Recent Progress in DNA Hybridization Chain Reaction Strategies for Amplified Biosensing

Tetrahedral Framework Nucleic Acids Loaded with Aptamer AS1411 for siRNA Delivery and Gene Silencing in Malignant Melanoma

(2021) Dexuan Xiao et al.   ACS Applied Materials & Interfaces

Reprogrammable Gel Electrophoresis Detection Assay Using CRISPR-Cas12a and Hybridization Chain Reaction

(2021) Mahera J. Kachwala et al.   ANALYTICAL CHEMISTRY

Organelle‐Specific Photoactivation of DNA Nanosensors for Precise Profiling of Subcellular Enzymatic Activity

(2021) Yulei Shao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hybrid wireframe DNA nanostructures with scaffolded and scaffold‐free modules

(2021) Yan Cui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorometric Paper-Based, Loop-Mediated Isothermal Amplification Devices for Quantitative Point-of-Care Detection of Methicillin-Resistant Staphylococcus aureus (MRSA)

(2021) Ilada Choopara et al.   ACS Sensors

Regulating DNA Self-Assembly Dynamics with Controlled Nucleation

(2021) Shuoxing Jiang et al.   ACS Nano

Hierarchical Hybridization Chain Reaction for Amplified Signal Output and Cascade DNA Logic Circuits

(2021) Wen Yi Lv et al.   ANALYTICAL CHEMISTRY

Stochastic Collision Electrochemistry from Single G-Quadruplex/Hemin: Electrochemical Amplification and MicroRNA Sensing

(2021) Hao Wang et al.   ANALYTICAL CHEMISTRY

A Long and Reversibly Self‐Assembling 1D DNA Nanostructure Built from Triplex and Quadruplex Hybrid Tiles

(2021) Prince Kumar Lat et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetics of Toehold-Mediated DNA Strand Displacement Depend on FeII4L4 Tetrahedron Concentration

(2021) Jinbo Zhu et al.   NANO LETTERS

Porphyrin-Based Covalent Organic Framework Thin Films as Cathodic Materials for “On–Off–On” Photoelectrochemical Sensing of Lead Ions

(2021) Chuanrui Zhao et al.   ACS Applied Materials & Interfaces

Ratiometric Antifouling Electrochemical Biosensors Based on Multifunctional Peptides and MXene Loaded with Au Nanoparticles and Methylene Blue

(2021) Yan Xu et al.   ACS Applied Materials & Interfaces

Plasmonic TiO2@Au NPs//CdS QDs photocurrent-direction switching system for ultrasensitive and selective photoelectrochemical biosensing with cathodic background signal

(2021) Ruiying Yang et al.   ANALYTICA CHIMICA ACTA

Ratiometric Fluorescent DNA Nanostructure for Mitochondrial ATP Imaging in Living Cells Based on Hybridization Chain Reaction

(2021) Lei Luo et al.   ANALYTICAL CHEMISTRY

Electrochemical aptasensor based on multidirectional hybridization chain reaction for detection of tumorous exosomes

(2021) Liangliang Wang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Enhanced electrochemical and SERS signals by self-assembled gold microelectrode arrays: A dual readout platform for multiplex immumoassay of tumor biomarkers

(2021) Xuefang Gu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Proximity hybridization triggered hybridization chain reaction for label-free electrochemical homogeneous aptasensors

(2021) Xianjiu Liao et al.   TALANTA

A highly sensitive aptasensor for the detection of prostate specific antigen based on dumbbell hybridization chain reaction

(2021) Yu Jiang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Near-Atomic Fabrication with Nucleic Acids

(2020) Kai Xia et al.   ACS Nano

Colorimetric Detection of Nucleic Acids through Triplex-Hybridization Chain Reaction and DNA-Controlled Growth of Platinum Nanoparticles on Graphene Oxide

(2020) Weiwei Chen et al.   ANALYTICAL CHEMISTRY

DNA Nanofirecrackers Assembled through Hybridization Chain Reaction for Ultrasensitive SERS Immunoassay of Prostate Specific Antigen

(2020) Jia Ru Wang et al.   ANALYTICAL CHEMISTRY

Elucidation of leak-resistance DNA hybridization chain reaction with universality and extensibility

(2020) Shaofei Li et al.   NUCLEIC ACIDS RESEARCH

DNA Dumbbell and Chameleon Silver Nanoclusters for miRNA Logic Operations

(2020) Yiting Jiang et al.   Research

Controlling the DNA Hybridization Chain Reaction

(2020) C. Adrian Figg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorescence Turn‐On Analysis of Trace Protein Based on Carbon Nanodots and Hybridization Chain Reaction

(2020) Dawei Yang et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

UV–Vis–NIR Full‐Range Responsive Carbon Dots with Large Multiphoton Absorption Cross Sections and Deep‐Red Fluorescence at Nucleoli and In Vivo

(2020) Lei Jiang et al.   Small

Amplified Electrochemical Hydrogen Peroxide Sensing Based on Cu-porphyrin Metal Organic Framework Nanofilm and G-quadruplex-hemin DNAzyme

(2020) Junping Ma et al.   ACS Applied Materials & Interfaces

A Highly Sensitive Electrochemiluminescence Biosensor for Pyrophosphatase Detection Based on Click Chemistry-Triggered Hybridization Chain Reaction in Homogeneous Solution

(2020) Xiaocui Huang et al.   ACS Applied Materials & Interfaces

Quaternary Ammonium Salt-Functionalized Tetraphenylethene Derivative Boosts Electrochemiluminescence for Highly Sensitive Aqueous-Phase Biosensing

(2020) Wenxin Lv et al.   ANALYTICAL CHEMISTRY

One-Step Synthesis of Methylene Blue-Encapsulated Zeolitic Imidazolate Framework for Dual-Signal Fluorescent and Homogeneous Electrochemical Biosensing

(2020) Jiafu Chang et al.   ANALYTICAL CHEMISTRY

Dumbbell Hybridization Chain Reaction Based Electrochemical Biosensor for Ultrasensitive Detection of Exosomal miRNA

(2020) Peng Miao et al.   ANALYTICAL CHEMISTRY

Aptamer-quantum dots and teicoplanin-gold nanoparticles constructed FRET sensor for sensitive detection of Staphylococcus aureus

(2020) Xiaoqi Tao et al.   CHINESE CHEMICAL LETTERS

Sensitive, enzyme-free and label-free electrochemical sensor for K-ras G12D point mutation detection based on double cascade amplification reaction

(2020) Xiaomei Zhou et al.   JOURNAL OF ELECTROANALYTICAL CHEMISTRY

Two-Dimensional Hybridization Chain Reaction Strategy for Highly Sensitive Analysis of Intracellular mRNA

(2020) Peng Miao et al.   ANALYTICAL CHEMISTRY

Ultrasensitive colorimetric biosensor for BRCA1 mutation based on multiple signal amplification strategy

(2020) Yunfei Bai et al.   BIOSENSORS & BIOELECTRONICS

Site-Selective RNA Functionalization via DNA-Induced Structure

(2020) Lu Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Three-Dimensional DNA Nanomachine Combined with Toehold-Mediated Strand Displacement Reaction for Sensitive Electrochemical Detection of MiRNA

(2020) Hanwen Lu et al.   LANGMUIR

Click chemistry reaction-triggered DNA walker amplification coupled with hyperbranched DNA nanostructure for versatile fluorescence detection and drug delivery to cancer cells

(2020) Chunli Li et al.   Microchimica Acta

Cross-Inhibitor: a time-sensitive molecular circuit based on DNA strand displacement

(2020) Chanjuan Liu et al.   NUCLEIC ACIDS RESEARCH

Multiplexed detection of tumor biomarkers utilizing immunohybridization Chain reaction integrated photonic barcodes

(2020) Dagan Zhang et al.   SENSORS AND ACTUATORS B-CHEMICAL

The Recent Development of Hybridization Chain Reaction Strategies in Biosensors

(2020) Chuyan Zhang et al.   ACS Sensors

Precise Capture and Direct Quantification of Tumor Exosomes via a Highly Efficient Dual-Aptamer Recognition-Assisted Ratiometric Immobilization-Free Electrochemical Strategy

(2020) Limin Yang et al.   ANALYTICAL CHEMISTRY

5-Hydroxymethylcytosine Glucosylation-Triggered Helicase-Dependent Amplification-Based Fluorescent Biosensor for Sensitive Detection of β-Glucosyltransferase with Zero Background Signal

(2020) Meng Liu et al.   ANALYTICAL CHEMISTRY

Development of a simple, sensitive and selective colorimetric aptasensor for the detection of cancer-derived exosomes

(2020) Lizhou Xu et al.   BIOSENSORS & BIOELECTRONICS

Synthesis of highly ordered AgNPs-coated silica photonic crystal beads for sensitive and reproducible 3D SERS substrates

(2020) Juan Li et al.   CHINESE CHEMICAL LETTERS

Fuel-Driven Transient DNA Strand Displacement Circuitry with Self-Resetting Function

(2020) Jie Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Protecting Biomimetic Nanozyme for Selective and Synergistic Clearance of Peripheral Amyloid-β in an Alzheimer’s Disease Model

(2020) Mengmeng Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Triple ionic–electronic conducting oxides for next-generation electrochemical devices

(2020) Meagan Papac et al.   NATURE MATERIALS

Novel multiple strand displacement reaction coupled hybridization chain reaction for label-free and ultrasensitive electrochemical Type b3a2 biosensing

(2020) Changrui Feng et al.   SENSORS AND ACTUATORS B-CHEMICAL

Application of a microfluidic paper-based bioimmunosensor with laser-induced fluorescence detection in the determination of alpha-fetoprotein from serum of hepatopaths

(2020) Wei Wang et al.   TALANTA

Enzyme-free electrochemical biosensor based on amplification of proximity-dependent surface hybridization chain reaction for ultrasensitive mRNA detection

(2020) Yu-Hong Cheng et al.   TALANTA

Autocatalytic MNAzyme-integrated surface plasmon resonance biosensor for simultaneous detection of bacteria from nosocomial bloodstream infection specimens

(2020) Han Xia et al.   SENSORS AND ACTUATORS B-CHEMICAL

Electrode immobilization-free and sensitive electrochemical sensing of thrombin via magnetic nanoparticle-decorated DNA polymers

(2020) Feng Qiu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Highly sensitive detection of cancer cells via split aptamer mediated proximity-induced hybridization chain reaction

(2020) Lie Li et al.   TALANTA

CRISPR-Cas12a-driven MXene-PEDOT:PSS piezoresistive wireless biosensor

(2020) Ruijin Zeng et al.   Nano Energy

Cascade Toehold-Mediated Strand Displacement Reaction for Ultrasensitive Detection of Exosomal MicroRNA

(2020) Peng Miao et al.   CCS Chemistry

An electrochemical biosensor for DNA methylation detection through hybridization chain amplified reaction coupled with a tetrahedral DNA nanostructure

(2019) Xi Chen et al.   ACS Applied Materials & Interfaces

Metastable Dumbbell Probe-Based Hybridization Chain Reaction for Sensitive and Accurate Imaging of Intracellular-Specific MicroRNAs In Situ in Living Cells

(2019) Jun Chen et al.   ANALYTICAL CHEMISTRY

Label-Free and Enzyme-Free Colorimetric Detection of Pb2+ Based on RNA Cleavage and Annealing-Accelerated Hybridization Chain Reaction

(2019) Zhijun Huang et al.   ANALYTICAL CHEMISTRY

Concatenated Catalytic Hairpin Assembly/Hyperbranched Hybridization Chain Reaction Based Enzyme-Free Signal Amplification for the Sensitive Photoelectrochemical Detection of Human Telomerase RNA

(2019) Yanxin Chu et al.   ANALYTICAL CHEMISTRY

Dandelion-like CuO microspheres decorated with Au nanoparticle modified biosensor for Hg2+ detection using a T-Hg2+-T triggered hybridization chain reaction amplification strategy

(2019) Yujie Yu et al.   BIOSENSORS & BIOELECTRONICS

Label-free and amplified electrogenerated chemiluminescence biosensing for the detection of thymine DNA glycosylase activity using DNA-functionalized gold nanoparticles triggered hybridization chain reaction

(2019) Wanqiao Bai et al.   ANALYTICA CHIMICA ACTA

Mesoporous Silica Containers and Programmed Catalytic Hairpin Assembly/Hybridization Chain Reaction Based Electrochemical Sensing Platform for miRNA Ultrasensitive Detection with Low Background

(2019) Hong Cheng et al.   ANALYTICAL CHEMISTRY

Fabrication of Polymeric Ferrocene Nanoparticles for Electrochemical Aptasensing of Protein with Target-Catalyzed Hairpin Assembly

