Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC–MS/MS

A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source

(2017) Susanne B. Breitkopf et al.   Metabolomics

Serial-omics of P53−/−, Brca1−/− Mouse Breast Tumor and Normal Mammary Gland

(2017) Susanne B. Breitkopf et al.   Scientific Reports

Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton

(2016) Hai Hu et al.   CELL

Metabolic Heterogeneity in Human Lung Tumors

(2016) Christopher T. Hensley et al.   CELL

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer

(2016) Shawn M. Davidson et al.   Cell Metabolism

Optimal tracers for parallel labeling experiments and 13 C metabolic flux analysis: A new precision and synergy scoring system

(2016) Scott B. Crown et al.   METABOLIC ENGINEERING

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

(2016) Cristovão M. Sousa et al.   NATURE

Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer

(2016) Evan C. Lien et al.   NATURE CELL BIOLOGY

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

(2016) Andrew G. Cox et al.   NATURE CELL BIOLOGY

Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion

(2016) Ashish Juvekar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

(2016) I. Ben-Sahra et al.   SCIENCE

Triomics Analysis of Imatinib-Treated Myeloma Cells Connects Kinase Inhibition to RNA Processing and Decreased Lipid Biosynthesis

(2015) Susanne B. Breitkopf et al.   ANALYTICAL CHEMISTRY

Defining the Metabolome: Size, Flux, and Regulation

(2015) Nicola Zamboni et al.   MOLECULAR CELL

X13CMS: Global Tracking of Isotopic Labels in Untargeted Metabolomics

(2014) Xiaojing Huang et al.   ANALYTICAL CHEMISTRY

Visual workflows for 13 C-metabolic flux analysis

(2014) Katharina Nöh et al.   BIOINFORMATICS

Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

(2014) Tomoyuki Mashimo et al.   CELL

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

(2014) Andrea Viale et al.   NATURE

Loss of RBF1 changes glutamine catabolism

(2013) B. N. Nicolay et al.   GENES & DEVELOPMENT

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1

(2013) I. Ben-Sahra et al.   SCIENCE

Effects of a glucokinase activator on hepatic intermediary metabolism: study with13C-isotopomer-based metabolomics

(2012) Itzhak Nissim et al.   BIOCHEMICAL JOURNAL

13CFLUX2—high-performance software suite for 13C-metabolic flux analysis

(2012) Michael Weitzel et al.   BIOINFORMATICS

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

(2012) Min Yuan et al.   Nature Protocols

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

(2011) Jason W Locasale et al.   NATURE GENETICS

Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation

(2010) Jian-Bin Wang et al.   CANCER CELL

Novel biological insights through metabolomics and 13C-flux analysis

(2009) Nicola Zamboni et al.   CURRENT OPINION IN MICROBIOLOGY

Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells

(2009) Christian M. Metallo et al.   JOURNAL OF BIOTECHNOLOGY

13C-based metabolic flux analysis

(2009) Nicola Zamboni et al.   Nature Protocols