Anti-Angiogenic Properties of Ginsenoside Rg3 Epimers: In Vitro Assessment of Single and Combination Treatments

Use of Antiangiogenic Therapies in Pediatric Solid Tumors

(2021) Claudia Ollauri-Ibáñez et al.   Cancers

Modulation of the Vascular-Immune Environment in Metastatic Cancer

(2021) Bo He et al.   Cancers

The Role of VEGF Receptors as Molecular Target in Nuclear Medicine for Cancer Diagnosis and Combination Therapy

(2021) Katarzyna Masłowska et al.   Cancers

Ginsenoside Rp1, A Ginsenoside Derivative, Augments Anti-Cancer Effects of Actinomycin D via Downregulation of an AKT-SIRT1 Pathway

(2020) Un-Jung Yun et al.   Cancers

Resistance Mechanisms to Anti-angiogenic Therapies in Cancer

(2020) Yolla Haibe et al.   Frontiers in Oncology

Anti-Angiogenic Properties of Ginsenoside Rg3

(2020) Maryam Nakhjavani et al.   MOLECULES

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy

(2019) Tian Tian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bumetanide-Derived Aquaporin 1 Inhibitors, AqB013 and AqB050 Inhibit Tube Formation of Endothelial Cells through Induction of Apoptosis and Impaired Migration In Vitro

(2019) Yoko Tomita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sending messages in moving cells: mRNA localization and the regulation of cell migration

(2019) Shane P. Herbert et al.   Essays in Biochemistry

Role of melatonin in controlling angiogenesis under physiological and pathological conditions

(2019) Qiang Ma et al.   ANGIOGENESIS

Molecular Targeting Therapy against EGFR Family in Breast Cancer: Progress and Future Potentials

(2019) Amaia Eleonora Maennling et al.   Cancers

Improved chemotherapeutic efficacy against resistant human breast cancer cells with co-delivery of Docetaxel and Thymoquinone by Chitosan grafted lipid nanocapsules: Formulation optimization, in vitro and in vivo studies

(2019) Sobiya Zafar et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Mangiferin-Loaded Polymeric Nanoparticles: Optical Characterization, Effect of Anti-topoisomerase I, and Cytotoxicity

(2019) Francisco Fabian Razura-Carmona et al.   Cancers

Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling

(2018) Katherine M. Thieltges et al.   ANGIOGENESIS

The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis

(2018) Helen Palethorpe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Advances in studies of tyrosine kinase inhibitors and their acquired resistance

(2018) Qinlian Jiao et al.   Molecular Cancer

Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma

(2018) Aurelia Lamanuzzi et al.   Oncotarget

Mechanisms of Aquaporin-Facilitated Cancer Invasion and Metastasis

(2018) Michael L. De Ieso et al.   Frontiers in Chemistry

The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis

(2018) Eric Smith et al.   Cells

The clinicopathological and prognostic value of hypoxia-inducible factor-2α in cancer patients: a systematic review and meta-analysis

(2018) Deqing Luo et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Role of Aquaporin 1 Signalling in Cancer Development and Progression

(2017) Yoko Tomita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways

(2017) Chunliu Mi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer

(2017) Meng-Chuan Chen et al.   Scientific Reports

Role of microRNA-520h in 20(R)-ginsenoside-Rg3-mediated angiosuppression

(2016) Man-Hong Keung et al.   Journal of Ginseng Research

The Clinical Importance of Assessing Tumor Hypoxia: Relationship of Tumor Hypoxia to Prognosis and Therapeutic Opportunities

(2014) Joseph C. Walsh et al.   ANTIOXIDANTS & REDOX SIGNALING

Stereospecificity of Ginsenoside Rg3 in the Promotion of Cellular Immunity in Hepatoma H22-Bearing Mice

(2014) Rihui Wu et al.   JOURNAL OF FOOD SCIENCE

mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3

(2014) K M Dodd et al.   ONCOGENE

Stereospecific effects of ginsenoside 20-Rg3 inhibits TGF-β1-induced epithelial–mesenchymal transition and suppresses lung cancer migration, invasion and anoikis resistance

(2014) Young-Joo Kim et al.   TOXICOLOGY

Use of Allosteric Targets in the Discovery of Safer Drugs

(2013) Ashok Kumar Grover   MEDICAL PRINCIPLES AND PRACTICE

α-santalol inhibits the angiogenesis and growth of human prostate tumor growth by targeting vascular endothelial growth factor receptor 2-mediated AKT/mTOR/P70S6K signaling pathway

(2013) Sarita Saraswati et al.   Molecular Cancer

Bevacizumab-induced serious side-effects: a review of the French pharmacovigilance database

(2012) Solène Taugourdeau-Raymond et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Overexpression of nuclear NHERF1 in advanced colorectal cancer: Association with hypoxic microenvironment and tumor invasive phenotype

(2012) Andrea Malfettone et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Stereospecific antioxidant effects of ginsenoside Rg3 on oxidative stress induced by cyclophosphamide in mice

(2012) Xiaojie Wei et al.   FITOTERAPIA

Stereospecificity of ginsenoside Rg3 in promotion of the immune response to ovalbumin in mice

(2012) X. Wei et al.   INTERNATIONAL IMMUNOLOGY

Inhibition of aquaporin-1 dependent angiogenesis impairs tumour growth in a mouse model of melanoma

(2012) Grazia P. Nicchia et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Drugs for Allosteric Sites on Receptors

(2011) Cody J. Wenthur et al.   Annual Review of Pharmacology and Toxicology

Translation initiation factors and active sites of protein synthesis co-localize at the leading edge of migrating fibroblasts

(2011) Mark Willett et al.   BIOCHEMICAL JOURNAL

Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization

(2011) M. S. Brozzo et al.   BLOOD

GSK-3 inactivation or depletion promotes β-cell replication via down regulation of the CDK inhibitor, p27 (Kip1)

(2011) Jeffrey Stein et al.   Islets

PI3K/AKT/mTOR Pathway in Angiogenesis

(2011) Jayashree Karar et al.   Frontiers in Molecular Neuroscience

Vascular endothelial growth factor and its relationship to the prognosis and treatment of breast, ovarian, and cervical cancer

(2010) Jennifer Delli Carpini et al.   ANGIOGENESIS

Aquaporins in tumor growth and angiogenesis

(2010) Beatrice Nico et al.   CANCER LETTERS

Tyrosine Kinase Inhibitors – A Review on Pharmacology, Metabolism and Side Effects

(2009) Jorg Hartmann et al.   CURRENT DRUG METABOLISM

Aquaporin 1 is required for hypoxia-inducible angiogenesis in human retinal vascular endothelial cells

(2008) Kentaro Kaneko et al.   MICROVASCULAR RESEARCH