Reactive astrocytes facilitate vascular repair and remodeling after stroke

Brain capillary pericytes exert a substantial but slow influence on blood flow

(2021) David A. Hartmann et al.   NATURE NEUROSCIENCE

Improved tools to study astrocytes

(2020) Xinzhu Yu et al.   NATURE REVIEWS NEUROSCIENCE

Acute Ablation of Cortical Pericytes Leads to Rapid Neurovascular Uncoupling

(2020) Kassandra Kisler et al.   Frontiers in Cellular Neuroscience

Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling

(2020) Jana Gӧbel et al.   Cell Metabolism

Basement Membrane Changes in Ischemic Stroke

(2020) Minkyung Kang et al.   STROKE

Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes

(2020) Fei He et al.   Science Advances

Decoding the Transcriptional Response to Ischemic Stroke in Young and Aged Mouse Brain

(2020) Peter Androvic et al.   Cell Reports

Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury

(2020) Kevin A. Guttenplan et al.   Cell Reports

Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury

(2020) Ana L. Vivinetto et al.   Cell Reports

Structural and Functional Remodeling of the Brain Vasculature Following Stroke

(2020) Moises Freitas-Andrade et al.   Frontiers in Physiology

Astrocytes are necessary for blood–brain barrier maintenance in the adult mouse brain

(2020) Benjamin P. Heithoff et al.   GLIA

A Window of Vascular Plasticity Coupled to Behavioral Recovery after Stroke

(2020) Michael R. Williamson et al.   JOURNAL OF NEUROSCIENCE

Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity

(2020) Michael V. Sofroniew   TRENDS IN IMMUNOLOGY

Astrocytic endfeet re-cover blood vessels after removal by laser ablation

(2019) Hideaki Kubotera et al.   Scientific Reports

Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments

(2019) Taylor A. Clark et al.   Scientific Reports

Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury

(2019) Jarred M. Griffin et al.   GENE THERAPY

Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke

(2019) Ruslan Rust et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Refueling the Ischemic CNS: Guidance Molecules for Vascular Repair

(2019) Ruslan Rust et al.   TRENDS IN NEUROSCIENCES

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Rehabilitative training interacts with ischemia-instigated spine dynamics to promote a lasting population of new synapses in peri-infarct motor cortex

(2019) Taylor A. Clark et al.   JOURNAL OF NEUROSCIENCE

Combined Rehabilitation Promotes the Recovery of Structural and Functional Features of Healthy Neuronal Networks after Stroke

(2019) Anna Letizia Allegra Mascaro et al.   Cell Reports

Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood–brain barrier dysfunction module

(2019) Roeben Nocon Munji et al.   NATURE NEUROSCIENCE

Functions of subventricular zone neural precursor cells in stroke recovery

(2019) Michael R. Williamson et al.   BEHAVIOURAL BRAIN RESEARCH

Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines

(2019) Neng-Yuan Hu et al.   Neuroscience Bulletin

Anti-Nogo-A antibodies prevent vascular leakage and act as pro-angiogenic factors following stroke

(2019) Ruslan Rust et al.   Scientific Reports

Normal aging induces A1-like astrocyte reactivity

(2018) Laura E. Clarke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compromised microvascular oxygen delivery increases brain tissue vulnerability with age

(2018) Mohammad Moeini et al.   Scientific Reports

The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain

(2018) Matthew M. Boisvert et al.   Cell Reports

Contributions of the glycocalyx, endothelium, and extravascular compartment to the blood–brain barrier

(2018) Nikolay Kutuzov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basement membrane and blood–brain barrier

(2018) Lingling Xu et al.   JOURNAL OF INVESTIGATIVE MEDICINE

The vascular basement membrane in the healthy and pathological brain

(2017) Maj S Thomsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Functional deficits induced by cortical microinfarcts

(2017) Philipp M Summers et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Coordinated plasticity of synapses and astrocytes underlies practice-driven functional vicariation in peri-infarct motor cortex

(2017) Soo Young Kim et al.   JOURNAL OF NEUROSCIENCE

A Critical Role for Astrocytes in Hypercapnic Vasodilation in Brain

(2017) Clare Howarth et al.   JOURNAL OF NEUROSCIENCE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

The Indispensable Roles of Microglia and Astrocytes during Brain Development

(2016) Kitty Reemst et al.   Frontiers in Human Neuroscience

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles

(2016) Anusha Mishra et al.   NATURE NEUROSCIENCE

Astrocyte Depletion Impairs Redox Homeostasis and Triggers Neuronal Loss in the Adult CNS

(2015) Bettina Schreiner et al.   Cell Reports

Characterization of the role of adult neurogenesis in touch-screen discrimination learning

(2014) Alicia A. Swan et al.   HIPPOCAMPUS

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

Transcriptomics of Post-Stroke Angiogenesis in the Aged Brain

(2014) Ana Maria Buga et al.   Frontiers in Aging Neuroscience

Sexually Dimorphic Neurons in the Ventromedial Hypothalamus Govern Mating in Both Sexes and Aggression in Males

(2013) Cindy F. Yang et al.   CELL

Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Valery L Feigin et al.   LANCET

Nogo-A is a negative regulator of CNS angiogenesis

(2013) T. Walchli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The perineuronal net and the control of CNS plasticity

(2012) Difei Wang et al.   CELL AND TISSUE RESEARCH

The glycocalyx is present as soon as blood flow is initiated and is required for normal vascular development

(2012) Caitlin E. Henderson-Toth et al.   DEVELOPMENTAL BIOLOGY

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery

(2012) K. Hayakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet

(2011) N. N. Haj-Yasein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Organization of the Forelimb Representation of the C57BL/6 Mouse Motor Cortex as Defined by Intracortical Microstimulation and Cytoarchitecture

(2010) Kelly A. Tennant et al.   CEREBRAL CORTEX

The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction

(2010) Thomas Misje Mathiisen et al.   GLIA

Inhibition of Reactive Astrocytes with Fluorocitrate Retards Neurovascular Remodeling and Recovery after Focal Cerebral Ischemia in Mice

(2010) Kazuhide Hayakawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Local Hemodynamics Dictate Long-Term Dendritic Plasticity in Peri-Infarct Cortex

(2010) R. Mostany et al.   JOURNAL OF NEUROSCIENCE

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

(2010) Pavel I Ortinski et al.   NATURE NEUROSCIENCE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON