Neural circuits and activity dynamics underlying sex-specific effects of chronic social isolation stress

Prefrontal Cortex Corticotropin-Releasing Factor Neurons Control Behavioral Style Selection under Challenging Situations

(2020) Peng Chen et al.   NEURON

DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats

(2020) Puneet K. Sharma et al.   Neurotherapeutics

Interacting neural ensembles in orbitofrontal cortex for social and feeding behaviour

(2019) Joshua H. Jennings et al.   NATURE

HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors

(2019) Jia Cheng et al.   NEURON

A Disinhibitory Microcircuit Mediates Conditioned Social Fear in the Prefrontal Cortex

(2019) Haifeng Xu et al.   NEURON

Divergent medial amygdala projections regulate approach–avoidance conflict behavior

(2019) Samara M. Miller et al.   NATURE NEUROSCIENCE

Animal models of (or for) aggression reward, addiction, and relapse: behavior and circuits

(2019) Sam A. Golden et al.   JOURNAL OF NEUROSCIENCE

The molecular and cellular mechanisms of depression: a focus on reward circuitry

(2019) Megan E. Fox et al.   MOLECULAR PSYCHIATRY

Long-Term Behavioral Effects of Post-weaning Social Isolation in Males and Females

(2019) Deena M. Walker et al.   Frontiers in Behavioral Neuroscience

Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

(2019) Catherine Jensen Peña et al.   Nature Communications

Directional hippocampal-prefrontal interactions during working memory

(2018) Tiaotiao Liu et al.   BEHAVIOURAL BRAIN RESEARCH

The Multifaceted Role of the Ventromedial Prefrontal Cortex in Emotion, Decision Making, Social Cognition, and Psychopathology

(2018) Jaryd Hiser et al.   BIOLOGICAL PSYCHIATRY

The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress

(2018) Moriel Zelikowsky et al.   CELL

Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome

(2018) Wei Wang et al.   JOURNAL OF NEUROSCIENCE

Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition

(2018) Luye Qin et al.   NATURE NEUROSCIENCE

Peripubertal stress-induced heightened aggression: modulation of the glucocorticoid receptor in the central amygdala and normalization by mifepristone treatment

(2018) Aurelie Papilloud et al.   NEUROPSYCHOPHARMACOLOGY

Active avoidance requires inhibitory signaling in the rodent prelimbic prefrontal cortex

(2018) Maria M Diehl et al.   eLife

HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress

(2018) Peng Zhong et al.   eLife

Recent advances in the study of aggression

(2018) Meghan E. Flanigan et al.   NEUROPSYCHOPHARMACOLOGY

Neural circuits for a top-down control of fear and extinction

(2018) Roger Marek et al.   PSYCHOPHARMACOLOGY

Sex Differences in Risk and Resilience: Stress Effects on the Neural Substrates of Emotion and Motivation

(2018) Cara L. Wellman et al.   JOURNAL OF NEUROSCIENCE

Stress Exposure in Dopamine D4 Receptor Knockout Mice Induces Schizophrenia-Like Behaviors via Disruption of GABAergic Transmission

(2018) Tao Tan et al.   SCHIZOPHRENIA BULLETIN

Population coding of valence in the basolateral amygdala

(2018) Xian Zhang et al.   Nature Communications

What is play fighting and what is it good for?

(2017) Sergio M. Pellis et al.   LEARNING & BEHAVIOR

Sex-specific transcriptional signatures in human depression

(2017) Benoit Labonté et al.   NATURE MEDICINE

Esr1+ cells in the ventromedial hypothalamus control female aggression

(2017) Koichi Hashikawa et al.   NATURE NEUROSCIENCE

Motivational neural circuits underlying reinforcement learning

(2017) Bruno B Averbeck et al.   NATURE NEUROSCIENCE

Disrupted Glutamatergic Transmission in Prefrontal Cortex Contributes to Behavioral Abnormality in an Animal Model of ADHD

(2017) Jia Cheng et al.   NEUROPSYCHOPHARMACOLOGY

Impact of adolescent social experiences on behavior and neural circuits implicated in mental illnesses

(2017) Andrew R. Burke et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

History of winning remodels thalamo-PFC circuit to reinforce social dominance

(2017) Tingting Zhou et al.   SCIENCE

Prefrontal Cortex Drives Distinct Projection Neurons in the Basolateral Amygdala

(2017) Laura M. McGarry et al.   Cell Reports

Neural activity in the prelimbic and infralimbic cortices of freely moving rats during social interaction: Effect of isolation rearing

(2017) Chihiro Minami et al.   PLoS One

Sex-specific effects of early life stress on social interaction and prefrontal cortex dendritic morphology in young rats

(2016) M.R. Farrell et al.   BEHAVIOURAL BRAIN RESEARCH

The neural circuits of mating and fighting in male mice

(2016) Koichi Hashikawa et al.   CURRENT OPINION IN NEUROBIOLOGY

Enhanced Neuronal Activity in the Medial Prefrontal Cortex during Social Approach Behavior

(2016) E. Lee et al.   JOURNAL OF NEUROSCIENCE

Amygdala hyperactivation to angry faces in intermittent explosive disorder

(2016) Michael S. McCloskey et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Developmental timing and critical windows for the treatment of psychiatric disorders

(2016) Oscar Marín   NATURE MEDICINE

Hypothalamic control of male aggression-seeking behavior

(2016) Annegret L Falkner et al.   NATURE NEUROSCIENCE

SHANK3 controls maturation of social reward circuits in the VTA

(2016) Sebastiano Bariselli et al.   NATURE NEUROSCIENCE

DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

(2016) Patrick Aldrin-Kirk et al.   NEURON

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

The neurobiology of aggression and violence

(2015) Daniel R. Rosell et al.   CNS SPECTRUMS

Effects of social defeat on dopamine neurons in the ventral tegmental area in male and female California mice

(2015) Gian D. Greenberg et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress

(2015) G. E. Hodes et al.   JOURNAL OF NEUROSCIENCE

Sex differences and stress across the lifespan

(2015) Tracy L Bale et al.   NATURE NEUROSCIENCE

Stress Effects on Neuronal Structure: Hippocampus, Amygdala and Prefrontal Cortex

(2015) Bruce S McEwen et al.   NEUROPSYCHOPHARMACOLOGY

Mapping Social Behavior-Induced Brain Activation at Cellular Resolution in the Mouse

(2015) Yongsoo Kim et al.   Cell Reports

Antagonistic Control of Social versus Repetitive Self-Grooming Behaviors by Separable Amygdala Neuronal Subsets

(2014) Weizhe Hong et al.   CELL

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

Functional Connectivity in a Rat Model of Alzheimer's Disease During a Working Memory Task

(2014) Tiaotiao Liu et al.   Current Alzheimer Research

Effects of Adverse Early-Life Events on Aggression and Anti-Social Behaviours in Animals and Humans

(2014) J. Haller et al.   JOURNAL OF NEUROENDOCRINOLOGY

Pathway-Selective Adjustment of Prefrontal-Amygdala Transmission during Fear Encoding

(2014) M. Arruda-Carvalho et al.   JOURNAL OF NEUROSCIENCE

The organization of the stress system and its dysregulation in depressive illness

(2014) P W Gold   MOLECULAR PSYCHIATRY

Control of Intermale Aggression by Medial Prefrontal Cortex Activation in the Mouse

(2014) Aki Takahashi et al.   PLoS One

Medial prefrontal activity during delay period contributes to learning of a working memory task

(2014) Ding Liu et al.   SCIENCE

Enhancing Depression Mechanisms in Midbrain Dopamine Neurons Achieves Homeostatic Resilience

(2014) A. K. Friedman et al.   SCIENCE

Age and isolation influence steroids release and chemical signaling in male mice

(2014) Carla Mucignat-Caretta et al.   STEROIDS

PIP2 regulation of KCNQ channels: biophysical and molecular mechanisms for lipid modulation of voltage-dependent gating

(2014) Mark A. Zaydman et al.   Frontiers in Physiology

Amygdala-Ventral Pallidum Pathway Decreases Dopamine Activity After Chronic Mild Stress in Rats

(2013) Chun-hui Chang et al.   BIOLOGICAL PSYCHIATRY

Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition

(2013) J Wei et al.   MOLECULAR PSYCHIATRY

The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course

(2013) Bruce S. McEwen et al.   NEURON

Sex differences and chronic stress effects on the neural circuitry underlying fear conditioning and extinction

(2013) Mollee R. Farrell et al.   PHYSIOLOGY & BEHAVIOR

Sex differences in the structural connectome of the human brain

(2013) M. Ingalhalikar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adolescent Stress-Induced Epigenetic Control of Dopaminergic Neurons via Glucocorticoids

(2013) M. Niwa et al.   SCIENCE

Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression

(2013) C Márquez et al.   Translational Psychiatry

Neuromodulation of Thought: Flexibilities and Vulnerabilities in Prefrontal Cortical Network Synapses

(2012) Amy F.T. Arnsten et al.   NEURON

Repeated Stress Causes Cognitive Impairment by Suppressing Glutamate Receptor Expression and Function in Prefrontal Cortex

(2012) Eunice Y. Yuen et al.   NEURON

Isolation rearing attenuates social interaction-induced expression of immediate early gene protein products in the medial prefrontal cortex of male and female rats

(2012) Vanessa L. Wall et al.   PHYSIOLOGY & BEHAVIOR

Corticolimbic Function in Impulsive Aggressive Behavior

(2011) Emil F. Coccaro et al.   BIOLOGICAL PSYCHIATRY

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

(2011) Maurizio Popoli et al.   NATURE REVIEWS NEUROSCIENCE

Prefrontal control of fear: more than just extinction

(2010) Francisco Sotres-Bayon et al.   CURRENT OPINION IN NEUROBIOLOGY

Effects of stress throughout the lifespan on the brain, behaviour and cognition

(2009) Sonia J. Lupien et al.   NATURE REVIEWS NEUROSCIENCE

Stress signalling pathways that impair prefrontal cortex structure and function

(2009) Amy F. T. Arnsten   NATURE REVIEWS NEUROSCIENCE

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

Psychosocial stress reversibly disrupts prefrontal processing and attentional control

(2009) C. Liston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early social deprivation induces disturbed social communication and violent aggression in adulthood.

(2008) Máté Tóth et al.   BEHAVIORAL NEUROSCIENCE

Neuroendocrine dysregulation following early social deprivation in children

(2008) Alison B. Wismer Fries et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Multiple Modes of Network Homeostasis in Visual Cortical Layer 2/3

(2008) A. Maffei et al.   JOURNAL OF NEUROSCIENCE

Why do many psychiatric disorders emerge during adolescence?

(2008) Tomáš Paus et al.   NATURE REVIEWS NEUROSCIENCE

Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders

(2008) Kevin C.F. Fone et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS