Biology of Human Sodium Glucose Transporters

Sodium-Dependent Glucose Transporter-1 as a Novel Immunological Player in the Intestinal Mucosa

(2014) M. Palazzo et al.   JOURNAL OF IMMUNOLOGY

Functional expression of SGLTs in rat brain

(2010) Amy S. Yu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Glucose transport by human renal Na+/d-glucose cotransporters SGLT1 and SGLT2

(2010) Charles S. Hummel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Water Permeation through the Sodium-Dependent Galactose Cotransporter vSGLT

(2010) Seungho Choe et al.   BIOPHYSICAL JOURNAL

The mechanism of sodium and substrate release from the binding pocket of vSGLT

(2010) Akira Watanabe et al.   NATURE

A Single Amino Acid Change Converts the Sugar Sensor SGLT3 into a Sugar Transporter

(2010) Laura Bianchi et al.   PLoS One

Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1

(2010) T. Shimamura et al.   SCIENCE

O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors

(2009) Baihua Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Ion-Releasing State of a Secondary Membrane Transporter

(2009) Jing Li et al.   BIOPHYSICAL JOURNAL

Phase I clinical and pharmacokinetic study of the glucose-conjugated cytotoxic agent d-19575 (glufosfamide) in patients with solid tumors

(2009) Toshio Shimizu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Dapagliflozin, a Novel SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects

(2009) B Komoroski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Dapagliflozin, a Novel, Selective SGLT2 Inhibitor, Improved Glycemic Control Over 2 Weeks in Patients With Type 2 Diabetes Mellitus

(2009) B Komoroski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Structure and function of Na+-symporters with inverted repeats

(2009) Jeff Abramson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Development of the Renal Glucose Reabsorption Inhibitors: A New Mechanism for the Pharmacotherapy of Diabetes Mellitus Type 2

(2009) William N. Washburn   JOURNAL OF MEDICINAL CHEMISTRY

Involvement of Amino Acid 36 in TM1 in Voltage Sensitivity in Mouse Na+/Glucose Cotransporter SGLT1

(2009) Ana Díez-Sampedro   JOURNAL OF MEMBRANE BIOLOGY

Water-Transporting Proteins

(2009) Thomas Zeuthen   JOURNAL OF MEMBRANE BIOLOGY

Na+-Glucose Cotransporter SGLT1 Protein in Salivary Glands: Potential Involvement in the Diabetes-Induced Decrease in Salivary Flow

(2009) R. Sabino-Silva et al.   JOURNAL OF MEMBRANE BIOLOGY

Expression Profiling of the Solute Carrier Gene Family in the Mouse Brain

(2009) A. Dahlin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Structure of a prokaryotic virtual proton pump at 3.2 Å resolution

(2009) Yiling Fang et al.   NATURE

Molecular basis of transport and regulation in the Na+/betaine symporter BetP

(2009) Susanne Ressl et al.   NATURE

Structure and Mechanism of an Amino Acid Antiporter

(2009) X. Gao et al.   SCIENCE

Revised immunolocalization of the Na+-d-glucose cotransporter SGLT1 in rat organs with an improved antibody

(2008) Daniela Balen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells

(2008) Xiaobo Lin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Reanalysis of structure/function correlations in the region of transmembrane segments 4 and 5 of the rabbit sodium/glucose cotransporter

(2008) Tiemin Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

(2008) Zhang Weihua et al.   CANCER CELL

Expression of SGLT1, Bcl-2 and p53 in Primary Pancreatic Cancer Related to Survival

(2008) Veerle F. Casneuf et al.   CANCER INVESTIGATION

Sodium-Glucose Cotransport Inhibition With Dapagliflozin in Type 2 Diabetes

(2008) J. F. List et al.   DIABETES CARE

Nephrocalcinosis in glucose-galactose malabsorption: nephrocalcinosis and proximal tubular dysfunction in a young infant with a novel mutation of SGLT1

(2008) Özlem Bekem Soylu et al.   EUROPEAN JOURNAL OF PEDIATRICS

SGLT-1-mediated glucose uptake protects human intestinal epithelial cells against Giardia duodenalis-induced apoptosis

(2008) Linda C.H. Yu et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

(2008) Wei Meng et al.   JOURNAL OF MEDICINAL CHEMISTRY

How Drugs Interact with Transporters: SGLT1 as a Model

(2008) Donald D. F. Loo et al.   JOURNAL OF MEMBRANE BIOLOGY

Engineering Protein Allostery: 1.05 Å Resolution Structure and Enzymatic Properties of a Na+-activated Trypsin

(2008) Michael J. Page et al.   JOURNAL OF MOLECULAR BIOLOGY

Control of Ion Selectivity in LeuT: Two Na+ Binding Sites with Two Different Mechanisms

(2008) Sergei Y. Noskov et al.   JOURNAL OF MOLECULAR BIOLOGY

Dissociation between sensing and metabolism of glucose in sugar sensing neurones

(2008) J. Antonio Gonzàlez et al.   JOURNAL OF PHYSIOLOGY-LONDON

Twenty-one additional cases of familial renal glucosuria: absence of genetic heterogeneity, high prevalence of private mutations and further evidence of volume depletion

(2008) J. Calado et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

(2008) S. Weyand et al.   SCIENCE

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

(2008) S. Faham et al.   SCIENCE