Recent Developments in Ion-Sensitive Systems for Pharmaceutical Applications

Targeted drug delivery strategies for precision medicines

(2021) Mandana T. Manzari et al.   Nature Reviews Materials

Combination of Nanomicellar Technology and In Situ Gelling Polymer as Ocular Drug Delivery System (ODDS) for Cyclosporine-A

(2021) Eleonora Terreni et al.   Pharmaceutics

Primary Studies on Construction and Evaluation of Ion-Sensitive in situ Gel Loaded with Paeonol-Solid Lipid Nanoparticles for Intranasal Drug Delivery

(2020) Yue Sun et al.   International Journal of Nanomedicine

Extracellular Ion-Responsive Logic Sensors Utilizing DNA Dimeric Nanoassemblies on Cell Surface and Application to Boosting AS1411 Internalization

(2020) Pai Peng et al.   ANALYTICAL CHEMISTRY

Doubly crosslinked biodegradable hydrogels based on gellan gum and chitosan for drug delivery and wound dressing

(2020) Xiaomin Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

(2020) Junjie Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Calcium Buffering in the Heart in Health and Disease

(2019) Godfrey L. Smith et al.   CIRCULATION

Construction and in vivo/in vitro evaluation of a nanoporous ion-responsive targeted drug delivery system for recombinant human interferon α-2b delivery

(2019) Hongfei Liu et al.   International Journal of Nanomedicine

A review on heavy metal pollution, toxicity and remedial measures: Current trends and future perspectives

(2019) Kilaru Harsha Vardhan et al.   JOURNAL OF MOLECULAR LIQUIDS

Smart polymer-based calcium-ion self-regulated nanochannels by mimicking the biological Ca2+-induced Ca2+ release process

(2019) Yunlong Li et al.   NPG Asia Materials

Electrospun nanofibers – A promising solid in-situ gelling alternative for ocular drug delivery

(2019) Benedikt Göttel et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Influence of Ionic Strength on the pH-sensitive in vitro Ibuprofen Release from Dextran-poly(acrylic acid) Copolymer

(2018) Yanna Zheng et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Recent trends on gellan gum blends with natural and synthetic polymers: A review

(2018) Khalid Mahmood Zia et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Dual-responsive lidocaine in situ gel reduces pain of intrauterine device insertion

(2018) Noura H. Abd Ellah et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A novel ocular delivery of brinzolamide based on gellan gum: in vitro and in vivo evaluation

(2018) Jingfen Sun et al.   Drug Design Development and Therapy

Ion-sensitive in situ hydrogels of natamycin bilosomes for enhanced and prolonged ocular pharmacotherapy: in vitro permeability, cytotoxicity and in vivo evaluation

(2018) Karthik Yadav Janga et al.   Artificial Cells Nanomedicine and Biotechnology

IN-SITU GEL FORMULATION FOR ENHANCED OCULAR DELIVERY OF NEPAFENAC

(2018) Haley Shelley et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Inner layer-embedded contact lenses for ion-triggered controlled drug delivery

(2018) Qiang Zhu et al.   Materials Science & Engineering C-Materials for Biological Applications

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

(2018) Stella Gänger et al.   Pharmaceutics

Zinc Signal in Brain Diseases

(2017) Stuart Portbury et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intracellular Ca 2+ Sensing: Its Role in Calcium Homeostasis and Signaling

(2017) Rafaela Bagur et al.   MOLECULAR CELL

Smart Macroporous IPN Hydrogels Responsive to pH, Temperature, and Ionic Strength: Synthesis, Characterization, and Evaluation of Controlled Release of Drugs

(2016) Ecaterina Stela Dragan et al.   ACS Applied Materials & Interfaces

An Optical Sensor Based on a Photonic Polymer Film to Detect Calcium in Serum

(2016) Monali Moirangthem et al.   ADVANCED FUNCTIONAL MATERIALS

Structural Characterization of Sodium Alginate and Calcium Alginate

(2016) Hadas Hecht et al.   BIOMACROMOLECULES

Fabrication of an ionic-sensitive in situ gel loaded with resveratrol nanosuspensions intended for direct nose-to-brain delivery

(2016) Jifu Hao et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Circulating calcium concentrations, vascular disease and mortality: a systematic review

(2016) I. R. Reid et al.   JOURNAL OF INTERNAL MEDICINE

Avidin–biotin capped mesoporous silica nanoparticles as an ion-responsive release system to determine lead(II)

(2015) Weiling Song et al.   ANALYTICAL BIOCHEMISTRY

An in situ gelling system for bone regeneration of osteochondral defects

(2015) Davide Bellini et al.   EUROPEAN POLYMER JOURNAL

Synthesis of pH- and ionic strength-responsive microgels and their interactions with lysozyme

(2015) Bao Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Liposome incorporated ion sensitive in situ gels for opthalmic delivery of timolol maleate

(2015) Shihui Yu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Zn2+-Triggered Drug Release from Biocompatible Zirconium MOFs Equipped with Supramolecular Gates

(2015) Li-Li Tan et al.   Small

Cancer as a channelopathy: ion channels and pumps in tumor development and progression

(2015) Alisa Litan et al.   Frontiers in Cellular Neuroscience

Bispidinone-based molecular switches for construction of stimulus-sensitive liposomal containers

(2014) Polina N. Veremeeva et al.   TETRAHEDRON

A metal–ion-responsive adhesive material via switching of molecular recognition properties

(2014) Takashi Nakamura et al.   Nature Communications

Smart polymers for the controlled delivery of drugs – a concise overview

(2014) Honey Priya James et al.   Acta Pharmaceutica Sinica B

Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo

(2013) E. Deu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preparation and characterization of rifampicin-PLGA microspheres/sodium alginate in situ gel combination delivery system

(2012) Chunhui Hu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Development ofin vitromodels to demonstrate the ability of PecSys®, anin situnasal gelling technology, to reduce nasal run-off and drip

(2012) Jonathan Castile et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Formulation and evaluation of microemulsion-basedin situion-sensitive gelling systems for intranasal administration of curcumin

(2012) Shuang Wang et al.   JOURNAL OF DRUG TARGETING

Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting

(2011) M. Murakami et al.   Science Translational Medicine

Inorganic Mercury Detection and Controlled Release of Chelating Agents from Ion-Responsive Liposomes

(2009) Mehmet Veysel Yigit et al.   CHEMISTRY & BIOLOGY

Formulation and evaluation ofin situgels containing clotrimazole for oral candidiasis

(2009) NM Harish et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Cation-Triggered Drug Release from a Porous Zinc−Adeninate Metal−Organic Framework

(2009) Jihyun An et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formulation and evaluation of in situ gelling system of dimenhydrinate for nasal administration

(2009) Veena S. Belgamwar et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors

(2008) Yuki Hori et al.   Acta Biomaterialia

In situ gel based on gellan gum as new carrier for nasal administration of mometasone furoate

(2008) S CAO et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS