Multivalent Duplexed-Aptamer Networks Regulated a CRISPR-Cas12a System for Circulating Tumor Cell Detection

CRISPR-Cas systems for diagnosing infectious diseases

(2021) Anastasiya Kostyusheva et al.   METHODS

Universal and Naked-Eye Gene Detection Platform Based on the Clustered Regularly Interspaced Short Palindromic Repeats/Cas12a/13a System

(2020) Chaoqun Yuan et al.   ANALYTICAL CHEMISTRY

CRISPR/Cas12a-Mediated Interfacial Cleaving of Hairpin DNA Reporter for Electrochemical Nucleic Acid Sensing

(2020) Decai Zhang et al.   ACS Sensors

In Situ-Generated Multivalent Aptamer Network for Efficient Capture and Sensitive Electrochemical Detection of Circulating Tumor Cells in Whole Blood

(2020) Jianmei Yang et al.   ANALYTICAL CHEMISTRY

Applying CRISPR-Cas12a as a Signal Amplifier to Construct Biosensors for Non-DNA Targets in Ultralow Concentrations

(2020) Junjie Li et al.   ACS Sensors

Enzyme-Assisted Nucleic Acid Detection for Infectious Disease Diagnostics: Moving toward the Point-of-Care

(2020) Akkapol Suea-Ngam et al.   ACS Sensors

CRISPR/Cas Systems towards Next-Generation Biosensing

(2019) Yi Li et al.   TRENDS IN BIOTECHNOLOGY

RNA Strand Displacement Responsive CRISPR/Cas9 System for mRNA Sensing

(2019) Yue Li et al.   ANALYTICAL CHEMISTRY

Virus-Mimicking Cell Capture Using Heterovalency Magnetic DNA Nanoclaws

(2019) Zhiru Wang et al.   ACS Applied Materials & Interfaces

Electrochemical Detection of Circulating Tumor Cells Based on DNA Generated Electrochemical Current and Rolling Circle Amplification

(2019) Congcong Shen et al.   ANALYTICAL CHEMISTRY

Gold Nanoparticles-Based Multipedal DNA Walker for Ratiometric Detection of Circulating Tumor Cell

(2019) Peng Miao et al.   ANALYTICAL CHEMISTRY

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

(2019) Mindong Liang et al.   Nature Communications

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic-Acid Targets

(2019) Ying Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Comprehensive profiling of the ligand binding landscapes of duplexed aptamer families reveals widespread induced fit

(2018) Jeffrey D. Munzar et al.   Nature Communications

Strategies for Creating Structure-Switching Aptamers

(2018) Trevor A. Feagin et al.   ACS Sensors

Complementary oligonucleotides regulate induced fit ligand binding in duplexed aptamers

(2017) Jeffrey D. Munzar et al.   Chemical Science

Do Circulating Tumor Cells, Exosomes, and Circulating Tumor Nucleic Acids Have Clinical Utility?

(2015) Bert Gold et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Robust Nonenzymatic Hybrid Nanoelectrocatalysts for Signal Amplification toward Ultrasensitive Electrochemical Cytosensing

(2014) Tingting Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ICP-MS-Based Multiplex and Ultrasensitive Assay of Viruses with Lanthanide-Coded Biospecific Tagging and Amplification Strategies

(2013) Yacui Luo et al.   ANALYTICAL CHEMISTRY

Looking back, to the future of circulating tumor cells

(2013) Terence W. Friedlander et al.   PHARMACOLOGY & THERAPEUTICS

Bioinspired multivalent DNA network for capture and release of cells

(2012) W. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration

(2011) H. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells

(2008) Dihua Shangguan et al.   JOURNAL OF PROTEOME RESEARCH

Aptamer Switch Probe Based on Intramolecular Displacement

(2008) Zhiwen Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

(2008) Luciano A. Marraffini et al.   SCIENCE