Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter

Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT

(2020) Renhong Yan et al.   Science Advances

Paternal Age and Transgenerational Telomere Length Maintenance: A Simulation Model

(2019) K. Horvath et al.   Scientific Reports

Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex

(2019) Renhong Yan et al.   NATURE

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

(2019) Yongchan Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effects of Mutations and Ligands on the Thermostability of the l-Arginine/Agmatine Antiporter AdiC and Deduced Insights into Ligand-Binding of Human l-Type Amino Acid Transporters

(2018) Hüseyin Ilgü et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structural basis for amino acid transport by the CAT family of SLC7 transporters

(2018) Katharina E. J. Jungnickel et al.   Nature Communications

The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health

(2018) Mariafrancesca Scalise et al.   Frontiers in Chemistry

Thyroid hormone transport across L-type amino acid transporters: What can molecular modelling tell us?

(2017) Gerd Krause et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

LAT-1 activity of meta -substituted phenylalanine and tyrosine analogs

(2016) Evan Augustyn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Selective and Slowly Reversible Inhibitor of l-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells

(2016) Kristiina M. Huttunen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Transport of gabapentin by LAT1 (SLC7A5)

(2013) David Dickens et al.   BIOCHEMICAL PHARMACOLOGY

Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1

(2013) E. G. Geier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

l-Type amino acid transporter 1 inhibitors inhibit tumor cell growth

(2009) Koji Oda et al.   CANCER SCIENCE

The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters

(2009) Lucy R. Forrest et al.   PHYSIOLOGY