Mild traumatic brain injury induces microvascular injury and accelerates Alzheimer-like pathogenesis in mice

Blood–Brain Barrier Dysfunction in Mild Traumatic Brain Injury: Evidence From Preclinical Murine Models

(2020) Yingxi Wu et al.   Frontiers in Physiology

3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice

(2019) Divna Lazic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impairment of pericyte-endothelium crosstalk leads to blood-brain barrier dysfunction following traumatic brain injury

(2019) Saurav Bhowmick et al.   EXPERIMENTAL NEUROLOGY

Cerebral Microvascular Injury: A Potentially Treatable Endophenotype of Traumatic Brain Injury-Induced Neurodegeneration

(2019) Danielle K. Sandsmark et al.   NEURON

Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood–brain barrier dysfunction module

(2019) Roeben Nocon Munji et al.   NATURE NEUROSCIENCE

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

(2018) Chad A Tagge et al.   BRAIN

Risk of Dementia Outcomes Associated With Traumatic Brain Injury During Military Service

(2018) Kimbra Kenney et al.   JAMA Neurology

Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link

(2018) Jaime Ramos-Cejudo et al.   EBioMedicine

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

Molecular characterization of perivascular drainage pathways in the murine brain

(2017) Melanie-Jane Hannocks et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Traumatic Brain Injury Causes Endothelial Dysfunction in the Systemic Microcirculation through Arginase-1–Dependent Uncoupling of Endothelial Nitric Oxide Synthase

(2017) Nuria Villalba et al.   JOURNAL OF NEUROTRAUMA

The chronic and evolving neurological consequences of traumatic brain injury

(2017) Lindsay Wilson et al.   LANCET NEUROLOGY

Modulators of microglial activation and polarization after intracerebral haemorrhage

(2017) Xi Lan et al.   Nature Reviews Neurology

Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders

(2017) Qingying Meng et al.   EBioMedicine

Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling

(2017) Angeliki Maria Nikolakopoulou et al.   PLoS One

Traumatic brain injury results in acute rarefication of the vascular network

(2017) Andre Obenaus et al.   Scientific Reports

Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood–Brain Barrier Permeability following Experimental Traumatic Brain Injury

(2016) Pramod K. Dash et al.   JOURNAL OF NEUROSCIENCE

Amyloid pathology and axonal injury after brain trauma

(2016) Gregory Scott et al.   NEUROLOGY

Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition

(2016) Himakarnika Alluri et al.   PLoS One

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Ethyl Pyruvate Protects against Blood-Brain Barrier Damage and Improves Long-term Neurological Outcomes in a Rat Model of Traumatic Brain Injury

(2014) Hong Shi et al.   CNS Neuroscience & Therapeutics

Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity

(2014) Yao Yao et al.   Nature Communications

Traumatic Brain Injury as a Chronic Health Condition

(2013) John D. Corrigan et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

In vivo temporal and spatial profile of leukocyte adhesion and migration after experimental traumatic brain injury in mice

(2013) Susanne M Schwarzmaier et al.   Journal of Neuroinflammation

Repetitive Mild Traumatic Brain Injury Augments Tau Pathology and Glial Activation in Aged hTau Mice

(2013) Joseph-Olubunmi Ojo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Activated Protein C Analog Protects From Ischemic Stroke and Extends the Therapeutic Window of Tissue-Type Plasminogen Activator in Aged Female Mice and Hypertensive Rats

(2013) Yaoming Wang et al.   STROKE

Mri Assessment of Cerebral Blood Flow after Experimental Traumatic Brain Injury Combined with Hemorrhagic Shock in Mice

(2012) Lesley M Foley et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Early Brain Injury Alters the Blood–Brain Barrier Phenotype in Parallel with β-Amyloid and Cognitive Changes in Adulthood

(2012) Viorela Pop et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lithium Reduces BACE1 Overexpression, Beta Amyloid Accumulation, and Spatial Learning Deficits in Mice with Traumatic Brain Injury

(2012) Fengshan Yu et al.   JOURNAL OF NEUROTRAUMA

The Neuropathology and Neurobiology of Traumatic Brain Injury

(2012) Kaj Blennow et al.   NEURON

Twenty years of Alzheimer’s disease-causing mutations

(2011) Alison Goate et al.   JOURNAL OF NEUROCHEMISTRY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology