A Non-Fluorinated Monobenzocyclooctyne for Rapid Copper-Free Click Reactions

Biomedical Applications of Tetrazine Cycloadditions

(2011) Neal K. Devaraj et al.   ACCOUNTS OF CHEMICAL RESEARCH

Strain-Promoted Alkyne-Azide Cycloadditions (SPAAC) Reveal New Features of Glycoconjugate Biosynthesis

(2011) Ngalle Eric Mbua et al.   CHEMBIOCHEM

Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine–trans-Cyclooctene Ligation

(2011) Michael T. Taylor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical strategies for tagging and imaging the proteome

(2011) Kimberly E. Beatty   Molecular BioSystems

A Metabolic Alkene Reporter for Spatiotemporally Controlled Imaging of Newly Synthesized Proteins in Mammalian Cells

(2010) Wenjiao Song et al.   ACS Chemical Biology

Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells

(2010) Jan Dommerholt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Labeling Live Cells by Copper-Catalyzed Alkyne−Azide Click Chemistry

(2010) Vu Hong et al.   BIOCONJUGATE CHEMISTRY

Azide: A Unique Dipole for Metal-Free Bioorthogonal Ligations

(2010) Marjoke F. Debets et al.   CHEMBIOCHEM

Bioorthogonal chemistry: recent progress and future directions

(2010) Reyna K. V. Lim et al.   CHEMICAL COMMUNICATIONS

Cu-free click cycloaddition reactions in chemical biology

(2010) John C. Jewett et al.   CHEMICAL SOCIETY REVIEWS

New Far-red and Near-infrared Fluorescent Probes with Large Stokes Shifts for Dual Covalent Labeling of DNA

(2010) Thomas Ehrenschwender et al.   Chemistry-An Asian Journal

Difluorobenzocyclooctyne: Synthesis, Reactivity, and Stabilization by β-Cyclodextrin

(2010) Ellen M. Sletten et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocompatible Copper(I) Catalysts for in Vivo Imaging of Glycans

(2010) David Soriano del Amo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid Cu-Free Click Chemistry with Readily Synthesized Biarylazacyclooctynones

(2010) John C. Jewett et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Free Sequential [3 + 2]-Dipolar Cycloadditions using Cyclooctynes and 1,3-Dipoles of Different Reactivity

(2010) Brian C. Sanders et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A bioorthogonal chemistry strategy for probing protein lipidation in live cells

(2010) Wenjiao Song et al.   Molecular BioSystems

Copper-free click chemistry in living animals

(2010) P. V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Click Chemistry beyond Metal-Catalyzed Cycloaddition

(2009) C. Remzi Becer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Probing the Activity of Matrix Metalloproteinase II with a Sequentially Click-Labeled Silica Nanoparticle FRET Probe

(2009) Daniela E. Achatz et al.   CHEMBIOCHEM

Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition

(2009) Marjoke F. Debets et al.   CHEMICAL COMMUNICATIONS

Cyclooctyne-based reagents for uncatalyzed click chemistry: A computational survey

(2009) Kimberly Chenoweth et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Clickable fluorophores for biological labeling—with or without copper

(2009) Péter Kele et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo

(2009) I. C. Tanrikulu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual Labeling of Biomolecules by Using Click Chemistry: A Sequential Approach

(2008) Péter Kele et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

(2008) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition States of Strain-Promoted Metal-Free Click Chemistry:  1,3-Dipolar Cycloadditions of Phenyl Azide and Cyclooctynes

(2008) Daniel H. Ess et al.   ORGANIC LETTERS