Central administration of sodium-glucose cotransporter-2 inhibitors increases food intake involving adenosine monophosphate-activated protein kinase phosphorylation in the lateral hypothalamus in healthy rats

Sodium/glucose cotransporter 2 is expressed in choroid plexus epithelial cells and ependymal cells in human and mouse brains

(2020) Yoichi Chiba et al.   NEUROPATHOLOGY

Dapagliflozin Activates Neurons in the Central Nervous System and Regulates Cardiovascular Activity by Inhibiting SGLT-2 in Mice

(2020) Thiquynhnga Nguyen et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Lateral but not Medial Hypothalamic AMPK Activation Occurs at the Hypoglycemic Nadir in Insulin-injected Male Rats: Impact of Caudal Dorsomedial Hindbrain Catecholamine Signaling

(2018) Hussain N. Alhamami et al.   NEUROSCIENCE

Validation of sodium/glucose cotransporter proteins in human brain as a potential marker for temporal narrowing of the trauma formation

(2018) Sabrina Oerter et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Putative tissue location and function of the SLC5 family member SGLT3

(2017) Matúš Soták et al.   EXPERIMENTAL PHYSIOLOGY

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

(2017) Daniel Garcia et al.   MOLECULAR CELL

Time-dependent effects of ipragliflozin on behaviour and energy homeostasis in normal and type 2 diabetic rats: continuous glucose telemetry analysis

(2017) Hiroyuki Iuchi et al.   Scientific Reports

Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice

(2016) Monica Sala-Rabanal et al.   JOURNAL OF PHYSIOLOGY-LONDON

How Strongly Does Appetite Counter Weight Loss? Quantification of the Feedback Control of Human Energy Intake

(2016) David Polidori et al.   Obesity

GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters

(2016) Dong Deng et al.   PROTEIN SCIENCE

Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy (DURATION-8): a 28 week, multicentre, double-blind, phase 3, randomised controlled trial

(2016) Juan P Frías et al.   Lancet Diabetes & Endocrinology

Energy Balance After Sodium–Glucose Cotransporter 2 Inhibition

(2015) Giulia Ferrannini et al.   DIABETES CARE

Mediobasal hypothalamic PTEN modulates hepatic insulin resistance independently of food intake in rats

(2014) Takashi Sumita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Stimulation of feeding by three different glucose-sensing mechanisms requires hindbrain catecholamine neurons

(2014) Ai-Jun Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Localizations of Na+-d-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart

(2014) Ivana Vrhovac et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Tofogliflozin, a sodium/glucose cotransporter 2 inhibitor, attenuates body weight gain and fat accumulation in diabetic and obese animal models

(2014) M Suzuki et al.   Nutrition & Diabetes

GLP-1 receptor agonists: a review of head-to-head clinical studies

(2014) Jennifer M. Trujillo et al.   Therapeutic Advances in Endocrinology and Metabolism

Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet

(2014) Steven P Vickers et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

The SLC2 (GLUT) family of membrane transporters

(2013) Mike Mueckler et al.   MOLECULAR ASPECTS OF MEDICINE

Glucagon-Like Peptide 1 (GLP-1) Can Reverse AMP-Activated Protein Kinase (AMPK) and S6 Kinase (P70S6K) Activities Induced by Fluctuations in Glucose Levels in Hypothalamic Areas Involved in Feeding Behaviour

(2012) Verónica Hurtado-Carneiro et al.   MOLECULAR NEUROBIOLOGY

Weight Loss Induced by Chronic Dapagliflozin Treatment Is Attenuated by Compensatory Hyperphagia in Diet-Induced Obese (DIO) Rats

(2012) James J. Devenny et al.   Obesity

Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors

(2011) R. Grempler et al.   DIABETES OBESITY & METABOLISM

Biology of Human Sodium Glucose Transporters

(2011) Ernest M. Wright et al.   PHYSIOLOGICAL REVIEWS

Functional expression of SGLTs in rat brain

(2010) Amy S. Yu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

SGLT2 Mediates Glucose Reabsorption in the Early Proximal Tubule

(2010) V. Vallon et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members

(2010) Jian Chen et al.   Diabetes Therapy

Dissociation between sensing and metabolism of glucose in sugar sensing neurones

(2008) J. Antonio Gonzàlez et al.   JOURNAL OF PHYSIOLOGY-LONDON