Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells

Dyslipidemia at diagnosis of childhood acute lymphoblastic leukemia

(2020) Pernille Rudebeck Mogensen et al.   PLoS One

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

(2020) Martin Paré et al.   BMC CANCER

Cancer-associated adipocytes: key players in breast cancer progression

(2019) Qi Wu et al.   Journal of Hematology & Oncology

Precision biomarker discovery powered by microscopy image fusion-assisted high spatial resolution ambient ionization mass spectrometry imaging

(2019) Li-En Lin et al.   ANALYTICA CHIMICA ACTA

The identification and pharmacological evaluation of potent, selective and orally available ACC1 inhibitor

(2019) Ryo Mizojiri et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lipid droplets induced by secreted phospholipase A 2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress

(2018) Eva Jarc et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Orlistat as a FASN inhibitor and multitargeted agent for cancer therapy

(2018) Alejandro Schcolnik-Cabrera et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

A reversible carnitine palmitoyltransferase I (CPT1) inhibitor offsets chronic lymphocytic leukemia cell proliferation

(2018) Elena Gugiatti et al.   HAEMATOLOGICA

A reversible carnitine palmitoyltransferase I (CPT1) inhibitor offsets chronic lymphocytic leukemia cell proliferation

(2018) Elena Gugiatti et al.   HAEMATOLOGICA

Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin

(2017) Xia Sheng et al.   MOLECULAR CANCER RESEARCH

Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells

(2017) Takashi Okumura et al.   Oncotarget

Association of body mass index and survival in pediatric leukemia: a meta-analysis

(2016) Etan Orgel et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Stearoyl CoA desaturase-1: New insights into a central regulator of cancer metabolism

(2016) R. Ariel Igal   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Pinolenic Acid Downregulates Lipid Anabolic Pathway in HepG2 Cells

(2016) Ah Ron Lee et al.   LIPIDS

Imaging of Proteins in Tissue Samples Using Nanospray Desorption Electrospray Ionization Mass Spectrometry

(2015) Cheng-Chih Hsu et al.   ANALYTICAL CHEMISTRY

Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias

(2015) M. R. Ricciardi et al.   BLOOD

Cancer-mediated adipose reversion promotes cancer cell migration via IL-6 and MCP-1

(2015) Kaoru Fujisaki et al.   BREAST CANCER RESEARCH AND TREATMENT

The acetyl-CoA carboxylase enzyme: a target for cancer therapy?

(2015) Chao Wang et al.   Expert Review of Anticancer Therapy

Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue

(2015) Gunisha Sagar et al.   GUT

Unsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of β-Catenin

(2015) Hyeonwoo Kim et al.   Cell Reports

Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia

(2014) E. Orgel et al.   BLOOD

Asparaginase-associated pancreatitis in children with acute lymphoblastic leukaemia in the NOPHO ALL2008 protocol

(2014) Raheel A. Raja et al.   BRITISH JOURNAL OF HAEMATOLOGY

Impact on Survival and Toxicity by Duration of Weight Extremes During Treatment for Pediatric Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group

(2014) Etan Orgel et al.   JOURNAL OF CLINICAL ONCOLOGY

A role for oleoylethanolamide in chronic lymphocytic leukemia

(2014) M Masoodi et al.   LEUKEMIA

Tumour-surrounding adipocytes are active players in breast cancer progression

(2013) Catherine Muller   ANNALES D ENDOCRINOLOGIE

Targeting Transmembrane TNF-α Suppresses Breast Cancer Growth

(2013) Mingxia Yu et al.   CANCER RESEARCH

Adipocytes Cause Leukemia Cell Resistance to L-Asparaginase via Release of Glutamine

(2013) E. A. Ehsanipour et al.   CANCER RESEARCH

Adipocyte differentiation is affected by media height above the cell layer

(2013) X Sheng et al.   INTERNATIONAL JOURNAL OF OBESITY

Adipose tissue attracts and protects acute lymphoblastic leukemia cells from chemotherapy

(2013) Rocky Pramanik et al.   LEUKEMIA RESEARCH

Microscopy ambient ionization top-down mass spectrometry reveals developmental patterning

(2013) C.-C. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SCD1 Inhibition Causes Cancer Cell Death by Depleting Mono-Unsaturated Fatty Acids

(2012) Paul Mason et al.   PLoS One

Inhibition of Fatty Acid Metabolism Reduces Human Myeloma Cells Proliferation

(2012) José Manuel Tirado-Vélez et al.   PLoS One

TNF inhibitor suppresses bone metastasis in a breast cancer cell line

(2011) Takahiko Hamaguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion

(2011) B. Dirat et al.   CANCER RESEARCH

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

(2011) Kristin M Nieman et al.   NATURE MEDICINE

Conservative treatment of L-asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia

(2010) Hofit Cohen et al.   PEDIATRIC BLOOD & CANCER

Diet-induced obesity alters vincristine pharmacokinetics in blood and tissues of mice

(2010) James W. Behan et al.   PHARMACOLOGICAL RESEARCH

Inhibition of Stearoyl-CoA Desaturase 1 Expression Induces CHOP-Dependent Cell Death in Human Cancer Cells

(2010) Mélaine Minville-Walz et al.   PLoS One

Adipocytes Impair Leukemia Treatment in Mice

(2009) J. W. Behan et al.   CANCER RESEARCH

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

(2009) Ismael Samudio et al.   JOURNAL OF CLINICAL INVESTIGATION