Simultaneous 3-Nitrophenylhydrazine Derivatization Strategy of Carbonyl, Carboxyl and Phosphoryl Submetabolome for LC-MS/MS-Based Targeted Metabolomics with Improved Sensitivity and Coverage

Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

(2021) Andrew W DeVilbiss et al.   eLife

Integrated cytokine and metabolite analysis reveals immunometabolic reprogramming in COVID-19 patients with therapeutic implications

(2021) Nan Xiao et al.   Nature Communications

Gluconeogenic enzyme PCK1 deficiency promotes CHK2 O-GlcNAcylation and hepatocellular carcinoma growth upon glucose deprivation

(2021) Jin Xiang et al.   JOURNAL OF CLINICAL INVESTIGATION

APOE alters glucose flux through central carbon pathways in astrocytes

(2020) Holden C. Williams et al.   NEUROBIOLOGY OF DISEASE

Chemical Discovery in the Era of Metabolomics

(2020) Miriam Sindelar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Automated parallel derivatization of metabolites with SWATH-MS data acquisition for qualitative and quantitative analysis

(2020) Maria Fernanda Cifuentes Girard et al.   ANALYTICA CHIMICA ACTA

Comprehensive Isotopic Targeted Mass Spectrometry: Reliable Metabolic Flux Analysis with Broad Coverage

(2020) Xiaojian Shi et al.   ANALYTICAL CHEMISTRY

Fast and sensitive flow-injection mass spectrometry metabolomics by analyzing sample-specific ion distributions

(2020) Boris Sarvin et al.   Nature Communications

On-Tissue Derivatization with Girard’s Reagent P Enhances N-Glycan Signals for Formalin-Fixed Paraffin-Embedded Tissue Sections in MALDI Mass Spectrometry Imaging

(2020) Hua Zhang et al.   ANALYTICAL CHEMISTRY

Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation

(2020) Ling Li et al.   MOLECULAR CELL

An exploratory approach for an oriented development of an untargeted hydrophilic interaction liquid chromatography-mass spectrometry platform for polar metabolites in biological matrices

(2020) Elias Iturrospe et al.   JOURNAL OF CHROMATOGRAPHY A

Derivatization-based sample-multiplexing for enhancing throughput in liquid chromatography/tandem mass spectrometry quantification of metabolites: an overview

(2020) Tatsuya Higashi et al.   JOURNAL OF CHROMATOGRAPHY A

Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC–MS/MS

(2019) Min Yuan et al.   Nature Protocols

Controlling Preanalytical Process in High-Coverage Quantitative Metabolomics: Spot-Sample Collection for Mouse Urine and Fecal Metabolome Profiling

(2019) Deying Chen et al.   ANALYTICAL CHEMISTRY

Metabolomic Coverage of Chemical-Group-Submetabolome Analysis: Group Classification and Four-Channel Chemical Isotope Labeling LC-MS

(2019) Shuang Zhao et al.   ANALYTICAL CHEMISTRY

Fine-Tuning of PGC1α Expression Regulates Cardiac Function and Longevity

(2019) Xudong Zhu et al.   CIRCULATION RESEARCH

High-resolution 13C metabolic flux analysis

(2019) Christopher P. Long et al.   Nature Protocols

Ion exchange in supercritical fluid chromatography tandem mass spectrometry (SFC-MS/MS): Application for polar and ionic drugs and metabolites in forensic and anti-doping analysis

(2019) Majlinda Xhaferaj et al.   JOURNAL OF CHROMATOGRAPHY A

Quantitative profiling of carbonyl metabolites directly in crude biological extracts using chemoselective tagging and nanoESI-FTMS

(2018) Pan Deng et al.   ANALYST

Isotope-labeling derivatization with 3-nitrophenylhydrazine for LC/multiple-reaction monitoring-mass-spectrometry-based quantitation of carnitines in dried blood spots

(2018) Jun Han et al.   ANALYTICA CHIMICA ACTA

Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers

(2018) Fang Huang et al.   Cell Metabolism

Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery

(2018) Dajana Vuckovic   CHEMICAL COMMUNICATIONS

Reverse engineering the cancer metabolic network using flux analysis to understand drivers of human disease

