Icaritin Provides Neuroprotection in Parkinson’s Disease by Attenuating Neuroinflammation, Oxidative Stress, and Energy Deficiency

Protective effect of the sphingosine-1 phosphate receptor agonist siponimod on disrupted blood brain barrier function

(2021) Simona Federica Spampinato et al.   BIOCHEMICAL PHARMACOLOGY

Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles

(2020) Slava Rom et al.   Scientific Reports

Icaritin activates Nrf2/Keap1 signaling to protect neuronal cells from oxidative stress

(2020) Yuyu Xu et al.   Chemical Biology & Drug Design

Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease

(2019) Xiaojuan Han et al.   Autophagy

In vivo GluCEST MRI: Reproducibility, background contribution and source of glutamate changes in the MPTP model of Parkinson’s disease

(2018) Puneet Bagga et al.   Scientific Reports

figHigh Spatial Resolution MALDI‐MS Imaging in the Study of Membranous Nephropathy

(2018) Andrew Smith et al.   Proteomics Clinical Applications

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

(2017) Lena F. Burbulla et al.   SCIENCE

Inflammasome Priming in Sterile Inflammatory Disease

(2017) Meghana N. Patel et al.   TRENDS IN MOLECULAR MEDICINE

Does Vitamin C Influence Neurodegenerative Diseases and Psychiatric Disorders?

(2017) et al.   Nutrients

Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson’s Disease through NF-κB/pAKT Signaling Pathways

(2017) Sachchida N. Rai et al.   Frontiers in Aging Neuroscience

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

Mass Spectrometry Imaging of Kidney Tissue Sections of Rat Subjected to Unilateral Ureteral Obstruction

(2017) Huihui Liu et al.   Scientific Reports

Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease

(2016) J. A. Bayliss et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson’s disease

(2016) Yan Zhou et al.   Molecular Neurodegeneration

Icariin Metabolism by Human Intestinal Microflora

(2016) Hailong Wu et al.   MOLECULES

Icaritin Attenuates Myocardial Ischemia and Reperfusion Injury Via Anti-Inflammatory and Anti-Oxidative Stress Effects in Rats

(2015) Wei Zhang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

Neuroprotective Effects of Icariin on Brain Metabolism, Mitochondrial Functions, and Cognition in Triple-Transgenic Alzheimer's Disease Mice

(2015) Yi-Jing Chen et al.   CNS Neuroscience & Therapeutics

SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth

(2015) H. Yang et al.   EMBO JOURNAL

Drivers of age-related inflammation and strategies for healthspan extension

(2015) Emily L. Goldberg et al.   IMMUNOLOGICAL REVIEWS

1,5-Diaminonaphthalene Hydrochloride Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Small Molecules in Tissues Following Focal Cerebral Ischemia

(2014) Huihui Liu et al.   ANALYTICAL CHEMISTRY

Pattern recognition receptors and central nervous system repair

(2014) Kristina A. Kigerl et al.   EXPERIMENTAL NEUROLOGY

The ongoing pursuit of neuroprotective therapies in Parkinson disease

(2014) Dilan Athauda et al.   Nature Reviews Neurology

Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging

(2013) Yun-Hee Youm et al.   Cell Metabolism

Icaritin exhibits anti-inflammatory effects in the mouse peritoneal macrophages and peritonitis model

(2013) Xinqiang Lai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mitochondrial dysfunction and oxidative stress in Parkinson's disease

(2013) Sudhakar Raja Subramaniam et al.   PROGRESS IN NEUROBIOLOGY

Taurine and central nervous system disorders

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Neuroprotection of hydroxysafflor yellow A in the transient focal ischemia: Inhibition of protein oxidation/nitration, 12/15-lipoxygenase and blood–brain barrier disruption

(2012) Li Sun et al.   BRAIN RESEARCH

Animal models of Parkinson’s disease

(2012) Fabio Blandini et al.   FEBS Journal

Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies

(2012) Hyun Ku Kang et al.   FOOD AND CHEMICAL TOXICOLOGY

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Genetic Animal Models of Parkinson's Disease

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AMP-activated protein kinase is activated in Parkinson’s disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

(2009) Jae-Sun Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease

(2009) Sung Tae Kim et al.   BRAIN RESEARCH

Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease

(2009) Hansruedi Büeler   EXPERIMENTAL NEUROLOGY

A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson's Disease

(2009) C. Warren Olanow et al.   NEW ENGLAND JOURNAL OF MEDICINE