Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase

Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome

(2017) Brian S Johnson et al.   NATURE MEDICINE

APOBEC3A efficiently deaminates methylated, but not TET-oxidized, cytosine bases in DNA

(2017) Emily K. Schutsky et al.   NUCLEIC ACIDS RESEARCH

5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes

(2017) Marian Mellén et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex

(2017) Chongyuan Luo et al.   SCIENCE

Impact of cytosine methylation on DNA binding specificities of human transcription factors

(2017) Yimeng Yin et al.   SCIENCE

Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases

(2016) Sachini U. Siriwardena et al.   CHEMICAL REVIEWS

Quantifying mammalian genomic DNA hydroxymethylcytosine content using solid-state nanopores

(2016) Osama K. Zahid et al.   Scientific Reports

Age-Dependent Levels of 5-Methyl-, 5-Hydroxymethyl-, and 5-Formylcytosine in Human and Mouse Brain Tissues

(2015) Mirko Wagner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution

(2015) Jeffrey A. Gross et al.   BMC GENOMICS

A Sensitive Approach to Map Genome-wide 5-Hydroxymethylcytosine and 5-Formylcytosine at Single-Base Resolution

(2015) Zhiyi Sun et al.   MOLECULAR CELL

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

(2015) Harrison W. Gabel et al.   NATURE

Function and information content of DNA methylation

(2015) Dirk Schübeler   NATURE

5-Formylcytosine can be a stable DNA modification in mammals

(2015) Martin Bachman et al.   Nature Chemical Biology

Structural characterization of human heparanase reveals insights into substrate recognition

(2015) Liang Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain

(2015) Alisa Mo et al.   NEURON

Covalent Modification of Bacteriophage T4 DNA Inhibits CRISPR-Cas9

(2015) Alexandra L. Bryson et al.   mBio

Structural characterization of human heparanase reveals insights into substrate recognition

(2015) Liang Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chemical Methods for Decoding Cytosine Modifications in DNA

(2014) Michael J. Booth et al.   CHEMICAL REVIEWS

Role of Tet proteins in enhancer activity and telomere elongation

(2014) Falong Lu et al.   GENES & DEVELOPMENT

Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing

(2014) Hao Wu et al.   NATURE BIOTECHNOLOGY

5-Hydroxymethylcytosine is a predominantly stable DNA modification

(2014) Martin Bachman et al.   Nature Chemistry

Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases inCoprinopsis cinerea

(2014) Lukas Chavez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MLML: consistent simultaneous estimates of DNA methylation and hydroxymethylation

(2013) Jianghan Qu et al.   BIOINFORMATICS

Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation

(2013) Lulu Hu et al.   CELL

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics

(2013) Li Shen et al.   CELL

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

High-Resolution Enzymatic Mapping of Genomic 5-Hydroxymethylcytosine in Mouse Embryonic Stem Cells

(2013) Zhiyi Sun et al.   Cell Reports

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Base-Resolution Analyses of Sequence and Parent-of-Origin Dependent DNA Methylation in the Mouse Genome

(2012) Wei Xie et al.   CELL

Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome

(2012) Miao Yu et al.   CELL

Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3A

(2012) Michael A. Carpenter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation

(2012) Christopher S Nabel et al.   Nature Chemical Biology

Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G

(2012) Priyanga Wijesinghe et al.   NUCLEIC ACIDS RESEARCH

Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution

(2012) M. J. Booth et al.   SCIENCE

The Discovery of 5-Formylcytosine in Embryonic Stem Cell DNA

(2011) Toni Pfaffeneder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

(2011) Felix Krueger et al.   BIOINFORMATICS

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

(2011) Y.-F. He et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

(2010) Yun Huang et al.   PLoS One

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Real-Time DNA Sequencing from Single Polymerase Molecules

(2008) J. Eid et al.   SCIENCE