaptive Evolution of Pelvic Reduction in Sticklebacks by Recurrent Deletion of a Pitx1 Enhancer

(2009) Y. F. Chan et al.   SCIENCE

Evolutionary Origins of a Novel Host Plant Detoxification Gene in Butterflies

(2008) Hanna M. Fischer et al.   MOLECULAR BIOLOGY AND EVOLUTION

β-Glucosidases as detonators of plant chemical defense

(2008) Anne Vinther Morant et al.   PHYTOCHEMISTRY