Forsythoside A Alleviates High Glucose-Induced Oxidative Stress and Inflammation in Podocytes by Inactivating MAPK Signaling via MMP12 Inhibition

Silencing CCNG1 protects MPC-5 cells from high glucose-induced proliferation-inhibition and apoptosis-promotion via MDM2/p53 signaling pathway

(2020) Ye Chen et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

LncRNA ANRIL Silencing Alleviates High Glucose-Induced Inflammation, Oxidative Stress, and Apoptosis via Upregulation of MME in Podocytes

(2020) Ruiyu Cai et al.   INFLAMMATION

Histone deacetylase 4 mediates high glucose-induced podocyte apoptosis via upregulation of calcineurin

(2020) Wanxin Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Forsythoside A protects against lipopolysaccharide-induced acute lung injury through up-regulating microRNA-124

(2020) Zibin Lu et al.   CLINICAL SCIENCE

Mogroside IIIE Alleviates High Glucose-Induced Inflammation, Oxidative Stress and Apoptosis of Podocytes by the Activation of AMPK/SIRT1 Signaling Pathway

(2020) Wei Xue et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

The cirrhotic liver is depleted of docosahexaenoic acid (DHA), a key modulator of NF-κB and TGFβ pathways in hepatic stellate cells

(2019) Mónica Enguita et al.   Cell Death & Disease

MMP-12 regulates proliferation of mouse macrophages via the ERK/P38 MAPK pathways during inflammation

(2019) Chenyu Guan et al.   EXPERIMENTAL CELL RESEARCH

Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria

(2019) Lili Zhou et al.   KIDNEY INTERNATIONAL

The protective effect and mechanism of catalpol on high glucose-induced podocyte injury

(2019) Yan Chen et al.   BMC Complementary and Alternative Medicine

Crocin mediated amelioration of oxidative burden and inflammatory cascade suppresses diabetic nephropathy progression in diabetic rats

(2018) Hadeer O. Abou-Hany et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Forsythoside A inhibited S. aureus stimulated inflammatory response in primary bovine mammary epithelial cells

(2018) Jiali Zhang et al.   MICROBIAL PATHOGENESIS

Protective effects of Forsythoside A on amyloid beta-induced apoptosis in PC12 cells by downregulating acetylcholinesterase

(2017) Xiaojuan Yan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Forsythoside A exerts antipyretic effect on yeast-induced pyrexia mice via inhibiting transient receptor potential vanilloid 1 function

(2017) Cuiling Liu et al.   International Journal of Biological Sciences

Forsythoside A exerts an anti-endotoxin effect by blocking the LPS/TLR4 signaling pathway and inhibiting Tregs in vitro

(2017) Xiao-Yan Zeng et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Antiviral effect of forsythoside A from Forsythia suspensa (Thunb.) Vahl fruit against influenza A virus through reduction of viral M1 protein

(2017) Anna Hing-Yee Law et al.   JOURNAL OF ETHNOPHARMACOLOGY

PLK2 Plays an Essential Role in High D-Glucose-Induced Apoptosis, ROS Generation and Inflammation in Podocytes

(2017) Hong-hong Zou et al.   Scientific Reports

Salidroside Reduces High-Glucose-Induced Podocyte Apoptosis and Oxidative Stress via Upregulating Heme Oxygenase-1 (HO-1) Expression

(2017) Hua Lu et al.   MEDICAL SCIENCE MONITOR

Ursodeoxycholic Acid Ameliorated Diabetic Nephropathy by Attenuating Hyperglycemia-Mediated Oxidative Stress

(2016) Aili Cao et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Clinical Manifestations of Kidney Disease Among US Adults With Diabetes, 1988-2014

(2016) Maryam Afkarian et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 DiabetesSignificance

(2015) Isabel Goncalves et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pterostilbene and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377

(2015) Wei Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice

(2015) Hajime Nagasu et al.   LABORATORY INVESTIGATION

Forsythiaside A Exhibits Anti-inflammatory Effects in LPS-Stimulated BV2 Microglia Cells Through Activation of Nrf2/HO-1 Signaling Pathway

(2015) Yue Wang et al.   NEUROCHEMICAL RESEARCH

Macrophage metalloelastase-12 is detectable in human seminal plasma and represents a predictor for inflammatory processes in the male genital tract

(2014) A. Urbschat et al.   ANDROLOGIA

Nox family NADPH oxidases: Molecular mechanisms of activation

(2014) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molecular and Cellular Events Mediating Glomerular Podocyte Dysfunction and Depletion in Diabetes Mellitus

(2014) P. Anil Kumar et al.   Frontiers in Endocrinology

Epidemiology of Diabetic Kidney Disease

(2013) Anne T. Reutens   MEDICAL CLINICS OF NORTH AMERICA

Pycnogenol modulates apoptosis by suppressing oxidative stress and inflammation in high glucose-treated renal tubular cells

(2011) You Jung Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Therapeutic Modalities in Diabetic Nephropathy: Standard and Emerging Approaches

(2011) Emaad M. Abdel-Rahman et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

Renal Dysfunction in the Presence of Normoalbuminuria in Type 2 Diabetes: Results from the DEMAND Study

(2011) Jamie P. Dwyer et al.   CardioRenal Medicine

Protective effects of Forsythia suspensa extract against oxidative stress induced by diquat in rats

(2009) T. Lu et al.   FOOD AND CHEMICAL TOXICOLOGY

Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

(2008) C. C. Berthier et al.   DIABETES

Antioxidant and antibacterial activity of two compounds (forsythiaside and forsythin) isolated fromForsythia suspensa

(2008) Huanhuan Qu et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY