Machine Learning Establishes Single-Cell Calcium Dynamics as an Early Indicator of Antibiotic Response

A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence

(2020) Takushi Shimomura et al.   eLife

Surfactant-enhanced DNA accessibility to nuclease accelerates phenotypic β-lactam antibiotic susceptibility testing of Neisseria gonorrhoeae

(2020) Emily S. Savela et al.   PLOS BIOLOGY

Temporal encoding of bacterial identity and traits in growth dynamics

(2020) Carolyn Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane voltage dysregulation driven by metabolic dysfunction underlies bactericidal activity of aminoglycosides

(2020) Giancarlo Noe Bruni et al.   eLife

Automated, Cost-Effective Optical System for Accelerated Antimicrobial Susceptibility Testing (AST) Using Deep Learning

(2020) Calvin Brown et al.   ACS Photonics

Evidence of Calcium Signaling and Modulation of the LmrS Multidrug Resistant Efflux Pump Activity by Ca2 + Ions in S. aureus

(2020) Amy R. Nava et al.   Frontiers in Microbiology

Magnesium Flux Modulates Ribosomes to Increase Bacterial Survival

(2019) Dong-yeon D. Lee et al.   CELL

Definitions and guidelines for research on antibiotic persistence

(2019) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

Statistics of correlated percolation in a bacterial community

(2019) Xiaoling Zhai et al.   PLoS Computational Biology

Phenotypic Antimicrobial Susceptibility Testing with Deep Learning Video Microscopy

(2018) Hui Yu et al.   ANALYTICAL CHEMISTRY

Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens

(2018) Bradley M. Hover et al.   Nature Microbiology

Glutamate triggers long-distance, calcium-based plant defense signaling

(2018) Masatsugu Toyota et al.   SCIENCE

Signal Percolation within a Bacterial Community

(2018) Joseph W. Larkin et al.   Cell Systems

Use of the Accelerate Pheno System for Identification and Antimicrobial Susceptibility Testing of Pathogens in Positive Blood Cultures and Impact on Time to Results and Workflow

(2017) Angella Charnot-Katsikas et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Voltage-gated calcium flux mediatesEscherichia colimechanosensation

(2017) Giancarlo N. Bruni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

(2017) Özden Baltekin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Efflux Pump Inhibitors on Colistin Resistance in Multidrug-Resistant Gram-Negative Bacteria

(2016) Wentao Ni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes

(2016) Mark-Anthony Bray et al.   Nature Protocols

Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes

(2016) Anna Raffaello et al.   TRENDS IN BIOCHEMICAL SCIENCES

Calcium binding proteins and calcium signaling in prokaryotes

(2015) Delfina C. Domínguez et al.   CELL CALCIUM

Ion channels enable electrical communication in bacterial communities

(2015) Arthur Prindle et al.   NATURE

The oncogene c-Jun impedes somatic cell reprogramming

(2015) Jing Liu et al.   NATURE CELL BIOLOGY

Autophagy Induced by Calcium Phosphate Precipitates Targets Damaged Endosomes

(2014) Xi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium homeostasis in Pseudomonas aeruginosa requires multiple transporters and modulates swarming motility

(2013) Manita Guragain et al.   CELL CALCIUM

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Fe-S Cluster Biosynthesis Controls Uptake of Aminoglycosides in a ROS-Less Death Pathway

(2013) B. Ezraty et al.   SCIENCE

Cation Concentration Variability of Four Distinct Mueller-Hinton Agar Brands Influences Polymyxin B Susceptibility Results

(2012) R. Girardello et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics

(2012) J. J. Foti et al.   SCIENCE

Electrical Spiking in Escherichia coli Probed with a Fluorescent Voltage-Indicating Protein

(2011) Joel M. Kralj et al.   SCIENCE

The βγ-Crystallin Superfamily Contains a Universal Motif for Binding Calcium,

(2009) Penmatsa Aravind et al.   BIOCHEMISTRY

ATP Regulates Calcium Efflux and Growth in E. coli

(2009) Riffat Naseem et al.   JOURNAL OF MOLECULAR BIOLOGY

pH and monovalent cations regulate cytosolic free Ca2+ in E. coli

(2008) Riffat Naseem et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Calcium efflux is essential for bacterial survival in the eukaryotic host

(2008) Jason W. Rosch et al.   MOLECULAR MICROBIOLOGY