(2019) Hua Chai et al.   ANALYTICAL CHEMISTRY

Ultrasensitive Electrochemiluminescence Detection of MicroRNA via One-Step Introduction of a Target-Triggered Branched Hybridization Chain Reaction Circuit

(2019) Yang Li et al.   ANALYTICAL CHEMISTRY

Construction of an Autonomous Nonlinear Hybridization Chain Reaction for Extracellular Vesicles-Associated MicroRNAs Discrimination

(2019) Qiong Wu et al.   ANALYTICAL CHEMISTRY

Near-infrared Light-Initiated Hybridization Chain Reaction for Spatially- and Temporally-Resolved Signal Amplification

(2019) Hongqian Chu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A ratiometric electrochemical assay for human 8-oxoguanine DNA glycosylase amplified by hybridization chain reaction

(2019) Dawei Yang et al.   ELECTROCHEMISTRY COMMUNICATIONS

Sensitive determination of the human epidermal growth factor receptor 2 (HER2) by immuno-polymerase chain reaction with inductively coupled plasma-mass spectrometry detection

(2019) A. Fernández Asensio et al.   ANALYTICA CHIMICA ACTA

Fine-Tuning Ho-Based Red-Upconversion Luminescence by Altering NaHoF4 Core Size and NaYbF4 Shell Thickness

(2019) Ye Kuang et al.   CHEMISTRY OF MATERIALS

Triple-Input Molecular AND Logic Gates for Sensitive Detection of Multiple miRNAs

(2019) Xiaoyi Ma et al.   ACS Applied Materials & Interfaces

Biomedical Applications of DNA‐Based Hydrogels

(2019) Jasmina Gačanin et al.   ADVANCED FUNCTIONAL MATERIALS

Electrochemical detection of T4 polynucleotide kinase based on target-assisted ligation reaction coupled with silver nanoparticles

(2019) Yu Jiang et al.   ANALYTICA CHIMICA ACTA

Chameleon silver nanoclusters for ratiometric sensing of miRNA

(2019) Yiting Jiang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Programming Drug Delivery Kinetics for Active Burst Release with DNA Toehold Switches

(2019) Mingshu Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Programming DNA origami patterning with non-canonical DNA-based metallization reactions

(2019) Sisi Jia et al.   Nature Communications

Branched Hybridization Chain Reaction Circuit for Ultrasensitive Localizable Imaging of mRNA in Living Cells

(2018) Lan Liu et al.   ANALYTICAL CHEMISTRY

Tetrahedral DNA probe coupling with hybridization chain reaction for competitive thrombin aptasensor

(2018) Ying-Xu Chen et al.   BIOSENSORS & BIOELECTRONICS

Nanoparticles for super-resolution microscopy and single-molecule tracking

(2018) Dayong Jin et al.   NATURE METHODS

Protein scaffolded DNA tetrads enable efficient delivery and ultrasensitive imaging of miRNA through crosslinking hybridization chain reaction

(2018) Du-Juan Huang et al.   Chemical Science

Construction of an autonomously concatenated hybridization chain reaction for signal amplification and intracellular imaging

(2018) Jie Wei et al.   Chemical Science

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

(2018) Marcel Naumann et al.   Nature Communications

Chemical and Biological Sensing Using Hybridization Chain Reaction

(2018) Erik E. Augspurger et al.   ACS Sensors

Electrochemical Detection of miRNA Combining T7 Exonuclease-Assisted Cascade Signal Amplification and DNA-Templated Copper Nanoparticles

(2018) Peng Miao et al.   ANALYTICAL CHEMISTRY

Electrochemical detection of arsenic contamination based on hybridization chain reaction and RecJf exonuclease-mediated amplification

(2018) Haidong Gu et al.   CHEMICAL ENGINEERING JOURNAL

Combination of Magnetic-Beads-Based Multiple Metal Nanoparticles Labeling with Hybridization Chain Reaction Amplification for Simultaneous Detection of Multiple Cancer Cells with Inductively Coupled Plasma Mass Spectrometry

(2018) Ye He et al.   ANALYTICAL CHEMISTRY

Amplified Visualization of Protein-Specific Glycosylation in Zebrafish via Proximity-Induced Hybridization Chain Reaction

