The Dual Role of STAT1 in Ovarian Cancer: Insight Into Molecular Mechanisms and Application Potentials
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Title
The Dual Role of STAT1 in Ovarian Cancer: Insight Into Molecular Mechanisms and Application Potentials
Authors
Keywords
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Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-03-23
DOI
10.3389/fcell.2021.636595
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Related references
Note: Only part of the references are listed.- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- TGF-β Signaling
- (2020) Kalliopi Tzavlaki et al. Biomolecules
- Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells
- (2020) Fanchen Wang et al. Aging-US
- Expression of STAT1 is positively correlated with PD-L1 in human ovarian cancer
- (2020) Fangran Liu et al. CANCER BIOLOGY & THERAPY
- IL-10 derived from M2 macrophage promotes cancer stemness via JAK1/STAT1/NF-κB/Notch1 pathway in non-small cell lung cancer
- (2019) Li Yang et al. INTERNATIONAL JOURNAL OF CANCER
- IL-21 reinvigorates exhausted natural killer cells in patients with HBV-associated hepatocellular carcinoma in STAT1-depedent pathway
- (2019) Yun Jin et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The Potential Role of iNOS in Ovarian Cancer Progression and Chemoresistance
- (2019) Kielbik et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis
- (2019) Yang Hao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Warburg effect and its role in tumourigenesis
- (2019) Maphuti T. Lebelo et al. ARCHIVES OF PHARMACAL RESEARCH
- Ovarian cancer statistics, 2018
- (2018) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer
- (2018) Nicholas S. Akins et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- CD8 + CXCR5 + T cells in tumor-draining lymph nodes are highly activated and predict better prognosis in colorectal cancer
- (2018) Jifu E et al. HUMAN IMMUNOLOGY
- Increased STAT1 Expression in High Grade Serous Ovarian Cancer Is Associated With a Better Outcome
- (2018) Juliana A. Josahkian et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Targetable Immune Regulatory Molecule Expression in High-Grade Serous Ovarian Carcinomas in African American Women
- (2018) Anne M. Mills et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
- Molecular mechanisms of drug resistance in ovarian cancer
- (2018) Leyla Norouzi-Barough et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Physical interaction of STAT1 isoforms with TGF-β receptors leads to functional crosstalk between two signaling pathways in epithelial ovarian cancer
- (2018) Xiaoling Tian et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Ovarian Cancer
- (2018) Ursula A. Matulonis HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies
- (2018) Catherine Rolvering et al. JOURNAL OF LEUKOCYTE BIOLOGY
- STAT1‑HDAC4 signaling induces epithelial‑mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2
- (2018) Sirichat Kaowinn et al. ONCOLOGY REPORTS
- The molecular details of cytokine signalling via the JAK/STAT pathway
- (2018) Rhiannon Morris et al. PROTEIN SCIENCE
- Diagnosing ovarian cancer
- (2018) Melissa Walker et al. CANADIAN MEDICAL ASSOCIATION JOURNAL
- Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis
- (2018) Sheng-Fan Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ovarian cancer stem cell: A potential therapeutic target for overcoming multidrug resistance
- (2018) Aynaz Mihanfar et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Tumour microenvironment and metabolic plasticity in cancer and cancer stem cells: Perspectives on metabolic and immune regulatory signatures in chemoresistant ovarian cancer stem cells
- (2018) Nuzhat Ahmed et al. SEMINARS IN CANCER BIOLOGY
- CCNG1 (Cyclin G1) regulation by mutant-P53 via induction of Notch3 expression promotes high-grade serous ovarian cancer (HGSOC) tumorigenesis and progression
- (2018) Ying Xu et al. Cancer Medicine
- The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment
- (2018) Matthias Parrini et al. Frontiers in Immunology
- ISG15 Promotes ERK1 ISGylation, CD8+ T Cell Activation and Suppresses Ovarian Cancer Progression
- (2018) Tsz-Lun Yeung et al. Cancers
- CXCL10 alters the tumour immune microenvironment and disease progression in a syngeneic murine model of high-grade serous ovarian cancer
- (2017) Katrina K. Au et al. GYNECOLOGIC ONCOLOGY
- Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon α-mediated inhibition of angiogenesis
