The Role of Platelet Cell Surface P-Selectin for the Direct Platelet-Tumor Cell Contact During Metastasis Formation in Human Tumors

Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX

(2020) Eudmar Marcolino et al.   Oncogenesis

Platelet-specific PDGFB ablation impairs tumor vessel integrity and promotes metastasis

(2020) Yanyu Zhang et al.   CANCER RESEARCH

Extravasated platelet aggregation contributes to tumor progression via the accumulation of myeloid‑derived suppressor cells in gastric cancer with peritoneal metastasis

(2020) Takahisa Yamaguchi et al.   Oncology Letters

Platelets and Metastasis: New Implications of an Old Interplay

(2020) Serena Lucotti et al.   Frontiers in Oncology

The functional role of integrins during intra- and extravasation within the metastatic cascade

(2019) Greta Sökeland et al.   Molecular Cancer

The History of Armand Trousseau and Cancer-Associated Thrombosis

(2019) Pat Metharom et al.   Cancers

Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2

(2019) Serena Lucotti et al.   JOURNAL OF CLINICAL INVESTIGATION

Gaps in the knowledge of human platelet lysate as a cell culture supplement for cell therapy: A joint publication from the AABB and the International Society of Cell Therapy

(2019) KAREN Bieback et al.   CYTOTHERAPY

Tumor-infiltrating platelets predict postoperative recurrence and survival in resectable pancreatic neuroendocrine tumor

(2019) Shuai-Shuai Xu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Platelet Signaling and Disease: Targeted Therapy for Thrombosis and Other Related Diseases

(2018) Jennifer Yeung et al.   PHARMACOLOGICAL REVIEWS

Tumor-Infiltrating Platelets Predict Postsurgical Survival in Patients with Pancreatic Ductal Adenocarcinoma

(2018) Shi-Rong Zhang et al.   ANNALS OF SURGICAL ONCOLOGY

Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes

(2018) Alexandra Soler et al.   Scientific Reports

Role of platelets and platelet receptors in cancer metastasis

(2018) Martin Schlesinger   Journal of Hematology & Oncology

EMT and MET: necessary or permissive for metastasis?

(2017) Mohit Kumar Jolly et al.   Molecular Oncology

Platelet microparticle-mediated transfer of miR-939 to epithelial ovarian cancer cells promotes epithelial to mesenchymal transition

(2017) Meiling Tang et al.   Oncotarget

Tumor cell intravasation

(2016) Serena P. H. Chiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The role of platelets in the tumor microenvironment: From solid tumors to leukemia

(2016) MengJie Yan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Metastasis: new functional implications of platelets and megakaryocytes

(2016) Raphael Leblanc et al.   BLOOD

Characteristics and Significance of the Pre-metastatic Niche

(2016) Yang Liu et al.   CANCER CELL

Melanoma cell metastasis via P-selectin-mediated activation of acid sphingomyelinase in platelets

(2016) Katrin Anne Becker et al.   CLINICAL & EXPERIMENTAL METASTASIS

Cancer Tills the Premetastatic Field: Mechanistic Basis and Clinical Implications

(2016) A. R. Chin et al.   CLINICAL CANCER RESEARCH

Platelets surrounding primary tumor cells are related to chemoresistance

(2016) Satoko Ishikawa et al.   ONCOLOGY REPORTS

Platelets Guide Leukocytes to Their Sites of Extravasation

(2016) Gabriele Zuchtriegel et al.   PLOS BIOLOGY

The role of EMT and MET in cancer dissemination

(2015) Jacqueline Banyard et al.   CONNECTIVE TISSUE RESEARCH

Culture of human cell lines by a pathogen-inactivated human platelet lysate

(2015) R. Fazzina et al.   CYTOTECHNOLOGY

An in vitro model of the tumor–lymphatic microenvironment with simultaneous transendothelial and luminal flows reveals mechanisms of flow enhanced invasion

(2015) M. Pisano et al.   Integrative Biology

Platelets in cancer metastasis: To help the “villain” to do evil

(2015) Nailin Li   INTERNATIONAL JOURNAL OF CANCER

Replacing the Promoter of the Murine Gene Encoding P-selectin with the Human Promoter Confers Human-like Basal and Inducible Expression in Mice

