Spherical Nucleic Acids for Near-Infrared Light-Responsive Self-Delivery of Small-Interfering RNA and Antisense Oligonucleotide

Carrier-Free Hybrid DNA Nanoparticles for Light-Induced Self-Delivery of Functional Nucleic Acid Enzymes

(2021) Leilei Shi et al.   ACS Nano

Spherical Nucleic Acids for Topical Treatment of Hyperpigmentation

(2021) Yang Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hybrid Nanospheres to Overcome Hypoxia and Intrinsic Oxidative Resistance for Enhanced Photodynamic Therapy

(2020) Leilei Shi et al.   ACS Nano

Smart magnetofluorogenic photosensitizer nanoassemblies enabling redox‐driven disassembly for photodynamic therapy

(2020) Ruibing An et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light Induced Self‐Escape of Spherical Nucleic Acid from Endo/Lysosome for Efficient Non‐Cationic Gene Delivery

(2020) Leilei Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carrier‐Free Delivery of Precise Drug–Chemogene Conjugates for Synergistic Treatment of Drug‐Resistant Cancer

(2020) Lijuan Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in oligonucleotide drug delivery

(2020) Thomas C. Roberts et al.   NATURE REVIEWS DRUG DISCOVERY

Switching the intracellular pathway and enhancing the therapeutic efficacy of small interfering RNA by auroliposome

(2020) Md. Nazir Hossen et al.   Science Advances

Carrier-free nanodrugs for safe and effective cancer treatment

(2020) Sena Karaosmanoglu et al.   JOURNAL OF CONTROLLED RELEASE

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

The current state and future directions of RNAi-based therapeutics

(2019) Ryan L. Setten et al.   NATURE REVIEWS DRUG DISCOVERY

The siRNAsome: A Cation-Free and Versatile Nanostructure for siRNA and Drug Co-delivery

(2019) Meng Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled and Size-Controllable Oligonucleotide Nanospheres for Effective Antisense Gene Delivery through an Endocytosis-Independent Pathway

(2019) Jie Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Theranostic Nanoparticles for RNA-Based Cancer Treatment

(2019) Richard A. Revia et al.   ACCOUNTS OF CHEMICAL RESEARCH

Two-in-One Chemogene Assembled from Drug-Integrated Antisense Oligonucleotides To Reverse Chemoresistance

(2019) Quanbing Mou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic Semiconducting Pro-nanostimulants for Near-Infrared Photoactivatable Cancer Immunotherapy

(2019) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting mRNA processing as an anticancer strategy

(2019) Joana Desterro et al.   NATURE REVIEWS DRUG DISCOVERY

Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics

(2019) Jacques Saarbach et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Self-Amplified Photodynamic Therapy through the 1 O2 -Mediated Internalization of Photosensitizers from a Ppa-Bearing Block Copolymer

(2019) Zhiyong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Programming DNA Nanoassembly for Enhanced Photodynamic Therapy

(2019) Min Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

(2019) Akin Akinc et al.   Nature Nanotechnology

Engineering Multifunctional RNAi Nanomedicine To Concurrently Target Cancer Hallmarks for Combinatorial Therapy

(2018) Yanlan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

(2018) David Adams et al.   NEW ENGLAND JOURNAL OF MEDICINE

Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs

(2018) Owen S. Fenton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy

(2018) Yiwen Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Blurring the Role of Oligonucleotides: Spherical Nucleic Acids as a Drug Delivery Vehicle

(2016) Xuyu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancer

(2015) Wei-Hua Chen et al.   CANCER LETTERS

Clinical experiences with systemically administered siRNA-based therapeutics in cancer

(2015) Jonathan E. Zuckerman et al.   NATURE REVIEWS DRUG DISCOVERY

Programmable materials and the nature of the DNA bond

(2015) M. R. Jones et al.   SCIENCE

Intracellular mRNA Regulation with Self-Assembled Locked Nucleic Acid Polymer Nanoparticles

(2014) Anthony M. Rush et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

(2014) Jayaprakash K. Nair et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications

(2014) Bryan R Meade et al.   NATURE BIOTECHNOLOGY

Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates

(2013) C. H. J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spherical Nucleic Acids

(2012) Joshua I. Cutler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY