The protective effect and mechanism of catalpol on high glucose-induced podocyte injury

miR‐15b‐5p ameliorated high glucose‐induced podocyte injury through repressing apoptosis, oxidative stress, and inflammatory responses by targeting Sema3A

(2019) Yanqin Fu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Icariin modulates mitochondrial function and apoptosis in high glucose-induced glomerular podocytes through G protein-coupled estrogen receptors

(2018) Chen Qiao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Salvia przewalskii extract of total phenolic acids inhibit TLR4 signaling activation in podocyte injury induced by puromycin aminonucleoside in vitro

(2018) Hongqi Ren et al.   RENAL FAILURE

Taiwanese Green Propolis Ethanol Extract Delays the Progression of Type 2 Diabetes Mellitus in Rats Treated with Streptozotocin/High-Fat Diet

(2018) Li-Han Chen et al.   Nutrients

Genistein and Myd88 Activate Autophagy in High Glucose-Induced Renal Podocytes In Vitro

(2018) Yuanyuan Wang et al.   MEDICAL SCIENCE MONITOR

miR-423-5p suppresses high-glucose-induced podocyte injury by targeting Nox4

(2018) Yuxiang Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Down-regulation of microRNA-21 reduces inflammation and podocyte apoptosis in diabetic nephropathy by relieving the repression of TIMP3 expression

(2018) Xiaoping Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Knockdown of TLR4 attenuates high glucose-induced podocyte injury via the NALP3/ASC/Caspase-1 signaling pathway

(2018) Yang Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Mechanism of Lakoochin A Inducing Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS and MAPKs Pathway

(2018) Kuo-Ti Peng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MiR-874 alleviates renal injury and inflammatory response in diabetic nephropathy through targeting toll-like receptor-4

(2018) Tao Yao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

2-Phenylacetamide Isolated from the Seeds of Lepidium apetalum and Its Estrogen-Like Effects In Vitro and In Vivo

(2018) Mengnan Zeng et al.   MOLECULES

Astragaloside IV/lncRNA-TUG1/TRAF5 signaling pathway participates in podocyte apoptosis of diabetic nephropathy rats

(2018) Xiao Lei et al.   Drug Design Development and Therapy

Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells

(2018) Huimin Hu et al.   INFLAMMATION

Celastrol antagonizes high glucose-evoked podocyte injury, inflammation and insulin resistance by restoring the HO-1-mediated autophagy pathway

(2018) Xiaojiang Zhan et al.   MOLECULAR IMMUNOLOGY

Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway

(2018) Yuan Wang et al.   Drug Design Development and Therapy

Beneficial Effects of Small Molecule Oligopeptides Isolated from Panax ginseng Meyer on Pancreatic Beta-Cell Dysfunction and Death in Diabetic Rats

(2017) Meihong Xu et al.   Nutrients

Puerarin attenuates diabetic kidney injury through the suppression of NOX4 expression in podocytes

(2017) Xueling Li et al.   Scientific Reports

Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury

(2017) Selim Fakhruddin et al.   Journal of Diabetes Research

The effects of selenium supplementation on biomarkers of inflammation and oxidative stress in patients with diabetic nephropathy: a randomised, double-blind, placebo-controlled trial

(2016) Fereshteh Bahmani et al.   BRITISH JOURNAL OF NUTRITION

Pretreatment with Astragaloside IV protects human umbilical vein endothelial cells from hydrogen peroxide induced oxidative stress and cell dysfunction via inhibiting eNOS uncoupling and NADPH oxidase – ROS – NF-κB pathway

(2016) Chonghua Xu et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Amelioration of Diabetic Mouse Nephropathy by Catalpol Correlates with Down-Regulation of Grb10 Expression and Activation of Insulin-Like Growth Factor 1 / Insulin-Like Growth Factor 1 Receptor Signaling

(2016) Shasha Yang et al.   PLoS One

Oxidative Stress in Diabetic Nephropathy with Early Chronic Kidney Disease

(2016) Alejandra Guillermina Miranda-Díaz et al.   Journal of Diabetes Research

Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy

(2015) Atsuko Tagawa et al.   DIABETES

Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing MAPK mediated inflammatory responses and oxidative stress

(2015) Jinglou Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Molecular mechanisms of diabetic kidney disease

(2014) Kimberly Reidy et al.   JOURNAL OF CLINICAL INVESTIGATION

Global toll-like receptor 4 knockout results in decreased renal inflammation, fibrosis and podocytopathy

(2014) Ishwarlal Jialal et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Aldosterone induces C-reactive protein expression via MR-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells

(2014) Xiaolu Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Neuroprotective activities of catalpol against CaMKII-dependent apoptosis induced by LPS in PC12 cells

(2013) Wenna Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Resveratrol Attenuates Oxidative Stress Induced by Balloon Injury in the Rat Carotid Artery Through Actions on the ERK1/2 and NF-Kappa B Pathway

(2013) Jing Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Catalpol suppresses advanced glycation end-products-induced inflammatory responses through inhibition of reactive oxygen species in human monocytic THP-1 cells

(2013) Hee-Jung Choi et al.   FITOTERAPIA

Chronic kidney disease: global dimension and perspectives

(2013) Vivekanand Jha et al.   LANCET

Diabetic nephropathy: diagnosis and treatment

(2013) Daniel Fineberg et al.   Nature Reviews Endocrinology

Effect of catalpol on diabetic nephropathy in rats

(2013) Zhao Dong et al.   PHYTOMEDICINE

Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy

(2012) E. Jennifer Weil et al.   KIDNEY INTERNATIONAL

Catalpol inhibits LPS plus IFN-γ-induced inflammatory response in astrocytes primary cultures

(2012) Jing Bi et al.   TOXICOLOGY IN VITRO

Podocyte Detachment in Type 2 Diabetic Nephropathy

(2011) E. Jennifer Weil et al.   AMERICAN JOURNAL OF NEPHROLOGY

Cell Biology and Pathology of Podocytes

(2011) Anna Greka et al.   Annual Review of Physiology

The podocyte as a target for therapies—new and old

(2011) Peter W. Mathieson   Nature Reviews Nephrology

Transcription factors in the pathogenesis of diabetic nephropathy

(2009) Amber Paratore Sanchez et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Advanced oxidation protein products: a causative link between oxidative stress and podocyte depletion

(2009) Youhua Liu   KIDNEY INTERNATIONAL

Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

(2008) C. C. Berthier et al.   DIABETES

Podocyte-Specific Overexpression of the Antioxidant Metallothionein Reduces Diabetic Nephropathy

(2008) S. Zheng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte injury in focal segmental glomerulosclerosis: Lessons from animal models (a play in five acts)

(2007) V.D. D'Agati   KIDNEY INTERNATIONAL