(2018) Jingying Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A label-free electrochemical biosensor for microRNAs detection based on DNA nanomaterial by coupling with Y-shaped DNA structure and non-linear hybridization chain reaction

(2018) Lin Zhou et al.   BIOSENSORS & BIOELECTRONICS

DNA Hydrogel with Aptamer-Toehold-Based Recognition, Cloaking, and Decloaking of Circulating Tumor Cells for Live Cell Analysis

(2017) Ping Song et al.   NANO LETTERS

Gold Nanoparticles-Based DNA Logic Gate for miRNA Inputs Analysis Coupling Strand Displacement Reaction and Hybridization Chain Reaction

(2017) Xiaoyi Ma et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Hybridization chain reaction directed DNA superstructures assembly for biosensing applications

(2017) Dawei Yang et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

A dual-amplification system for colorimetric DNA detection based on the assembly of biomolecules

(2017) Chaohui Chen et al.   CHINESE CHEMICAL LETTERS

Ultra-Sensitive Colorimetric Assay System Based on the Hybridization Chain Reaction-Triggered Enzyme Cascade Amplification

(2016) Shasha Lu et al.   ACS Applied Materials & Interfaces

Ultrasensitive Multiplexed Immunoassay for Tumor Biomarkers Based on DNA Hybridization Chain Reaction Amplifying Signal

(2016) Jinjin Guo et al.   ACS Applied Materials & Interfaces

Near-Infrared Ag2S Quantum Dots-Based DNA Logic Gate Platform for miRNA Diagnostics

(2016) Peng Miao et al.   ANALYTICAL CHEMISTRY

Fluorescence resonance energy transfer-based hybridization chain reaction for in situ visualization of tumor-related mRNA

(2016) Jin Huang et al.   Chemical Science

Three-dimensional controlled growth of monodisperse sub-50 nm heterogeneous nanocrystals

(2016) Deming Liu et al.   Nature Communications

Label-free fluorescence dual-amplified detection of adenosine based on exonuclease III-assisted DNA cycling and hybridization chain reaction

(2015) Jiewei Sun et al.   BIOSENSORS & BIOELECTRONICS

MicroRNA detection based on analyte triggered nanoparticle localization on a tetrahedral DNA modified electrode followed by hybridization chain reaction dual amplification

(2015) Peng Miao et al.   CHEMICAL COMMUNICATIONS

Proximity-dependent initiation of hybridization chain reaction

(2015) Björn Koos et al.   Nature Communications

Melamine Functionalized Silver Nanoparticles as the Probe for Electrochemical Sensing of Clenbuterol

(2014) Peng Miao et al.   ACS Applied Materials & Interfaces

Electrochemical Switching with 3D DNA Tetrahedral Nanostructures Self-Assembled at Gold Electrodes

(2014) Alireza Abi et al.   ACS Applied Materials & Interfaces

Triggering Hairpin-Free Chain-Branching Growth of Fluorescent DNA Dendrimers for Nonlinear Hybridization Chain Reaction

(2014) Feng Xuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hybridization chain reaction-based branched rolling circle amplification for chemiluminescence detection of DNA methylation

(2013) Sai Bi et al.   CHEMICAL COMMUNICATIONS

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Attomolar Ultrasensitive MicroRNA Detection by DNA-Scaffolded Silver-Nanocluster Probe Based on Isothermal Amplification

(2012) Yu-Qiang Liu et al.   ANALYTICAL CHEMISTRY

Protein Detection Based on Small Molecule-Linked DNA

(2012) Ya Cao et al.   ANALYTICAL CHEMISTRY

Controllable Deposition of a Platinum Nanoparticle Ensemble on a Polyaniline/Graphene Hybrid as a Novel Electrode Material for Electrochemical Sensing

(2012) Jian-Ding Qiu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Probing Spatial Organization of DNA Strands Using Enzyme-Free Hairpin Assembly Circuits

(2012) Bingling Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An electrochemical alkaline phosphatase biosensor fabricated with two DNA probes coupled with λ exonuclease

(2011) Peng Miao et al.   BIOSENSORS & BIOELECTRONICS

Amplified Analysis of DNA by the Autonomous Assembly of Polymers Consisting of DNAzyme Wires

(2011) Fuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Size-Dependent Electrochemical Oxidation of Silver Nanoparticles

(2009) Olga S. Ivanova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY