Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics
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Title
Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics
Authors
Keywords
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Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-03-24
DOI
10.1038/s41598-021-86110-8
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Note: Only part of the references are listed.- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges
- (2020) Chih-Cheng Lai et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Repurposing chlorpromazine to treat COVID-19: The reCoVery study
- (2020) M. Plaze et al. ENCEPHALE-REVUE DE PSYCHIATRIE CLINIQUE BIOLOGIQUE ET THERAPEUTIQUE
- Managing the supportive care needs of those affected by COVID-19
- (2020) Sabrina Bajwah et al. EUROPEAN RESPIRATORY JOURNAL
- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
- (2020) Philippe Gautret et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Autophagy and endocytosis – interconnections and interdependencies
- (2020) Åsa B. Birgisdottir et al. JOURNAL OF CELL SCIENCE
- Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis
- (2020) Mandeep R Mehra et al. LANCET
- Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
- (2020) Yeming Wang et al. LANCET
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Remdesivir for the Treatment of Covid-19 — Preliminary Report
- (2020) John H. Beigel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
- (2020) Joshua Geleris et al. NEW ENGLAND JOURNAL OF MEDICINE
- Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system
- (2020) Shuofeng Yuan et al. PHARMACOLOGICAL RESEARCH
- Convalescent plasma for patients with COVID-19
- (2020) Furong Zeng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Remdesivir for severe acute respiratory syndrome coronavirus 2 causing COVID-19: An evaluation of the evidence
- (2020) Yu-chen Cao et al. Travel Medicine and Infectious Disease
- Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
- (2020) Yadi Zhou et al. Cell Discovery
- Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
- (2020) Jia Liu et al. Cell Discovery
- The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
- (2020) Leon Caly et al. ANTIVIRAL RESEARCH
- Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine
- (2020) Srinivasa Reddy Bonam et al. Autophagy
- Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- COVID vaccine excitement builds as Moderna reports third positive result
- (2020) Ewen Callaway NATURE
- Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Human Coronavirus: Host-Pathogen Interaction
- (2019) To Sing Fung et al. Annual Review of Microbiology
- The ER stress sensor IRE1 and MAP kinase ERK modulate autophagy induction in cells infected with coronavirus infectious bronchitis virus
- (2019) To Sing Fung et al. VIROLOGY
- Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
- (2019) Christian Bailly PHYTOMEDICINE
- The NCATS Pharmaceutical Collection: a 10-year update
- (2019) Ruili Huang et al. DRUG DISCOVERY TODAY
- Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation
- (2017) Kristine L. Witt et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Development and Validation of a Computational Model for Androgen Receptor Activity
- (2016) Nicole C. Kleinstreuer et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Coronaviruses — drug discovery and therapeutic options
- (2016) Alimuddin Zumla et al. NATURE REVIEWS DRUG DISCOVERY
- A cell-based quantitative high-throughput image screening identified novel autophagy modulators
- (2016) Yuan Li et al. PHARMACOLOGICAL RESEARCH
- Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
- (2016) Ruili Huang et al. Nature Communications
- Middle East respiratory syndrome
- (2015) Alimuddin Zumla et al. LANCET
- Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
- (2014) Jennifer Kouznetsova et al. Emerging Microbes & Infections
- AP1 is essential for generation of autophagosomes from the trans-Golgi network
- (2012) Y. Guo et al. JOURNAL OF CELL SCIENCE
- Diagnosing the decline in pharmaceutical R&D efficiency
- (2012) Jack W. Scannell et al. NATURE REVIEWS DRUG DISCOVERY
- Involvement of Autophagy in Coronavirus Replication
- (2012) Helena Maier et al. Viruses-Basel
- SARS-CoV Accessory Protein 3b Induces AP-1 Transcriptional Activity through Activation of JNK and ERK Pathways
- (2011) Bhavna Varshney et al. BIOCHEMISTRY
- Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors
- (2011) Ruili Huang et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics
- (2011) R. Huang et al. Science Translational Medicine
- Dynamic Innate Immune Responses of Human Bronchial Epithelial Cells to Severe Acute Respiratory Syndrome-Associated Coronavirus Infection
- (2010) Tomoki Yoshikawa et al. PLoS One
- Identification of compounds that potentiate CREB signaling as possible enhancers of long-term memory
- (2009) M. Xia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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