- (2017) Kuo-Sheng Hsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Upregulation of IGF1 by tumor-associated macrophages promotes the proliferation and migration of epithelial ovarian cancer cells
- (2017) Li Liu et al. ONCOLOGY REPORTS
- Epigenetics in ovarian cancer
- (2017) Yanina Natanzon et al. SEMINARS IN CANCER BIOLOGY
- iNOS-derived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancer
- (2017) Linlin Li et al. Oncotarget
- Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines
- (2017) Radosław Januchowski et al. Oncotarget
- CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response
- (2017) Abdul S. Qadir et al. Cell Reports
- miR-2909 regulates ISGylation system via STAT1 signalling through negative regulation of SOCS3 in prostate cancer
- (2017) Shiekh Gazalla Ayub et al. Andrology
- Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation
- (2017) Ioana I. Nitulescu et al. EBioMedicine
- Global trends and predictions in ovarian cancer mortality
- (2016) M. Malvezzi et al. ANNALS OF ONCOLOGY
- Glycolysis inhibition as a cancer treatment and its role in an anti-tumour immune response
- (2016) Kheshwant S. Gill et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer
- (2016) Holger Bronger et al. BRITISH JOURNAL OF CANCER
- CD24 suppresses malignant phenotype by downregulation of SHH transcription through STAT1 inhibition in breast cancer cells
- (2016) Kumi Suyama et al. CANCER LETTERS
- Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer
- (2016) Weimin Wang et al. CELL
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
- (2016) David H. Munn et al. TRENDS IN IMMUNOLOGY
- Proteomic analysis uncovers common effects of IFN-γ and IL-27 on the HLA class I antigen presentation machinery in human cancer cells
- (2016) Andrea Petretto et al. Oncotarget
- Bortezomib Relieves Immune Tolerance in Nasopharyngeal Carcinoma via STAT1 Suppression and Indoleamine 2,3-Dioxygenase Downregulation
- (2016) Guan-Min Jiang et al. Cancer Immunology Research
- A distinct pre-existing inflammatory tumour microenvironment is associated with chemotherapy resistance in high-grade serous epithelial ovarian cancer
- (2015) M Koti et al. BRITISH JOURNAL OF CANCER
- The role of ABC transporters in ovarian cancer progression and chemoresistance
- (2015) M.P. Ween et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- AG490, a Jak2 inhibitor, suppressed the progression of murine ovarian cancer
- (2015) Aya Kobayashi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Structural Basis of the Inhibition of STAT1 Activity by Sendai Virus C Protein
- (2015) Kosuke Oda et al. JOURNAL OF VIROLOGY
- The homeoprotein DLX4 controls inducible nitric oxide synthase-mediated angiogenesis in ovarian cancer
- (2015) Bon Trinh et al. Molecular Cancer
- Inhibition of integrin β1 decreases the malignancy of ovarian cancer cells and potentiates anticancer therapy via the FAK/STAT1 signaling pathway
- (2015) LEI ZHANG et al. Molecular Medicine Reports
- Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
- (2015) Dongjun Peng et al. NATURE
- Mutations in the linker domain affect phospho-STAT3 function and suggest targets for interrupting STAT3 activity
- (2015) Claudia Mertens et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-27 induces the expression of IDO and PD-L1 in human cancer cells
- (2015) Grazia Carbotti et al. Oncotarget
- Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis
- (2015) Rajesha Rupaimoole et al. Cell Reports
- CXCR2 Inhibition Combined with Sorafenib Improved Antitumor and Antiangiogenic Response in Preclinical Models of Ovarian Cancer
- (2015) Bharat Devapatla et al. PLoS One
- Activation of Integrin β1 Mediates the Increased Malignant Potential of Ovarian Cancer Cells Exerted by Inflammatory Cytokines
- (2014) Zongyuan Yang et al. Anti-Cancer Agents in Medicinal Chemistry
- Immune Escape Mechanisms as a Guide for Cancer Immunotherapy
- (2014) G. L. Beatty et al. CLINICAL CANCER RESEARCH
- Expression of IL-18, IL-18 Binding Protein, and IL-18 Receptor by Normal and Cancerous Human Ovarian Tissues: Possible Implication of IL-18 in the Pathogenesis of Ovarian Carcinoma
- (2014) Liat Medina et al. MEDIATORS OF INFLAMMATION
- STAT1 Is Not Dominant Negative and Is Capable of Contributing to Gamma Interferon-Dependent Innate Immunity
- (2014) C. Semper et al. MOLECULAR AND CELLULAR BIOLOGY
- Overexpression of astrocyte-elevated gene-1 is associated with ovarian cancer development and progression
- (2014) BO ZHOU et al. Molecular Medicine Reports
- Tackling the cancer stem cells — what challenges do they pose?
