Bioorthogonal Chemical Signature Enabling Amplified Visualization of Cellular Oxidative Thymines

Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications

(2021) Feng Chen et al.   Nature Communications

Differentiated Visualization of Single-Cell 5-Hydroxymethylpyrimidines with Microfluidic Hydrogel Encoding

(2020) Feng Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA 5-Methylcytosine-Specific Amplification and Sequencing

(2020) Chang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mapping the epigenetic modifications of DNA and RNA

(2020) Lin-Yong Zhao et al.   Protein & Cell

Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution

(2019) Yibin Liu et al.   NATURE BIOTECHNOLOGY

Detection, Structure and Function of Modified DNA Bases

(2019) Alexandre Hofer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA Splicing Analysis: From In Vitro Testing to Single-Cell Imaging

(2019) Xiaojun Ren et al.   Chem

Sequencing 5-Hydroxymethyluracil at Single-Base Resolution

(2018) Fumiko Kawasaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Hierarchical Coding Strategy for Live Cell Imaging of Protein-Specific Glycoform

(2018) Siqiao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase

(2018) Emily K Schutsky et al.   NATURE BIOTECHNOLOGY

Methods for detection of cytosine and thymine modifications in DNA

(2018) Mark Berney et al.   Nature Reviews Chemistry

Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA

(2016) Martyna Modrzejewska et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enigmatic 5-hydroxymethyluracil: Oxidatively modified base, epigenetic mark or both?

(2016) Ryszard Olinski et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Self-assembly of nucleic acid molecular aggregates catalyzed by a triple-helix probe for miRNA detection and single cell imaging

(2016) Zhen Zhang et al.   Chemical Science

Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale

(2015) Bo Xia et al.   NATURE METHODS

A Highly Sensitive Target-Primed Rolling Circle Amplification (TPRCA) Method for Fluorescent in Situ Hybridization Detection of MicroRNA in Tumor Cells

(2014) Jia Ge et al.   ANALYTICAL CHEMISTRY

Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA

(2014) Toni Pfaffeneder et al.   Nature Chemical Biology

5-Hydroxymethylcytosine is a predominantly stable DNA modification

(2014) Martin Bachman et al.   Nature Chemistry

Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution

(2014) Michael J. Booth et al.   Nature Chemistry

Synthesis of γ-labeled nucleoside 5′-triphosphates using click chemistry

(2013) S. Serdjukow et al.   CHEMICAL COMMUNICATIONS

Noncanonical Self-Assembly of Multifunctional DNA Nanoflowers for Biomedical Applications

(2013) Guizhi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA

(2013) Shuo Liu et al.   NUCLEIC ACIDS RESEARCH

Synthesis and Stability of Phosphate Modified ATP Analogues

(2012) Stephan M. Hacker et al.   JOURNAL OF ORGANIC CHEMISTRY

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE