GSK-3 inactivation or depletion promotes β-cell replication via down regulation of the CDK inhibitor, p27 (Kip1)

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

(2010) Nathalie M. Fiaschi-Taesch et al.   DIABETES

Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice

(2010) Y. Liu et al.   DIABETOLOGIA

Cdk4 Regulates Recruitment of Quiescent β-Cells and Ductal Epithelial Progenitors to Reconstitute β-Cell Mass

(2010) Ji-Hyeon Lee et al.   PLoS One

Survey of the Human Pancreatic  -Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D1 in Enhancing Human  -Cell Replication and Function In Vivo

(2009) N. Fiaschi-Taesch et al.   DIABETES

No mantle formation in rodent islets—The prototype of islet revisited

(2009) Michael Kharouta et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Deletion of the Mitochondrial Flavoprotein Apoptosis Inducing Factor (AIF) Induces β-Cell Apoptosis and Impairs β-Cell Mass

(2009) Fabienne T. Schulthess et al.   PLoS One

Glycogen Synthase Kinase-3 and Mammalian Target of Rapamycin Pathways Contribute to DNA Synthesis, Cell Cycle Progression, and Proliferation in Human Islets

(2008) H. Liu et al.   DIABETES

 -Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of  -Cell Mass in Humans

(2008) J. J. Meier et al.   DIABETES

Slow and steady is the key to β-cell replication

(2008) Kristen Brennand et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance

(2008) Katsuya Tanabe et al.   PLOS BIOLOGY