(2018) Mehmet G. Badur et al.   METABOLIC ENGINEERING

A chemical derivatization based UHPLC-LTQ-Orbitrap mass spectrometry method for accurate quantification of short-chain fatty acids in bronchoalveolar lavage fluid of asthma mice

(2018) Ying-Ying Jin et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Arginine deficiency is involved in thrombocytopenia and immunosuppression in severe fever with thrombocytopenia syndrome

(2018) Xiao-Kun Li et al.   Science Translational Medicine

Dansylhydrazine Isotope Labeling LC-MS for Comprehensive Carboxylic Acid Submetabolome Profiling

(2018) Shuang Zhao et al.   ANALYTICAL CHEMISTRY

Challenges, progress and promises of metabolite annotation for LC–MS-based metabolomics

(2018) Romanas Chaleckis et al.   CURRENT OPINION IN BIOTECHNOLOGY

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

(2017) Jiyeon Kim et al.   NATURE

Hypoxia induces heart regeneration in adult mice

(2017) Yuji Nakada et al.   NATURE

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

(2017) Michalis Agathocleous et al.   NATURE

Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation

(2017) Xin Liu et al.   NATURE CELL BIOLOGY

The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts

(2017) Xiaolei Shi et al.   Science Advances

Use of Ion Chromatography/Mass Spectrometry for Targeted Metabolite Profiling of Polar Organic Acids

(2016) Chris Petucci et al.   ANALYTICAL CHEMISTRY

Chemical Isotope Labeling LC-MS for High Coverage and Quantitative Profiling of the Hydroxyl Submetabolome in Metabolomics

(2016) Shuang Zhao et al.   ANALYTICAL CHEMISTRY

Quantitation of low molecular weight sugars by chemical derivatization-liquid chromatography/multiple reaction monitoring/mass spectrometry

(2016) Jun Han et al.   ELECTROPHORESIS

Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle

(2015) Tiago C. Alves et al.   Cell Metabolism

Oxidative stress inhibits distant metastasis by human melanoma cells

(2015) Elena Piskounova et al.   NATURE

NRF2 regulates serine biosynthesis in non–small cell lung cancer

(2015) Gina M DeNicola et al.   NATURE GENETICS

Integrated Quantification and Identification of Aldehydes and Ketones in Biological Samples

(2014) David Siegel et al.   ANALYTICAL CHEMISTRY

Quantification and Mass Isotopomer Profiling of α-Keto Acids in Central Carbon Metabolism

(2014) Michael Zimmermann et al.   ANALYTICAL CHEMISTRY

Inhibition of Cancer Cell Proliferation by PPARγ Is Mediated by a Metabolic Switch that Increases Reactive Oxygen Species Levels

(2014) Nishi Srivastava et al.   Cell Metabolism

Liquid–liquid extraction combined with differential isotope dimethylaminophenacyl labeling for improved metabolomic profiling of organic acids

(2013) Jun Peng et al.   ANALYTICA CHIMICA ACTA

Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

(2013) Keiyo Takubo et al.   Cell Stem Cell

Metabolomic analysis of key central carbon metabolism carboxylic acids as their 3-nitrophenylhydrazones by UPLC/ESI-MS

(2013) Jun Han et al.   ELECTROPHORESIS

The usefulness of hydrazine derivatives for mass spectrometric analysis of carbohydrates

(2013) Erika Lattová et al.   MASS SPECTROMETRY REVIEWS

IsoCor: correcting MS data in isotope labeling experiments

(2012) P. Millard et al.   BIOINFORMATICS

Quantitative Phosphorus Metabolomics Using Nanoflow Liquid Chromatography-Tandem Mass Spectrometry and Culture-Derived Comprehensive Global Internal Standards

(2009) Taisuke Uehara et al.   ANALYTICAL CHEMISTRY

Simultaneous Quantification of Metabolites Involved in Central Carbon and Energy Metabolism Using Reversed-Phase Liquid Chromatography−Mass Spectrometry and in Vitro13C Labeling

(2008) Wen-Chu Yang et al.   ANALYTICAL CHEMISTRY