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(2021) Barbara Blanco‐Fernandez et al.   Advanced Science

Rationally Programming Nanomaterials with DNA for Biomedical Applications

(2021) Liangcan He et al.   Advanced Science

Targeted drug delivery strategies for precision medicines

(2021) Mandana T. Manzari et al.   Nature Reviews Materials

Nuclease resistance of DNA nanostructures

(2021) Arun Richard Chandrasekaran   Nature Reviews Chemistry

Single-Cell Adenosine Triphosphate Content Monitoring during Hyperthermia Cell Death by Using Plasmonic Fluorescent Nanoflare

(2020) Ying Zhang et al.   ANALYTICAL CHEMISTRY

DNA Functional Materials Assembled from Branched DNA: Design, Synthesis, and Applications

(2020) Yuhang Dong et al.   CHEMICAL REVIEWS

Dual-acidity-labile polysaccharide-di-drugs conjugate for targeted cancer chemotherapy

(2020) Di Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Advances in oligonucleotide drug delivery

(2020) Thomas C. Roberts et al.   NATURE REVIEWS DRUG DISCOVERY

FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination

(2020) Elaine Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Applications and challenges of thermoplasmonics

(2020) Guillaume Baffou et al.   NATURE MATERIALS

DNA Nanostructures and DNA‐Functionalized Nanoparticles for Cancer Theranostics

(2020) Fay Nicolson et al.   Advanced Science

Nucleic Acid Based Constitutional Dynamic Networks: From Basic Principles to Applications

(2020) Liang Yue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

Discovery of Myricetin as a Potent Inhibitor of Human Flap Endonuclease 1, Which Potentially Can Be Used as Sensitizing Agent against HT-29 Human Colon Cancer Cells

(2019) Long Ma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Plasmonic Heating of Nanostructures

(2019) Liselotte Jauffred et al.   CHEMICAL REVIEWS

Nucleic‐Acid Structures as Intracellular Probes for Live Cells

(2019) Devleena Samanta et al.   ADVANCED MATERIALS

Signal Amplification in Living Cells: A Review of microRNA Detection and Imaging

(2019) Hanyong Peng et al.   ANALYTICAL CHEMISTRY

Rationally Engineered Nucleic Acid Architectures for Biosensing Applications

(2019) Mingshu Xiao et al.   CHEMICAL REVIEWS

Programming DNA Nanoassembly for Enhanced Photodynamic Therapy

(2019) Min Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Power of Spheres

(2019) Chad A. Mirkin et al.   NATURE

Nanomaterials for Cancer Precision Medicine

(2018) Yilong Wang et al.   ADVANCED MATERIALS

Overexpression of Flap Endonuclease 1 Correlates with Enhanced Proliferation and Poor Prognosis of Non–Small-Cell Lung Cancer

(2018) Keqiang Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Evaluating the Mechanisms of Light-Triggered siRNA Release from Nanoshells for Temporal Control Over Gene Regulation

(2018) Rachel S. Riley et al.   NANO LETTERS

Advances in nanotechnology for cancer biomarkers

(2018) Fei Ye et al.   Nano Today

Missed cleavage opportunities by FEN1 lead to Okazaki fragment maturation via the long-flap pathway

(2018) Manal S Zaher et al.   NUCLEIC ACIDS RESEARCH

Versatile Types of DNA-Based Nanobiosensors for Specific Detection of Cancer Biomarker FEN1 in Living Cells and Cell-Free Systems

(2018) Hao Zhang et al.   NANO LETTERS

Freezing Directed Construction of Bio/Nano Interfaces: Reagentless Conjugation, Denser Spherical Nucleic Acids, and Better Nanoflares

(2017) Biwu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual-stimuli responsive and reversibly activatable theranostic nanoprobe for precision tumor-targeting and fluorescence-guided photothermal therapy

(2017) Xu Zhao et al.   Nature Communications

Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability

(2017) Susan E. Tsutakawa et al.   Nature Communications

Advanced Functional Nanomaterials for Theranostics

(2016) Haoyuan Huang et al.   ADVANCED FUNCTIONAL MATERIALS

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Using DNA to program the self-assembly of colloidal nanoparticles and microparticles

(2016) W. Benjamin Rogers et al.   Nature Reviews Materials

Nanomaterials for Theranostics: Recent Advances and Future Challenges

(2014) Eun-Kyung Lim et al.   CHEMICAL REVIEWS

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer

(2014) Tarek M.A. Abdel-Fatah et al.   Molecular Oncology

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles

(2013) Borja Ballarín-González et al.   Molecular Therapy-Nucleic Acids

DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy

(2012) Zeyu Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

(2011) Susan E. Tsutakawa et al.   CELL

Functional regulation of FEN1 nuclease and its link to cancer

(2010) L. Zheng et al.   NUCLEIC ACIDS RESEARCH

Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity

(2010) Dorjbal Dorjsuren et al.   NUCLEIC ACIDS RESEARCH

Functional Nucleic Acid Sensors

(2009) Juewen Liu et al.   CHEMICAL REVIEWS