Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Alkynyl Phosphonate DNA: A Versatile “Click”able Backbone for DNA-Based Biological Applications

(2012) Heera Krishna et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein transduction domain delivery of therapeutic macromolecules

(2011) Arjen van den Berg et al.   CURRENT OPINION IN BIOTECHNOLOGY

Progress Toward In Vivo Use of siRNAs-II

(2011) Garrett R Rettig et al.   MOLECULAR THERAPY

Current prospects for RNA interference-based therapies

(2011) Beverly L. Davidson et al.   NATURE REVIEWS GENETICS

Reversible modification of oligodeoxynucleotides: click reaction at phosphate group and alkali treatment

(2011) Kazuhito Tanabe et al.   TETRAHEDRON LETTERS

Silencing or Stimulation? siRNA Delivery and the Immune System

(2011) Kathryn A. Whitehead et al.   Annual Review of Chemical and Biomolecular Engineering

Ancestral Roles of Small RNAs: An Ago-Centric Perspective

(2010) L. Joshua-Tor et al.   Cold Spring Harbor Perspectives in Biology

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

(2009) Kent S. Gates   CHEMICAL RESEARCH IN TOXICOLOGY

The Effect of Chemical Modification and Nanoparticle Formulation on Stability and Biodistribution of siRNA in Mice

(2009) Shan Gao et al.   MOLECULAR THERAPY

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein

(2009) Akiko Eguchi et al.   NATURE BIOTECHNOLOGY

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

Chemical Modification of siRNAs for In Vivo Use

(2008) Mark A. Behlke   OLIGONUCLEOTIDES