Click CAR-T cell engineering for robustly boosting cell immunotherapy in blood and subcutaneous xenograft tumor

Hyperspectral cell sociology reveals spatial tumor-immune cell interactions associated with lung cancer recurrence

(2019) Katey S. S. Enfield et al.   Journal for ImmunoTherapy of Cancer

CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

(2019) Mohamad Hamieh et al.   NATURE

Enhancing tumor T cell infiltration to enable cancer immunotherapy

(2019) Jin Zhang et al.   Immunotherapy

Glycometabolic Bioorthogonal Chemistry‐Guided Viral Transduction for Robust Human T Cell Engineering

(2019) Hong Pan et al.   ADVANCED FUNCTIONAL MATERIALS

T Cell Membrane Mimicking Nanoparticles with Bioorthogonal Targeting and Immune Recognition for Enhanced Photothermal Therapy

(2019) Yutong Han et al.   Advanced Science

Endogenous T cells prevent tumor immune escape following adoptive T cell therapy

(2019) Scott R. Walsh et al.   JOURNAL OF CLINICAL INVESTIGATION

An intra-tumoral niche maintains and differentiates stem-like CD8 T cells

(2019) Caroline S. Jansen et al.   NATURE

IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor

(2018) Keishi Adachi et al.   NATURE BIOTECHNOLOGY

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

CAR T cell immunotherapy for human cancer

(2018) Carl H. June et al.   SCIENCE

CAR-T cells: the long and winding road to solid tumors

(2018) Maria Michela D’Aloia et al.   Cell Death & Disease

Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection

(2018) Daniel Kummer et al.   Cells

Dissecting complicated viral spreading of enterovirus 71 using in situ bioorthogonal fluorescent labeling

(2018) Hong Pan et al.   BIOMATERIALS

Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia

(2018) Elena J. Orlando et al.   NATURE MEDICINE

Tumor Antigen Escape from CAR T-cell Therapy

(2018) Robbie G. Majzner et al.   Cancer Discovery

Bio-Orthogonal T Cell Targeting Strategy for Robustly Enhancing Cytotoxicity against Tumor Cells

(2018) Wenjun Li et al.   Small

Cyclopropenones for Metabolic Targeting and Sequential Bioorthogonal Labeling

(2017) R. David Row et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy

(2017) Terry J Fry et al.   NATURE MEDICINE

In Situ Bioorthogonal Metabolic Labeling for Fluorescence Imaging of Virus Infection In Vivo

(2017) Hong Pan et al.   Small

Increasing Tumor-Infiltrating T Cells through Inhibition of CXCL12 with NOX-A12 Synergizes with PD-1 Blockade

(2017) Dirk Zboralski et al.   Cancer Immunology Research

Global Manufacturing of CAR T Cell Therapy

(2017) Bruce L. Levine et al.   Molecular Therapy-Methods & Clinical Development

Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting

(2016) Clare Y. Slaney et al.   CLINICAL CANCER RESEARCH

Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy

(2016) Hanren Dai et al.   JNCI-Journal of the National Cancer Institute

Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies

(2016) David T. Rodgers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy

(2016) Hanren Dai et al.   JNCI-Journal of the National Cancer Institute

T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells

(2016) E. Zah et al.   Cancer Immunology Research

Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry

(2015) Paresh Agarwal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genetically modified T cells in cancer therapy: opportunities and challenges

(2015) M. Sharpe et al.   Disease Models & Mechanisms

Bioorthogonal Click Chemistry-Based Synthetic Cell Glue

(2015) Heebeom Koo et al.   Small

Noninvasive Visualization of Respiratory Viral Infection Using Bioorthogonal Conjugated Near-Infrared-Emitting Quantum Dots

(2014) Hong Pan et al.   ACS Nano

Enhancement of T cell recruitment and infiltration into tumours

(2014) C. Oelkrug et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immune Escape Mechanisms as a Guide for Cancer Immunotherapy

(2014) G. L. Beatty et al.   CLINICAL CANCER RESEARCH

Anti-tumor activity of obinutuzumab and rituximab in a follicular lymphoma 3D model

(2013) E Decaup et al.   Blood Cancer Journal

A Non-Fluorinated Monobenzocyclooctyne for Rapid Copper-Free Click Reactions

(2011) Balázs R. Varga et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE