Vaccination by Two DerG LEAPS Conjugates Incorporating Distinct Proteoglycan (PG, Aggrecan) Epitopes Provides Therapy by Different Immune Mechanisms in a Mouse Model of Rheumatoid Arthritis

Risk for development of inflammatory bowel disease under inhibition of interleukin 17: A systematic review and meta-analysis

(2020) Johan Burisch et al.   PLoS One

Peptide-Based Vaccination Therapy for Rheumatic Diseases

(2020) Bin Wang et al.   Journal of Immunology Research

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*

(2020) Nathalie Percie du Sert et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

JAK-Inhibitors for the Treatment of Rheumatoid Arthritis: A Focus on the Present and an Outlook on the Future

(2020) Jacopo Angelini et al.   Biomolecules

Blocking IL-17: A Promising Strategy in the Treatment of Systemic Rheumatic Diseases

(2020) Carlos Rafael-Vidal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting Interleukin-6 Signaling in Clinic

(2019) Sujin Kang et al.   IMMUNITY

Ginsenoside Rh2 Ameliorates Atopic Dermatitis in NC/Nga Mice by Suppressing NF-kappaB-Mediated Thymic Stromal Lymphopoietin Expression and T Helper Type 2 Differentiation

(2019) Eunsu Ko et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Humoral Epitope Spreading in Autoimmune Bullous Diseases

(2018) Dario Didona et al.   Frontiers in Immunology

OUP accepted manuscript

(2018)   RHEUMATOLOGY

The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases

(2018) Maria Grazia Roncarolo et al.   IMMUNITY

Pathogenic Role of Immune Cells in Rheumatoid Arthritis: Implications in Clinical Treatment and Biomarker Development

(2018) Hooi-Yeen Yap et al.   Cells

An epitope-specific DerG-PG70 LEAPS vaccine modulates T cell responses and suppresses arthritis progression in two related murine models of rheumatoid arthritis

(2017) Katalin Mikecz et al.   VACCINE

Interleukin (IL-6) Immunotherapy

(2017) Toshio Tanaka et al.   Cold Spring Harbor Perspectives in Biology

Profile of sarilumab and its potential in the treatment of rheumatoid arthritis

(2017) Maria Gabriella Raimondo et al.   Drug Design Development and Therapy

Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis

(2016) Adrienn Markovics et al.   PLoS One

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production

(2015) Ia Khmaladze et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Rheumatoid arthritis vaccine therapies: perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritis

(2015) Kenneth S Rosenthal et al.   Expert Review of Vaccines

Of mice and men: how animal models advance our understanding of T-cell function in RA

(2014) Tamás Kobezda et al.   Nature Reviews Rheumatology

Suppression of Proteoglycan-Induced Autoimmune Arthritis by Myeloid-Derived Suppressor Cells Generated In Vitro from Murine Bone Marrow

(2014) Júlia Kurkó et al.   PLoS One

The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis

(2013) Petra Misják et al.   IMMUNOLOGY LETTERS

Antigen-activated dendritic cells ameliorate influenza A infections

(2013) Kobporn Boonnak et al.   JOURNAL OF CLINICAL INVESTIGATION

Location of CD4+ T Cell Priming Regulates the Differentiation of Th1 and Th17 Cells and Their Contribution to Arthritis

(2013) R. Rodeghero et al.   JOURNAL OF IMMUNOLOGY

Porphyromonas gingivalis Facilitates the Development and Progression of Destructive Arthritis through Its Unique Bacterial Peptidylarginine Deiminase (PAD)

(2013) Katarzyna J. Maresz et al.   PLoS Pathogens

CD4+T Cells: Differentiation and Functions

(2012) Rishi Vishal Luckheeram et al.   Clinical & Developmental Immunology

Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis

(2011) Tibor T. Glant et al.   ARTHRITIS AND RHEUMATISM

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

CEL-2000: A therapeutic vaccine for rheumatoid arthritis arrests disease development and alters serum cytokine/chemokine patterns in the bovine collagen type II induced arthritis in the DBA mouse model

(2010) Daniel H. Zimmerman et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

(2010) Helena S. Domingues et al.   PLoS One

J-LEAPS vaccines initiate murine Th1 responses by activating dendritic cells

(2010) P.R. Taylor et al.   VACCINE

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

(2009) Mary-Clare Miller et al.   ARTHRITIS AND RHEUMATISM

Control of Regulatory T Cell Lineage Commitment and Maintenance

(2009) Steven Z. Josefowicz et al.   IMMUNITY

Common themes emerge in the transcriptional control of T helper and developmental cell fate decisions regulated by the T-box, GATA and ROR families

(2009) Sara A. Miller et al.   IMMUNOLOGY

L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart

(2008) Daniela Cihakova et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

(2008) Dror Luger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination

(2008) Brian A Kidd et al.   ARTHRITIS RESEARCH & THERAPY