Sodium Valproate-Induced Chromatin Remodeling

Valproic acid influences the expression of genes implicated with hyperglycaemia-induced complement and coagulation pathways

(2021) Marina Barreto Felisbino et al.   Scientific Reports

Effects of sodium valproate on the chromatin of Triatoma infestans (Klug, 1834) (Hemiptera, Reduviidae) under in vitro culture conditions

(2021) Alessandra Bassani et al.   ACTA HISTOCHEMICA

Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal Differentiation

(2020) Surabhi Shukla et al.   Frontiers in Pharmacology

Combination of SB431542, CHIR99021 and PD0325901 has a synergic effect on abrogating valproic acid‑induced epithelial‑mesenchymal transition and stemness in HeLa, 5637 and SCC‑15 cells

(2019) Yanmin Zhang et al.   ONCOLOGY REPORTS

Single Cell Imaging of Nuclear Architecture Changes

(2019) Rikke Brandstrup Morrish et al.   Frontiers in Cell and Developmental Biology

Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells

(2019) Marina Amorim Rocha et al.   Scientific Reports

Challenges in application of Raman spectroscopy to biology and materials

(2018) Nikki Kuhar et al.   RSC Advances

Valproic acid as an adjunctive therapeutic agent for the treatment of breast cancer

(2018) Hayley Heers et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Spectroscopic analysis of the interaction of valproic acid with histone H1 in solution and in chromatin structure

(2017) Javad Sargolzaei et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Histone H3 Acetyl K9 and Histone H3 Tri Methyl K4 as Prognostic Markers for Patients with Cervical Cancer

(2017) Susanne Beyer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chromatin organization at the nuclear periphery as revealed by image analysis of structured illumination microscopy data

(2017) Jindřiška Fišerová et al.   JOURNAL OF CELL SCIENCE

HDAC inhibitors enhance the immunotherapy response of melanoma cells

(2017) Laurence Booth et al.   Oncotarget

DNA Methylation Changes in Valproic Acid-Treated HeLa Cells as Assessed by Image Analysis, Immunofluorescence and Vibrational Microspectroscopy

(2017) Giovana M. B. Veronezi et al.   PLoS One

Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells

(2014) Periyasamy Palsamy et al.   EXPERIMENTAL EYE RESEARCH

Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation

(2014) Brendan E. Russ et al.   IMMUNITY

HDAC inhibition through valproic acid modulates the methylation profiles in human embryonic kidney cells

(2014) Shabir Ahmad Ganai et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Changes in Chromatin Structure in NIH 3T3 Cells Induced by Valproic Acid and Trichostatin A

(2014) Marina Barreto Felisbino et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Changes in Liver Cell DNA Methylation Status in Diabetic Mice Affect Its FT-IR Characteristics

(2014) Benedicto de Campos Vidal et al.   PLoS One

Epigenetics and cervical cancer: from pathogenesis to therapy

(2014) Jinchuan Fang et al.   TUMOR BIOLOGY

Nuclear pore proteins regulate chromatin structure and transcriptional memory by a conserved mechanism

(2013) William H Light et al.   Nucleus

Valproic acid shows a potent antitumor effect with alteration of DNA methylation in neuroblastoma

(2012) Song Gu et al.   ANTI-CANCER DRUGS

Monitoring the reversible B to A-like transition of DNA in eukaryotic cells using Fourier transform infrared spectroscopy

(2011) Donna R. Whelan et al.   NUCLEIC ACIDS RESEARCH

A Pilot Phase II Study of Valproic Acid for Treatment of Low-Grade Neuroendocrine Carcinoma

(2011) T. A. Mohammed et al.   ONCOLOGIST

Chromatin Remodeling, Cell Proliferation and Cell Death in Valproic Acid-Treated HeLa Cells

(2011) Marina Barreto Felisbino et al.   PLoS One

Valproate induces DNA demethylation in nuclear extracts from adult mouse brain

(2010) Erbo Dong et al.   Epigenetics

Prognostic relevance of global histone H3 lysine 4 (H3K4) methylation in renal cell carcinoma

(2010) Jörg Ellinger et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular and Therapeutic Potential and Toxicity of Valproic Acid

(2010) Sébastien Chateauvieux et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Characterisation of DNA methylation status using spectroscopy (mid-IR versus Raman) with multivariate analysis

(2010) Jemma G. Kelly et al.   Journal of Biophotonics

Gamma Interferon-Dependent Transcriptional Memory via Relocalization of a Gene Locus to PML Nuclear Bodies

(2010) M. Gialitakis et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons

(2010) Zoya Marinova et al.   NEUROPHARMACOLOGY

Discrimination of Base Differences in Oligonucleotides Using Mid-Infrared Spectroscopy and Multivariate Analysis

(2009) Jemma G. Kelly et al.   ANALYTICAL CHEMISTRY

Valproic acid causes dose- and time-dependent changes in nuclear structure in prostate cancer cells in vitro and in vivo

(2009) M. S.Q. Kortenhorst et al.   MOLECULAR CANCER THERAPEUTICS

Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions

(2009) Mamoru Fukuchi et al.   NEUROSCIENCE RESEARCH

Solid-State Forms of Sodium Valproate, Active Component of the Anticonvulsant Drug Epilim

(2008) Gjorgi Petruševski et al.   ChemMedChem

Phase I Study of Epigenetic Modulation with 5-Azacytidine and Valproic Acid in Patients with Advanced Cancers

(2008) F. Braiteh et al.   CLINICAL CANCER RESEARCH

Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells

(2008) Marielle Dejligbjerg et al.   Molecular Cancer