Endogenous T cells prevent tumor immune escape following adoptive T cell therapy

Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity

(2018) Scott R. Walsh et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutic T cell engineering

(2017) Michel Sadelain et al.   NATURE

Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

(2016) Willy Hugo et al.   CELL

Mutational Landscape and Sensitivity to Immune Checkpoint Blockers

(2016) R. M. Chabanon et al.   CLINICAL CANCER RESEARCH

T-Cell Therapy Using Interleukin-21–Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression

(2016) Aude G. Chapuis et al.   JOURNAL OF CLINICAL ONCOLOGY

Privileged Antigen Presentation in Splenic B Cell Follicles Maximizes T Cell Responses in Prime-Boost Vaccination

(2016) Byram W. Bridle et al.   JOURNAL OF IMMUNOLOGY

Safety concerns blight promising cancer therapy

(2016) Heidi Ledford   NATURE

Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells

(2016) Arnold Hayer et al.   NATURE CELL BIOLOGY

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

(2016) Eric Tran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

(2016) N. McGranahan et al.   SCIENCE

Role of memory T cell subsets for adoptive immunotherapy

(2016) Dirk H. Busch et al.   SEMINARS IN IMMUNOLOGY

Towards a commercial process for the manufacture of genetically modified T cells for therapy

(2015) A D Kaiser et al.   CANCER GENE THERAPY

The Evolution of T-cell Therapies for Solid Malignancies

(2015) K. Fousek et al.   CLINICAL CANCER RESEARCH

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

T-cell-based Immunotherapy: Adoptive Cell Transfer and Checkpoint Inhibition

(2015) R. Houot et al.   Cancer Immunology Research

An optimized peptide vaccine strategy capable of inducing multivalent CD8+T cell responses with potent antitumor effects

(2015) Hyun-Il Cho et al.   OncoImmunology

A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1-Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response

(2014) P. F. Robbins et al.   CLINICAL CANCER RESEARCH

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

(2014) Fei Duan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

(2014) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

(2014) E. Tran et al.   SCIENCE

Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells

(2014) Seth M Pollack et al.   Journal for ImmunoTherapy of Cancer

Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy

(2013) Joseph G. Crompton et al.   IMMUNOLOGICAL REVIEWS

Sustained Complete Responses in Patients With Lymphoma Receiving Autologous Cytotoxic T Lymphocytes Targeting Epstein-Barr Virus Latent Membrane Proteins

(2013) Catherine M. Bollard et al.   JOURNAL OF CLINICAL ONCOLOGY

Maraba Virus as a Potent Oncolytic Vaccine Vector

(2013) Jonathan G Pol et al.   MOLECULAR THERAPY

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Safety Studies on Intravenous Administration of Oncolytic Recombinant Vesicular Stomatitis Virus in Purpose-Bred Beagle Dogs

(2013) Amy K. LeBlanc et al.   Human Gene Therapy Clinical Development

Adoptive T-Cell Therapy Using Autologous Tumor-Infiltrating Lymphocytes for Metastatic Melanoma

(2012) Richard Wu et al.   CANCER JOURNAL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

CAR–T cells and solid tumors: tuning T cells to challenge an inveterate foe

(2012) David E. Gilham et al.   TRENDS IN MOLECULAR MEDICINE

Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma

(2011) C. U. Louis et al.   BLOOD

Antigen Spreading Contributes to MAGE Vaccination-Induced Regression of Melanoma Metastases

(2011) Véronique Corbière et al.   CANCER RESEARCH

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

(2011) Caroline J. Breitbach et al.   NATURE

Potentiating Cancer Immunotherapy Using an Oncolytic Virus

(2010) Byram W Bridle et al.   MOLECULAR THERAPY

Local and Distant Immunity Induced by Intralesional Vaccination with an Oncolytic Herpes Virus Encoding GM-CSF in Patients with Stage IIIc and IV Melanoma

(2009) Howard L. Kaufman et al.   ANNALS OF SURGICAL ONCOLOGY

Increased Intensity Lymphodepletion Enhances Tumor Treatment Efficacy of Adoptively Transferred Tumor-specific T Cells

(2009) Claudia Wrzesinski et al.   JOURNAL OF IMMUNOTHERAPY