Experimental rhinovirus infection induces an antiviral response in circulating B cells which is dysregulated in patients with asthma

T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection

(2020) Jacob D. Eccles et al.   Cell Reports

M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations

(2020) Alexandra Nikonova et al.   EBioMedicine

Increased antiviral response in circulating lymphocytes from hypogammaglobulinemia patients

(2020) Oliver F. Wirz et al.   ALLERGY

Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children

(2019) Matthew C. Altman et al.   NATURE IMMUNOLOGY

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

(2019) Paulina Mrozek-Gorska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NOVEL FUNCTIONS OF THE INTERFERON-INDUCED PROTEIN 44-LIKE (IFI44L) AS A FEEDBACK REGULATOR OF HOST ANTIVIRAL RESPONSES

(2019) Marta L. DeDiego et al.   JOURNAL OF VIROLOGY

Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations

(2018) Jie Zhu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza

(2018) Jake Dunning et al.   NATURE IMMUNOLOGY

B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen

(2018) Sheng Hong et al.   IMMUNITY

Virus-inclusive single-cell RNA sequencing reveals the molecular signature of progression to severe dengue

(2018) Fabio Zanini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity

(2017) Dania Zhivaki et al.   IMMUNITY

Rhinovirus infection results in stronger and more persistent genomic dysregulation: Evidence for altered innate immune response in asthmatics at baseline, early in infection, and during convalescence

(2017) Peter W. Heymann et al.   PLoS One

A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13)

(2017) Trevor T. Hansel et al.   EBioMedicine

Human rhinoviruses enter and induce proliferation of B lymphocytes

(2016) A. Aab et al.   ALLERGY

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Rhinovirus-induced VP1-specific Antibodies are Group-specific and Associated With Severity of Respiratory Symptoms

(2015) Katarzyna Niespodziana et al.   EBioMedicine

Distinct regulation of tonsillar immune response in virus infection

(2014) T. Jartti et al.   ALLERGY

IL-33–Dependent Type 2 Inflammation during Rhinovirus-induced Asthma ExacerbationsIn Vivo

(2014) David J. Jackson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

B-lymphocyte lineage cells and the respiratory system

(2013) Atsushi Kato et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus

(2013) Stephanie K. Dougan et al.   NATURE

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1

(2012) Alex Karnowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax

(2012) M Rayamajhi et al.   Mucosal Immunology

INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

(2012) Irina Rusinova et al.   NUCLEIC ACIDS RESEARCH

Detecting Respiratory Viruses in Asymptomatic Children

(2012) Sonali Advani et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Low-affinity B cells transport viral particles from the lung to the spleen to initiate antibody responses

(2012) J. Bessa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Misdirected antibody responses against an N-terminal epitope on human rhinovirus VP1 as explanation for recurrent RV infections

(2011) Katarzyna Niespodziana et al.   FASEB JOURNAL

Host and viral factors associated with severity of human rhinovirus–associated infant respiratory tract illness

(2011) E. Kathryn Miller et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance

(2011) Oscar Palomares et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IFN-α produced by human plasmacytoid dendritic cells enhances T cell-dependent naïve B cell differentiation

(2011) Cornelia Gujer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection

(2011) J. A. Harker et al.   SCIENCE

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus

(2011) I-Chueh Huang et al.   PLoS Pathogens

B Cell-Derived Vascular Endothelial Growth Factor A Promotes Lymphangiogenesis and High Endothelial Venule Expansion in Lymph Nodes

(2010) B. Shrestha et al.   JOURNAL OF IMMUNOLOGY

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interferon-Induced Cell Membrane Proteins, IFITM3 and Tetherin, Inhibit Vesicular Stomatitis Virus Infection via Distinct Mechanisms

(2010) J. M. Weidner et al.   JOURNAL OF VIROLOGY

The ISG15 Conjugation System Broadly Targets Newly Synthesized Proteins: Implications for the Antiviral Function of ISG15

(2010) Larissa A. Durfee et al.   MOLECULAR CELL

Induction of type I interferon by RNA viruses: cellular receptors and their substrates

(2009) Alina Baum et al.   AMINO ACIDS

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

Gene Expression Signatures Diagnose Influenza and Other Symptomatic Respiratory Viral Infections in Humans

(2009) Aimee K. Zaas et al.   Cell Host & Microbe

The ssRNA Genome of Human Rhinovirus Induces a Type I IFN Response but Fails to Induce Maturation in Human Monocyte-Derived Dendritic Cells

(2009) C. Schrauf et al.   JOURNAL OF IMMUNOLOGY

IFN-α amplifies human naïve B cell TLR-9-mediated activation and Ig production

(2009) L. Giordani et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Wheezing Rhinovirus Illnesses in Early Life Predict Asthma Development in High-Risk Children

(2008) Daniel J. Jackson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Respiratory Pathogens in Children with and without Respiratory Symptoms

(2008) Marieke M. van der Zalm et al.   JOURNAL OF PEDIATRICS

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

(2008) S. D. Message et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA