Compliant Substrates Enhance Macrophage Cytokine Release and NLRP3 Inflammasome Formation During Their Pro-Inflammatory Response

Tumor-Associated Macrophages: Recent Insights and Therapies

(2020) Jiawei Zhou et al.   Frontiers in Oncology

Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion

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Matrix stiffness‐mediated effects on macrophages polarization and their LOXL2 expression

(2020) Xiaoxia Xing et al.   FEBS Journal

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation

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Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration

(2019) William Y. Wang et al.   Nature Communications

Material stiffness influences the polarization state, function and migration mode of macrophages

(2019) Rukmani Sridharan et al.   Acta Biomaterialia

The plasma membrane as a mechanochemical transducer

(2019) Anabel-Lise Le Roux et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

NF-κB Signaling in Macrophages: Dynamics, Crosstalk, and Signal Integration

(2019) Michael G. Dorrington et al.   Frontiers in Immunology

ilastik: interactive machine learning for (bio)image analysis

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Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression

(2018) Takayuki Okamoto et al.   EXPERIMENTAL CELL RESEARCH

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

(2018) Charles L. Evavold et al.   IMMUNITY

Toll-like receptor signaling in macrophages is regulated by extracellular substrate stiffness and Rho-associated coiled-coil kinase (ROCK1/2)

(2018) Erika Gruber et al.   INTERNATIONAL IMMUNOLOGY

Interstitial Flow Promotes Macrophage Polarization toward an M2 Phenotype

(2018) Ran Li et al.   MOLECULAR BIOLOGY OF THE CELL

Control of Mechanotransduction by Molecular Clutch Dynamics

(2018) Alberto Elosegui-Artola et al.   TRENDS IN CELL BIOLOGY

Cyclic Stretch Negatively Regulates IL-1β Secretion Through the Inhibition of NLRP3 Inflammasome Activation by Attenuating the AMP Kinase Pathway

(2018) Kentaro Maruyama et al.   Frontiers in Physiology

Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review

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Spatial confinement downsizes the inflammatory response of macrophages

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Interleukin-18: Biological properties and role in disease pathogenesis

(2017) Gilles Kaplanski   IMMUNOLOGICAL REVIEWS

Inflammasome activation and assembly at a glance

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Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation

(2017) Irena L. Ivanovska et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative Assessment of Skin Stiffness in Localized Scleroderma Using Ultrasound Shear-Wave Elastography

(2017) Liyun Wang et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Bioconjugating Thiols to Poly(acrylamide) Gels for Cell Culture Using Methylsulfonyl Co-monomers

(2016) Aleeza Farrukh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanical properties of cortical bone and their relationships with age, gender, composition and microindentation properties in the elderly

(2016) Mohammad J. Mirzaali et al.   BONE

Effect of M1–M2 Polarization on the Motility and Traction Stresses of Primary Human Macrophages

(2016) Laurel E. Hind et al.   Cellular and Molecular Bioengineering

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggression

(2016) Yekaterina A. Miroshnikova et al.   NATURE CELL BIOLOGY

F-actin dampens NLRP3 inflammasome activity via Flightless-I and LRRFIP2

(2016) Danielle Burger et al.   Scientific Reports

Materials and technologies for soft implantable neuroprostheses

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Substrate elasticity regulates the behavior of human monocyte-derived macrophages

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Macrophage motility is driven by frontal-towing with a force magnitude dependent on substrate stiffness

(2015) Laurel E. Hind et al.   Integrative Biology

TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis

(2015) Rachel G. Scheraga et al.   JOURNAL OF IMMUNOLOGY

Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation

(2015) W. K. Eddie Ip et al.   Nature Communications

Vimentin regulates activation of the NLRP3 inflammasome

(2015) Gimena dos Santos et al.   Nature Communications

Substrate Stiffness Regulates Proinflammatory Mediator Production through TLR4 Activity in Macrophages

(2015) Michelle L. Previtera et al.   PLoS One

The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system

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Actin polymerization as a key innate immune effector mechanism to controlSalmonellainfection

(2014) Si Ming Man et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin–microtubule coordination at growing microtubule ends

(2014) Magdalena Preciado López et al.   Nature Communications

Tissue mechanics and fibrosis

(2013) Rebecca G. Wells   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Modulation of macrophage phenotype by cell shape

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Acellular Normal and Fibrotic Human Lung Matrices as a Culture System forIn VitroInvestigation

(2012) Adam J. Booth et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Cell Elasticity Determines Macrophage Function

(2012) Naimish R. Patel et al.   PLoS One

A clinical perspective of IL-1β as the gatekeeper of inflammation

(2011) Charles A. Dinarello   EUROPEAN JOURNAL OF IMMUNOLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy

(2010) Andreas F. Christ et al.   JOURNAL OF BIOMECHANICS

Age-Dependent Regional Mechanical Properties of the Rat Hippocampus and Cortex

(2009) Benjamin S. Elkin   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Non-invasive measurement of brain viscoelasticity using magnetic resonance elastography

(2007) Ingolf Sack et al.   NMR IN BIOMEDICINE