β-Glucan-stimulated neutrophil secretion of IL-1α is independent of GSDMD and mediated through extracellular vesicles

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

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Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium

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The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

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A System of Cytokines Encapsulated in ExtraCellular Vesicles

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Protein Deiminase 4 and CR3 Regulate Aspergillus fumigatus and β-Glucan-Induced Neutrophil Extracellular Trap Formation, but Hyphal Killing Is Dependent Only on CR3

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Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in Aspergillus fumigatus Infection

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Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion

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Function and regulation of IL-1α in inflammatory diseases and cancer

(2017) Ankit Malik et al.   IMMUNOLOGICAL REVIEWS

Quantification of Exosomes

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Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

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Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy

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Interleukin 1α and the inflammatory process

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Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP

(2016) Mausita Karmakar et al.   Nature Communications

Neutrophil Integrins and Matrix Ligands and NET Release

(2016) Xian M. O’Brien et al.   Frontiers in Immunology

The Epithelial Danger Signal IL-1α Is a Potent Activator of Fibroblasts and Reactivator of Intestinal Inflammation

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Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

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IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge

(2015) Alayna K. Caffrey et al.   PLoS Pathogens

Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death

(2014) Hazel England et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

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Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1

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An Obligate Role for Membrane-Associated Neutral Sphingomyelinase Activity in Orienting Chemotactic Migration of Human Neutrophils

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Cell-Penetrating Peptide Induces Leaky Fusion of Liposomes Containing Late Endosome-Specific Anionic Lipid

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Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis

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