Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility

Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet–Induced Obese Mice

(2020) Xiaodong Sun et al.   DIABETES

Myocardial Contractility: Historical and Contemporary Considerations

(2020) William W. Muir et al.   Frontiers in Physiology

SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion

(2020) Ying Han et al.   Redox Biology

Inhibition Of Mitochondrial Calcium Overload By SIRT3 Prevents Obesity Or Age-Related Whitening Of Brown Adipose Tissue

(2019) Peng Gao et al.   DIABETES

The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury

(2019) Kuznetsov et al.   Antioxidants

Empagliflozin attenuates ischemia and reperfusion injury through LKB1/AMPK signaling pathway

(2019) Qingguo Lu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cardiomyocyte-specific deletion of Sirt1 gene sensitizes myocardium to ischaemia and reperfusion injury

(2018) Lin Wang et al.   CARDIOVASCULAR RESEARCH

OXPHOS Defects Due to mtDNA Mutations: Glutamine to the Rescue!

(2018) Christos Chinopoulos   Cell Metabolism

SIRT3: A New Regulator of Cardiovascular Diseases

(2018) Wei Sun et al.   Oxidative Medicine and Cellular Longevity

Acetylation of Mitochondrial Proteins in the Heart: The Role of SIRT3

(2018) Rebecca M. Parodi-Rullán et al.   Frontiers in Physiology

Dichloroacetate Ameliorates Cardiac Dysfunction Caused by Ischemic Insults Through AMPK Signal Pathway—Not Only Shifts Metabolism

(2018) Xuan Li et al.   TOXICOLOGICAL SCIENCES

SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy

(2018) Wenyu Zhao et al.   Frontiers in Physiology

Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury

(2017) Chayodom Maneechote et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

High Sensitivity of SIRT3 Deficient Hearts to Ischemia-Reperfusion Is Associated with Mitochondrial Abnormalities

(2017) Rebecca M. Parodi-Rullán et al.   Frontiers in Pharmacology

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

(2016) Lena Pernas et al.   Annual Review of Physiology

AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia

(2016) Vlad G. Zaha et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial dynamics, mitophagy and cardiovascular disease

(2016) César Vásquez-Trincado et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sirtuin 3 (SIRT3) maintains bone homeostasis by regulating AMPK-PGC-1β axis in mice

(2016) Jeong-Eun Huh et al.   Scientific Reports

Mitochondrial dynamism and heart disease: changing shape and shaping change

(2015) G. W. Dorn   EMBO Molecular Medicine

SIRT3 Deacetylates Ceramide Synthases

(2015) Sergei A. Novgorodov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts

(2014) George A. Porter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage

(2013) Anne H.H. Tseng et al.   FREE RADICAL BIOLOGY AND MEDICINE

SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress

(2013) Sadhana A. Samant et al.   MOLECULAR AND CELLULAR BIOLOGY

Impaired Cardiac SIRT1 Activity by Carbonyl Stress Contributes to Aging-Related Ischemic Intolerance

(2013) Chunhu Gu et al.   PLoS One

Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca 2+ Crosstalk

(2012) Yun Chen et al.   CIRCULATION RESEARCH

Impaired SIRT1 nucleocytoplasmic shuttling in the senescent heart during ischemic stress

(2012) Chao Tong et al.   FASEB JOURNAL

Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death

(2011) Kyriakos N. Papanicolaou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes

(2011) K. N. Papanicolaou et al.   MOLECULAR AND CELLULAR BIOLOGY

AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction

(2010) Subat Turdi et al.   AGING CELL

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

(2010) Shin-ichiro Imai et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Effect of age on cardiac excitation-contraction coupling

(2009) Elias Fares et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Sirtuins — novel therapeutic targets to treat age-associated diseases

(2008) Siva Lavu et al.   NATURE REVIEWS DRUG DISCOVERY