- (2014) Diwakar R. Pattabiraman et al. NATURE REVIEWS DRUG DISCOVERY
- CD95 and CD95L promote and protect cancer stem cells
- (2014) Paolo Ceppi et al. Nature Communications
- Interferon-γ produced by tumor-infiltrating NK cells and CD4+ T cells downregulates TNFSF15 expression in vascular endothelial cells
- (2013) Yi Lu et al. ANGIOGENESIS
- The IL-18 Antagonist IL-18-Binding Protein Is Produced in the Human Ovarian Cancer Microenvironment
- (2013) G. Carbotti et al. CLINICAL CANCER RESEARCH
- CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response
- (2013) Joanna Bancerek et al. IMMUNITY
- Mini-review on Glycolysis and Cancer
- (2013) M. Akram JOURNAL OF CANCER EDUCATION
- Role of Glutathione in Cancer Progression and Chemoresistance
- (2013) Nicola Traverso et al. Oxidative Medicine and Cellular Longevity
- The Ratios of CD8+ T Cells to CD4+CD25+ FOXP3+ and FOXP3- T Cells Correlate with Poor Clinical Outcome in Human Serous Ovarian Cancer
- (2013) Claudia C. Preston et al. PLoS One
- Phosphorylation of signal transducer and activator of transcription 1 reduces bortezomib-mediated apoptosis in cancer cells
- (2013) C Kao et al. Cell Death & Disease
- Targeting the hallmarks of cancer
- (2012) Pierre Hainaut et al. CURRENT OPINION IN ONCOLOGY
- The JAK-STAT Pathway at Twenty
- (2012) George R. Stark et al. IMMUNITY
- The emerging role of CXC chemokines in epithelial ovarian cancer
- (2012) Adam Rainczuk et al. REPRODUCTION
- Down-modulation of TNFSF15 in ovarian cancer by VEGF and MCP-1 is a pre-requisite for tumor neovascularization
- (2011) Weimin Deng et al. ANGIOGENESIS
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- HDAC4-Regulated STAT1 Activation Mediates Platinum Resistance in Ovarian Cancer
- (2011) E. A. Stronach et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- CXCR3 in T cell function
- (2011) Joanna R. Groom et al. EXPERIMENTAL CELL RESEARCH
- Serum Tryptophan and Kynurenine Concentrations as Parameters for Indoleamine 2,3-Dioxygenase Activity in Patients With Endometrial, Ovarian, and Vulvar Cancer
- (2011) Renske A. de Jong et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy
- (2011) DONGDONG WANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Novel TGF- Antagonist Inhibits Tumor Growth and Angiogenesis by Inducing IL-2 Receptor-Driven STAT1 Activation
- (2011) C. Penafuerte et al. JOURNAL OF IMMUNOLOGY
- Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node metastasis in triple-negative breast cancer
- (2011) Christina Greenwood et al. Journal of Proteomics
- Regulatory T Cells and IL-10 Independently Counterregulate Cytotoxic T Lymphocyte Responses Induced by Transcutaneous Immunization
- (2011) Pamela Stein et al. PLoS One
- An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
- (2010) J. D. Mezrich et al. JOURNAL OF IMMUNOLOGY
- STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect
- (2009) Sean P Pitroda et al. BMC Medicine
- BeyondBRCA1andBRCA2wild-type breast and/or ovarian cancer families: germline mutations inTP53andPTEN
- (2009) A Blanco et al. CLINICAL GENETICS
- Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains
- (2009) Jonathan M Wojciak et al. EMBO JOURNAL
- A phase II evaluation of bortezomib in the treatment of recurrent platinum-sensitive ovarian or primary peritoneal cancer: A Gynecologic Oncology Group study
- (2009) Carol Aghajanian et al. GYNECOLOGIC ONCOLOGY
- Identification of Genes With Differential Expression in Chemoresistant Epithelial Ovarian Cancer Using High-Density Oligonucleotide Microarrays
- (2009) Woong Ju et al. ONCOLOGY RESEARCH
- Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: involvement in p53 regulation and cisplatin resistance
- (2008) E L Leung et al. BRITISH JOURNAL OF CANCER
- Guanylate binding protein-1 inhibits spreading and migration of endothelial cells through induction of integrin α4 expression
- (2008) Kristina Weinländer et al. FASEB JOURNAL
- Cross-talk between IFN-α and TGF-β1signaling pathways in preneoplastic rat liver
- (2008) María De Luján Alvarez* et al. GROWTH FACTORS
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