(2015) Zhenghui Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metastasis-promoting role of extravasated platelet activation in tumor

(2015) Tomoharu Miyashita et al.   JOURNAL OF SURGICAL RESEARCH

Regulation of the genetic code in megakaryocytes and platelets

(2015) M. T. Rondina et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

MicroRNA-223 delivered by platelet-derived microvesicles promotes lung cancer cell invasion via targeting tumor suppressor EPB41L3

(2015) Hongwei Liang et al.   Molecular Cancer

P-selectin-mediated platelet adhesion promotes tumor growth

(2015) Cuiling Qi et al.   Oncotarget

Platelet extracts induce growth, migration and invasion in human hepatocellular carcinoma in vitro

(2014) Brian I Carr et al.   BMC CANCER

Platelets and cancer: a casual or causal relationship: revisited

(2014) David G. Menter et al.   CANCER AND METASTASIS REVIEWS

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

(2014) Nicola Aceto et al.   CELL

The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

(2014) Sandra S. McAllister et al.   NATURE CELL BIOLOGY

P-Selectin-Mediated Platelet Adhesion Promotes the Metastasis of Murine Melanoma Cells

(2014) Cui-Ling Qi et al.   PLoS One

Platelets guide the formation of early metastatic niches

(2014) M. Labelle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet-Derived Nucleotides Promote Tumor-Cell Transendothelial Migration and Metastasis via P2Y2 Receptor

(2013) Dagmar Schumacher et al.   CANCER CELL

New paradigms in thrombosis: novel mediators and biomarkers platelet RNA transfer

(2013) Lauren Clancy et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Platelets increase the proliferation of ovarian cancer cells

(2012) M. S. Cho et al.   BLOOD

Platelets and platelet-like particles mediate intercellular RNA transfer

(2012) A. Risitano et al.   BLOOD

EMT and MET in Metastasis: Where Are the Cancer Stem Cells?

(2012) Thomas Brabletz   CANCER CELL

Selectin-deficiency reduces the number of spontaneous metastases in a xenograft model of human breast cancer

(2012) Katrin Stübke et al.   CANCER LETTERS

Platelets and P-Selectin Control Tumor Cell Metastasis in an Organ-Specific Manner and Independently of NK Cells

(2012) L. A. Coupland et al.   CANCER RESEARCH

Selectin binding is essential for peritoneal carcinomatosis in a xenograft model of human pancreatic adenocarcinoma in pfp−−/rag2−−mice

(2012) Florian Gebauer et al.   GUT

Modelling the lymphatic system: challenges and opportunities

(2012) K. N. Margaris et al.   Journal of the Royal Society Interface

The Initial Hours of Metastasis: The Importance of Cooperative Host-Tumor Cell Interactions during Hematogenous Dissemination

(2012) M. Labelle et al.   Cancer Discovery

Blood platelets contain tumor-derived RNA biomarkers

(2011) R. J. A. Nilsson et al.   BLOOD

Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli

(2011) M. Chatterjee et al.   BLOOD

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells

(2011) T. Placke et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Deadly allies: the fatal interplay between platelets and metastasizing cancer cells

(2010) L. Erpenbeck et al.   BLOOD

Antithrombotic therapy and survival in patients with malignant disease

(2010) A K Kakkar et al.   BRITISH JOURNAL OF CANCER

Differential regulation of human and murine P-selectin expression and function in vivo

(2010) Zhenghui Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microparticle-associated tissue factor activity and venous thrombosis in multiple myeloma

(2010) J. J. A. Auwerda et al.   THROMBOSIS AND HAEMOSTASIS

Antimetastatic activities of heparins and modified heparins. Experimental evidence

(2010) Lubor Borsig   THROMBOSIS RESEARCH

Modified heparins inhibit integrin αIIbβ3mediated adhesion of melanoma cells to plateletsin vitroandin vivo

(2009) ChunMei Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

Tissue factor-bearing microparticles derived from tumor cells: impact on coagulation activation

(2008) M. DAVILA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS