Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability

tRNA 2′-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila

(2020) Margarita T Angelova et al.   NUCLEIC ACIDS RESEARCH

Intellectual disability‐associated gene ftsj1 is responsible for 2′‐O‐methylation of specific tRNAs

(2020) Jing Li et al.   EMBO REPORTS

Complete chemical structures of human mitochondrial tRNAs

(2020) Takeo Suzuki et al.   Nature Communications

Matching tRNA modifications in humans to their known and predicted enzymes

(2019) Valérie de Crécy-Lagard et al.   NUCLEIC ACIDS RESEARCH

Cooperative 2′-O-methylation of the wobble cytidine of human elongator tRNAMet(CAT) by a nucleolar and a Cajal body-specific box C/D RNP

(2019) Patrice Vitali et al.   GENES & DEVELOPMENT

Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome

(2019) Christelle Arrondel et al.   Nature Communications

Biogenesis and functions of aminocarboxypropyluridine in tRNA

(2019) Mayuko Takakura et al.   Nature Communications

X-linked intellectual disability update 2017

(2018) Giovanni Neri et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

(2018) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor

(2018) Sydney P. Thomas et al.   RNA

Genome-wide Translation Profiling by Ribosome-Bound tRNA Capture

(2018) Chien-Wen Chen et al.   Cell Reports

Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway

(2018) Lu Han et al.   PLoS Genetics

PAK2 Haploinsufficiency Results in Synaptic Cytoskeleton Impairment and Autism-Related Behavior

(2018) Yan Wang et al.   Cell Reports

The emerging impact of tRNA modifications in the brain and nervous system

(2018) Jillian Ramos et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A mouse model for intellectual disability caused by mutations in the X-linked 2′‑O‑methyltransferase Ftsj1 gene

(2018) Lars R. Jensen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Transcriptome-wide Analysis of Roles for tRNA Modifications in Translational Regulation

(2017) Hsin-Jung Chou et al.   MOLECULAR CELL

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

RefEx, a reference gene expression dataset as a web tool for the functional analysis of genes

(2017) Hiromasa Ono et al.   Scientific Data

Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases

(2016) Sydney P. Thomas et al.   BIOCHEMISTRY

Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects

(2016) Fengping Dong et al.   HUMAN MOLECULAR GENETICS

Neural plasticity and behavior - sixty years of conceptual advances

(2016) J. David Sweatt   JOURNAL OF NEUROCHEMISTRY

RiboGalaxy: A browser based platform for the alignment, analysis and visualization of ribosome profiling data

(2016) Audrey M. Michel et al.   RNA Biology

ELP2is a novel gene implicated in neurodevelopmental disabilities

(2015) Julie S. Cohen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Defects in tRNA Anticodon Loop 2′-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations inFTSJ1

(2015) Michael P. Guy et al.   HUMAN MUTATION

From circuits to behaviour in the amygdala

(2015) Patricia H. Janak et al.   NATURE

Efficient and quantitative high-throughput tRNA sequencing

(2015) Guanqun Zheng et al.   NATURE METHODS

Genetic studies in intellectual disability and related disorders

(2015) Lisenka E. L. M. Vissers et al.   NATURE REVIEWS GENETICS

GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes

(2015) Patricia P. Chan et al.   NUCLEIC ACIDS RESEARCH

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

(2014) S. Blanco et al.   EMBO JOURNAL

De novo mutations in beta-catenin (CTNNB1) appear to be a frequent cause of intellectual disability: expanding the mutational and clinical spectrum

(2014) Alma Kuechler et al.   HUMAN GENETICS

Conservation of an intricate circuit for crucial modifications of the tRNAPheanticodon loop in eukaryotes

(2014) Michael P. Guy et al.   RNA

Striatal dopamine D1 receptor is essential for contextual fear conditioning

(2014) Masaru Ikegami et al.   Scientific Reports

Genetics of recessive cognitive disorders

(2013) Luciana Musante et al.   TRENDS IN GENETICS

Fragile X and X-Linked Intellectual Disability: Four Decades of Discovery

(2012) Herbert A. Lubs et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in NSUN2 Cause Autosomal- Recessive Intellectual Disability

(2012) Lia Abbasi-Moheb et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biosynthesis and Function of Posttranscriptional Modifications of Transfer RNAs

(2012) Basma El Yacoubi et al.   Annual Review of Genetics

Dendritic spines: from structure to in vivo function

(2012) Nathalie L Rochefort et al.   EMBO REPORTS

Synaptic scaffold evolution generated components of vertebrate cognitive complexity

(2012) Jess Nithianantharajah et al.   NATURE NEUROSCIENCE

The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments

(2012) Nicholas T Ingolia et al.   Nature Protocols

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis

(2012) Francesca Tuorto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop

(2012) M. P. Guy et al.   RNA

Severely Impaired Learning and Altered Neuronal Morphology in Mice Lacking NMDA Receptors in Medium Spiny Neurons

(2011) Lisa R. Beutler et al.   PLoS One

X-linked intellectual disability: Unique vulnerability of the male genome

(2009) Roger E. Stevenson et al.   Developmental Disabilities Research Reviews

Genetic Variations in FTSJ1 Influence Cognitive Ability in Young Males in the Chinese Han Population

(2008) Pingyuan Gong et al.   JOURNAL OF NEUROGENETICS

A loss-of-function mutation in theFTSJ1 gene causes nonsyndromic X-linked mental retardation in a japanese family

(2007) Kyoko Takano et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS