Impaired SIRT1 nucleocytoplasmic shuttling in the senescent heart during ischemic stress

Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice

(2011) Alex Morrison et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction

(2011) Eun Young Kim et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Activated protein C protects against myocardial ischemic/reperfusion injury through AMP-activated protein kinase signaling

(2011) J. WANG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway

(2011) Eddie D. Yeung et al.   PROSTATE

Impaired Macrophage Migration Inhibitory Factor–AMP-Activated Protein Kinase Activation and Ischemic Recovery in the Senescent Heart

(2010) Heng Ma et al.   CIRCULATION

Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion

(2010) Chiao-Po Hsu et al.   CIRCULATION

Sumoylation and Regulation of Cardiac Gene Expression

(2010) Jun Wang et al.   CIRCULATION RESEARCH

Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/−Mice: A Role of Lipid Mobilization and Inflammation

(2010) Fen Xu et al.   ENDOCRINOLOGY

Overnutrition and maternal obesity in sheep pregnancy alter the JNK-IRS-1 signaling cascades and cardiac function in the fetal heart

(2010) Jingying Wang et al.   FASEB JOURNAL

Ubiquitin/SUMO Modification Regulates VHL Protein Stability and Nucleocytoplasmic Localization

(2010) Qiliang Cai et al.   PLoS One

Macrophage migration inhibitory factor deficiency augments cardiac dysfunction in Type 1 diabetic murine cardiomyocytes

(2010) Chao TONG et al.   Journal of Diabetes

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

(2009) Jesse J Smith et al.   BMC Systems Biology

Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate

(2009) Isao Fukuda et al.   CHEMISTRY & BIOLOGY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol

(2009) G Boily et al.   ONCOGENE

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

(2008) Marcella Fulco et al.   DEVELOPMENTAL CELL

Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats

(2008) Jeng-Feng Lin et al.   LIFE SCIENCES

Aging and dietary restriction effects on ubiquitination, sumoylation, and the proteasome in the heart

(2008) Feng Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart

(2008) Edward J. Miller et al.   NATURE