Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi

Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline

(2021) Oriana Villafraz et al.   PLoS Pathogens

Structure, Properties, and Function of Glycosomes in Trypanosoma cruzi

(2020) Wilfredo Quiñones et al.   Frontiers in Cellular and Infection Microbiology

The Influence of Environmental Cues on the Development of Trypanosoma cruzi in Triatominae Vector

(2020) Raíssa de Fátima Pimentel Melo et al.   Frontiers in Cellular and Infection Microbiology

Trypanosoma cruzi synthesizes proline via a Δ1-pyrroline-5-carboxylate reductase whose activity is fine-tuned by NADPH cytosolic pools

(2020) Letícia Marchese et al.   BIOCHEMICAL JOURNAL

Proteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes

(2019) Héctor Acosta et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis

(2018) Ajit S. Divakaruni et al.   Cell Metabolism

Chagas disease

(2018) José A Pérez-Molina et al.   LANCET

Trypanosoma cruzi epimastigotes store cholesteryl esters in lipid droplets after cholesterol endocytosis

(2018) Miria G. Pereira et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

L-Glutamine uptake is developmentally regulated and is involved in metacyclogenesis in Trypanosoma cruzi

(2018) Flávia S. Damasceno et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Lipid metabolism in insect disease vectors

(2018) Katia C. Gondim et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Metabolomic profiling reveals a finely tuned, starvation-induced metabolic switch inTrypanosoma cruziepimastigotes

(2017) María Julia Barisón et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The active transport of histidine and its role in ATP production in Trypanosoma cruzi

(2016) M. J. Barisón et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Peroxisomes in parasitic protists

(2016) Toni Gabaldón et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection

(2016) Yuan Li et al.   PLoS Pathogens

Role of Δ1-Pyrroline-5-Carboxylate Dehydrogenase Supports Mitochondrial Metabolism and Host-Cell Invasion ofTrypanosoma cruzi

(2015) Brian S. Mantilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chagas’ Disease

(2015) Caryn Bern   NEW ENGLAND JOURNAL OF MEDICINE

Trypanosoma cruzi Epimastigotes Are Able to Manage Internal Cholesterol Levels under Nutritional Lipid Stress Conditions

(2015) Miria Gomes Pereira et al.   PLoS One

Perimicrovillar membrane assembly: the fate of phospholipids synthesised by the midgut of Rhodnius prolixus

(2014) Paula Rego Bittencourt-Cunha et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei

(2014) Stefan Allmann et al.   PLoS One

Memantine, an Antagonist of the NMDA Glutamate Receptor, Affects Cell Proliferation, Differentiation and the Intracellular Cycle and Induces Apoptosis in Trypanosoma cruzi

(2014) Flávia Silva Damasceno et al.   PLoS Neglected Tropical Diseases

An Insight into the Transcriptome of the Digestive Tract of the Bloodsucking Bug, Rhodnius prolixus

(2014) José M. C. Ribeiro et al.   PLoS Neglected Tropical Diseases

Proline Dehydrogenase Regulates Redox State and Respiratory Metabolism in Trypanosoma cruzi

(2013) Lisvane Silva Paes et al.   PLoS One

Metabolic Signatures of Triatomine Vectors of Trypanosoma cruzi Unveiled by Metabolomics

(2013) Luis Caetano M. Antunes et al.   PLoS One

Channel-Forming Activities in the Glycosomal Fraction from the Bloodstream Form of Trypanosoma brucei

(2012) Melisa Gualdron-López et al.   PLoS One

The Uniqueness of the Trypanosoma cruzi Mitochondrion: Opportunities to Target New Drugs Against Chagas Disease

(2011) Lisvane Silva Paes et al.   CURRENT PHARMACEUTICAL DESIGN

When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle

(2011) Melisa Gualdrón-López et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Comparative studies on the biochemical properties of  the malic enzymes from Trypanosoma cruzi and Trypanosoma brucei

(2010) Alejandro E. Leroux et al.   FEMS MICROBIOLOGY LETTERS

Synthesis and mobilization of glycogen and trehalose in adult maleRhodnius prolixus

(2009) Ana C. Mariano et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

An improved method to determine serine palmitoyltransferase activity

(2009) Markus F. Rütti et al.   JOURNAL OF LIPID RESEARCH

Actions of a Proline Analogue, L-Thiazolidine-4-Carboxylic Acid (T4C), on Trypanosoma cruzi

(2009) Anahí Magdaleno et al.   PLoS One

Biochemical characterization of stage-specific isoforms of aspartate aminotransferases from Trypanosoma cruzi and Trypanosoma brucei

(2008) Daniela Marciano et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY