One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2

SOX2 protein transduction directly converts human fibroblasts into oligodendrocyte-like cells

(2020) Alireza Pouya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Altered human oligodendrocyte heterogeneity in multiple sclerosis

(2019) Sarah Jäkel et al.   NATURE

Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons

(2019) Joseph Herdy et al.   eLife

Reprogramming of Fibroblasts to Oligodendrocyte Progenitor-like Cells Using CRISPR/Cas9-Based Synthetic Transcription Factors

(2019) Mantas Matjusaitis et al.   Stem Cell Reports

SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells

(2018) Juan Antonio García-León et al.   Stem Cell Reports

Sequentially acting SOX proteins orchestrate astrocyte‐ and oligodendrocyte‐specific gene expression

(2018) Susanne Klum et al.   EMBO REPORTS

Induction of myelinating oligodendrocytes in human cortical spheroids

(2018) Mayur Madhavan et al.   NATURE METHODS

Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium

(2018) Bernt Popp et al.   Scientific Reports

Achievements and obstacles of remyelinating therapies in multiple sclerosis

(2017) Martin Stangel et al.   Nature Reviews Neurology

Axo-myelinic neurotransmission: a novel mode of cell signalling in the central nervous system

(2017) I. Micu et al.   NATURE REVIEWS NEUROSCIENCE

Regenerating CNS myelin — from mechanisms to experimental medicines

(2017) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors

(2017) Marc Ehrlich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts

(2016) Christine J Huh et al.   eLife

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

(2015) Jerome Mertens et al.   Cell Stem Cell

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

Generation and isolation of oligodendrocyte progenitor cells from human pluripotent stem cells

(2015) Panagiotis Douvaras et al.   Nature Protocols

Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived Oligodendrocytes

(2014) Yuko Numasawa-Kuroiwa et al.   Stem Cell Reports

Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes

(2013) S. A. Hoffmann et al.   DEVELOPMENT

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

Generation of oligodendroglial cells by direct lineage conversion

(2013) Nan Yang et al.   NATURE BIOTECHNOLOGY

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

(2013) Fadi J Najm et al.   NATURE BIOTECHNOLOGY

Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS

(2013) K. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state

(2011) L. Lapasset et al.   GENES & DEVELOPMENT

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Genome-scale DNA methylation maps of pluripotent and differentiated cells

(2008) Alexander Meissner et al.   NATURE