Single-Cell RNA Sequencing Reveals Tissue Compartment-Specific Plasticity of Mycosis Fungoides Tumor Cells

Developmental plasticity allows outside-in immune responses by resident memory T cells

(2020) Raissa Fonseca et al.   NATURE IMMUNOLOGY

A cell atlas of human thymic development defines T cell repertoire formation

(2020) Jong-Eun Park et al.   SCIENCE

Resident memory T cells show that it is never too late to change your ways

(2020) Iris K. Gratz et al.   NATURE IMMUNOLOGY

Update on Biology of Cutaneous T-Cell Lymphoma

(2020) Zaw H. Phyo et al.   Frontiers in Oncology

High-Dimensional T Helper Cell Profiling Reveals a Broad Diversity of Stably Committed Effector States and Uncovers Interlineage Relationships

(2020) Luigi Tortola et al.   IMMUNITY

Branched evolution and genomic intratumor heterogeneity in the pathogenesis of cutaneous T-cell lymphoma

(2020) Aishwarya Iyer et al.   Blood Advances

The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas

(2019) Rein Willemze et al.   BLOOD

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Single-cell profiling of cutaneous T-cell lymphoma reveals underlying heterogeneity associated with disease progression

(2019) Nicholas Borcherding et al.   CLINICAL CANCER RESEARCH

Tissue-Resident T Cells and Other Resident Leukocytes

(2019) David Masopust et al.   Annual Review of Immunology

Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors

(2019) Alyxzandria M. Gaydosik et al.   CLINICAL CANCER RESEARCH

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma

(2019) Jared M. Andrews et al.   EBioMedicine

Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals

(2019) Maria M. Klicznik et al.   Science Immunology

Location, location, location: Tissue resident memory T cells in mice and humans

(2019) Peter A. Szabo et al.   Science Immunology

Targeting CD47 as a cancer therapeutic strategy

(2018) Alecia S. Folkes et al.   CURRENT OPINION IN ONCOLOGY

Linking transcriptional and genetic tumor heterogeneity through allele analysis of single-cell RNA-seq data

(2018) Jean Fan et al.   GENOME RESEARCH

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Primary T cells from cutaneous T-cell lymphoma skin explants display an exhausted immune checkpoint profile

(2018) Christiane Querfeld et al.   Cancer Immunology Research

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas

(2017) Pilvi Maliniemi et al.   OncoImmunology

Localized signals that regulate transendothelial migration

(2016) William A Muller   CURRENT OPINION IN IMMUNOLOGY

TIGIT Enhances Antigen-Specific Th2 Recall Responses and Allergic Disease

(2016) Evangelia Kourepini et al.   JOURNAL OF IMMUNOLOGY

Imprinting of Skin/Inflammation Homing in CD4+T Cells Is Controlled by DNA Methylation within theFucosyltransferase 7Gene

(2016) Matthias Pink et al.   JOURNAL OF IMMUNOLOGY

TOX expression and role in CTCL

(2016) L.Y. McGirt et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Malignant inflammation in cutaneous T‐cell lymphoma—a hostile takeover

(2016) Thorbjørn Krejsgaard et al.   Seminars in Immunopathology

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

(2016) Nicholas Collins et al.   Nature Communications

Mechanism, Consequences, and Therapeutic Targeting of Abnormal IL15 Signaling in Cutaneous T-cell Lymphoma

(2016) A. Mishra et al.   Cancer Discovery

The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome

(2015) Ana Carolina da Silva Almeida et al.   NATURE GENETICS

Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma

(2015) Takeya Adachi et al.   NATURE MEDICINE

TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL

(2015) Ilan R. Kirsch et al.   Science Translational Medicine

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

(2015) Rei Watanabe et al.   Science Translational Medicine

Resident memory T cells in human health and disease

(2015) R. A. Clark   Science Translational Medicine

Deregulation in STAT signaling is important for cutaneous T-cell lymphoma (CTCL) pathogenesis and cancer progression

(2014) Elena Netchiporouk et al.   CELL CYCLE

Depletion of M2-Like Tumor-Associated Macrophages Delays Cutaneous T-Cell Lymphoma Development In Vivo

(2014) Xuesong Wu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome)

(2014) Sarah I. Jawed et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma

(2013) Katharina Kopp et al.   CELL CYCLE

TH2 Cytokines from Malignant Cells Suppress TH1 Responses and Enforce a Global TH2 Bias in Leukemic Cutaneous T-cell Lymphoma

(2013) E. Guenova et al.   CLINICAL CANCER RESEARCH

Silencing α1,3-Fucosyltransferases in Human Leukocytes Reveals a Role for FUT9 Enzyme during E-selectin-mediated Cell Adhesion

(2012) Alexander Buffone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of the numbers of CD163+ cells in lesional skin and serum levels of soluble CD163 with disease progression of cutaneous T cell lymphoma

(2012) Makoto Sugaya et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations

(2011) Pejman Soroosh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nonsteroidal Anti-Inflammatory Drugs Induce Apoptosis in Cutaneous T-Cell Lymphoma Cells and Enhance Their Sensitivity for TNF-Related Apoptosis-Inducing Ligand

(2011) Frank K. Braun et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Deep Sequencing of the Human TCR  and TCR  Repertoires Suggests that TCR  Rearranges After    and    T Cell Commitment

(2011) A. M. Sherwood et al.   Science Translational Medicine

Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors

(2010) J. J. Campbell et al.   BLOOD

Aire and T cell development

(2010) Mark S Anderson et al.   CURRENT OPINION IN IMMUNOLOGY

Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells

(2009) R. A. Wilcox et al.   BLOOD

Inducible Costimulator Expression Regulates the Magnitude of Th2-Mediated Airway Inflammation by Regulating the Number of Th2 Cells

(2009) Bryan S. Clay et al.   PLoS One

Fucosyltransferase VII-positive, skin-homing T cells in the blood and skin lesions of atopic dermatitis patients

(2008) Yoshiko Mizukawa et al.   EXPERIMENTAL DERMATOLOGY

Serum levels of Th2 chemokines, CCL17, CCL22, and CCL27, were the important markers of severity in infantile atopic dermatitis

(2008) Junko Nakazato et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY