Paracetamol-Induced Glutathione Consumption: Is There a Link With Severe COVID-19 Illness?

Increased sFLT1/PlGF ratio in COVID‐19: a novel link to Angiotensin II‐mediated endothelial dysfunction

(2020) Valentina Giardini et al.   AMERICAN JOURNAL OF HEMATOLOGY

COVID-19 and Avoiding Ibuprofen. How Good Is the Evidence?

(2020) Gurusaravanan Kutti Sridharan et al.   AMERICAN JOURNAL OF THERAPEUTICS

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

(2020) Paolo Verdecchia et al.   European Journal of Internal Medicine

COVID-19 illness in native and immunosuppressed states: A clinical–therapeutic staging proposal

(2020) Hasan K. Siddiqi et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

COVID-19 pandemic and therapy with ibuprofen or renin-angiotensin system blockers: no need for interruptions or changes in ongoing chronic treatments

(2020) Oliver Zolk et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Misguided drug advice for COVID-19

(2020) Garret A. FitzGerald   SCIENCE

Non-steroidal anti-inflammatory drugs, pharmacology, and COVID-19 infection

(2020) Joëlle Micallef et al.   THERAPIE

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths

(2020) William B. Grant et al.   Nutrients

Covid-19: ibuprofen should not be used for managing symptoms, say doctors and scientists

(2020) Michael Day   BMJ-British Medical Journal

Is glucose-6-phosphate dehydrogenase enzyme deficiency a factor in Coronavirus-19 (COVID-19) infections and deaths?

(2020) Duygu Aydemir et al.   Pathogens and Global Health

Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients

(2020) Alexey Polonikov   ACS Infectious Diseases

Does Ibuprofen Worsen COVID-19?

(2020) Nicholas Moore et al.   DRUG SAFETY

Rationale for the use of N -acetylcysteine in both prevention and adjuvant therapy of COVID-19

(2020) Silvio De Flora et al.   FASEB JOURNAL

Renin-Angiotensin System Blockers and the COVID-19 Pandemic

(2020) A.H. Jan Danser et al.   HYPERTENSION

No current evidence supporting risk of using Ibuprofen in patients with COVID‐19

(2020) Paulo Ricardo Martins‐Filho et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Combination of four clinical indicators predicts the severe/critical symptom of patients infected COVID-19

(2020) Liping Sun et al.   JOURNAL OF CLINICAL VIROLOGY

COVID-19 and Liver

(2020) Dinesh Jothimani et al.   JOURNAL OF HEPATOLOGY

COVID-19 and the kidney: what we think we know so far and what we don’t

(2020) Samira S. Farouk et al.   JOURNAL OF NEPHROLOGY

Can Vitamin D and L-Cysteine Co-Supplementation Reduce 25(OH)-Vitamin D Deficiency and the Mortality Associated with COVID-19 in African Americans?

(2020) Sushil K. Jain et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

NSAIDs in patients with viral infections, including Covid-19: Victims or perpetrators?

(2020) Annalisa Capuano et al.   PHARMACOLOGICAL RESEARCH

NSAIDs may increase the risk of thrombosis and acute renal failure in patients with COVID-19 infection

(2020) Medine Cumhur Cure et al.   THERAPIE

COVID-19 and NSAIDs: Primum non nocere

(2020) Joëlle Micallef et al.   THERAPIE

Repositioning Chromones for Early Anti-inflammatory Treatment of COVID-19

(2020) Piero Sestili et al.   Frontiers in Pharmacology

Prior Routine Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Important Outcomes in Hospitalised Patients with COVID-19

(2020) Eilidh Bruce et al.   Journal of Clinical Medicine

Relationship Between COVID-19 Infection and Liver Injury: A Review of Recent Data

(2020) Nurshad Ali   Frontiers in Medicine

Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature

(2020) Nicola Veronese et al.   Frontiers in Medicine

Impact of Thiol–Disulfide Balance on the Binding of Covid-19 Spike Protein with Angiotensin-Converting Enzyme 2 Receptor

(2020) Sanchita Hati et al.   ACS Omega

The COVID‐19 ibuprofen controversy: A systematic review of NSAIDs in adult acute lower respiratory tract infections

(2020) Ricky Vaja et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

An evidence for correlation between the glutathione S-transferase T1 (GSTT1) polymorphism and outcome of COVID-19

(2020) Mostafa Saadat   CLINICA CHIMICA ACTA

Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine

(2020) Homam Ibrahim et al.   CLINICAL IMMUNOLOGY

A narrative review of the potential pharmacological influence and safety of ibuprofen on coronavirus disease 19 (COVID-19), ACE2, and the immune system: a dichotomy of expectation and reality

(2020) Lucinda Smart et al.   INFLAMMOPHARMACOLOGY

Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results

(2020) David O. Meltzer et al.   JAMA Network Open

Impact of medication on protein and amino acid metabolism in the elderly: the sulfur amino acid and paracetamol case

(2018) Carole Mast et al.   NUTRITION RESEARCH REVIEWS

Redox Biology of Respiratory Viral Infections

(2018) Olga Khomich et al.   Viruses-Basel

Therapeutic Modulation of Virus-Induced Oxidative Stress via the Nrf2-Dependent Antioxidative Pathway

(2018) Choongho Lee   Oxidative Medicine and Cellular Longevity

Host-directed therapies for bacterial and viral infections

(2017) Stefan H. E. Kaufmann et al.   NATURE REVIEWS DRUG DISCOVERY

Paracetamol: not as safe as we thought? A systematic literature review of observational studies

(2015) Emmert Roberts et al.   ANNALS OF THE RHEUMATIC DISEASES

A quantum chemical study of the reactivity of acetaminophen (paracetamol) toxic metabolite N-acetyl-p-benzoquinone imine with deoxyguanosine and glutathione

(2015) Ivana Klopčič et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Application of Glutathione as Anti-Oxidative and Anti-Aging Drugs

(2015) Takujiro Homma et al.   CURRENT DRUG METABOLISM

Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels in the blood of type 2 diabetic patients

(2014) S K Jain et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Acetaminophen/paracetamol: A history of errors, failures and false decisions

(2014) K. Brune et al.   EUROPEAN JOURNAL OF PAIN

Risks of nonsteroidal antiinflammatory drugs in undiagnosed intensive care unit pneumococcal pneumonia: Younger and more severely affected patients

(2014) Jonathan Messika et al.   JOURNAL OF CRITICAL CARE

Comparison of inhibitory effects between acetaminophen-glutathione conjugate and reduced glutathione in human glutathione reductase

(2013) Erika Nýdlová et al.   JOURNAL OF APPLIED TOXICOLOGY

Therapeutic paracetamol treatment in older persons induces dietary and metabolic modifications related to sulfur amino acids

(2011) Estelle Pujos-Guillot et al.   AGE

The Association of Acetaminophen and Asthma Prevalence and Severity

(2011) J. T. McBride   PEDIATRICS