Protein-Mimicking Nanoparticles for a Cellular Regulation of Homeostasis

A Tauopathy-Homing and Autophagy-Activating Nanoassembly for Specific Clearance of Pathogenic Tau in Alzheimer’s Disease

(2021) Heng Sun et al.   ACS Nano

Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics

(2021) Qinjie Weng et al.   Nature Communications

Cell Surface Engineering Using DNAzymes: Metal Ion Mediated Control of Cell–Cell Interactions

(2021) Ruo-Can Qian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Treating Acute Kidney Injury with Antioxidative Black Phosphorus Nanosheets

(2020) Junjun Hou et al.   NANO LETTERS

Biomimetic Presentation of Cryptic Ligands via Single-Chain Nanogels for Synergistic Regulation of Stem Cells

(2020) Xiaoyu Chen et al.   ACS Nano

Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity

(2020) Lin Hou et al.   ACS Nano

Programming Cell–Cell Communications with Engineered Cell Origami Clusters

(2020) Zhilei Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases

(2020) Tengfei Liu et al.   Nature Communications

An Organelle‐Specific Nanozyme for Diabetes Care in Genetically or Diet‐Induced Models

(2020) Yanfeng Zhou et al.   ADVANCED MATERIALS

Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

(2020) Liyang Cui et al.   NATURE BIOTECHNOLOGY

Dual detoxification and inflammatory regulation by ceria nanozymes for drug-induced liver injury therapy

(2020) Fangyuan Li et al.   Nano Today

FDA-approved ferumoxytol displays anti-leukaemia efficacy against cells with low ferroportin levels

(2019) Vicenta Trujillo-Alonso et al.   Nature Nanotechnology

Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness

(2019) Fei Peng et al.   Nature Nanotechnology

Conformational manipulation of scale-up prepared single-chain polymeric nanogels for multiscale regulation of cells

(2019) Xiaoyu Chen et al.   Nature Communications

NaCl Nanoparticles as a Cancer Therapeutic

(2019) Wen Jiang et al.   ADVANCED MATERIALS

MnFe2O4 nanoparticles accelerate the clearance of mutant huntingtin selectively through ubiquitin-proteasome system

(2019) Li Zhang et al.   BIOMATERIALS

Inhibition of Epithelial–Mesenchymal Transition and Tissue Regeneration by Waterborne Titanium Dioxide Nanoparticles

(2018) Xiaojiao Li et al.   ACS Applied Materials & Interfaces

Highly Fluorescent Chiral N-S-Doped Carbon Dots from Cysteine: Affecting Cellular Energy Metabolism

(2018) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

(2018) Chenguang Wang et al.   IMMUNITY

Inorganic Nanomaterials as Highly Efficient Inhibitors of Cellular Hepatic Fibrosis

(2018) Fei Peng et al.   ACS Applied Materials & Interfaces

Crumpled Aluminum Hydroxide Nanostructures as a Microenvironment Dysregulation Agent for Cancer Treatment

(2018) Marat I. Lerner et al.   NANO LETTERS

Nanodiamond-based non-canonical autophagy inhibitor synergistically induces cell death in oxygen-deprived tumors

(2018) Nan Chen et al.   Materials Horizons

Programming Niche Accessibility and In Vitro Stemness with Intercellular DNA Reactions

(2018) Xiaojiao Li et al.   ADVANCED MATERIALS

Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia

(2018) Yifei Lu et al.   Advanced Science

DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury

(2018) Dawei Jiang et al.   Nature Biomedical Engineering

Titania-Coated Gold Nano-Bipyramids for Blocking Autophagy Flux and Sensitizing Cancer Cells to Proteasome Inhibitor-Induced Death

(2017) Hong-Ye Wan et al.   Advanced Science

A non-cytotoxic dendrimer with innate and potent anticancer and anti-metastatic activities

(2017) Shiqun Shao et al.   Nature Biomedical Engineering

Novel antioxidative nanotherapeutics in a rat periodontitis model: Reactive oxygen species scavenging by redox injectable gel suppresses alveolar bone resorption

(2016) Makiko Saita et al.   BIOMATERIALS

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

(2016) Sung Eun Kim et al.   Nature Nanotechnology

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

Silica Nanoparticles Target a Wnt Signal Transducer for Degradation and Impair Embryonic Development in Zebrafish

(2016) Hongyang Yi et al.   Theranostics

Dietary Iron Oxide Nanoparticles Delay Aging and Ameliorate Neurodegeneration inDrosophila

(2015) Yi Zhang et al.   ADVANCED MATERIALS

Programmed synthesis of three-dimensional tissues

(2015) Michael E Todhunter et al.   NATURE METHODS

Ceria Nanoparticles Stabilized by Organic Surface Coatings Activate the Lysosome-Autophagy System and Enhance Autophagic Clearance

(2014) Wensi Song et al.   ACS Nano

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cytosystems dynamics in self-organization of tissue architecture

(2013) Yoshiki Sasai   NATURE